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Erenumab-aooe Injection

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Why is this medication prescribed?

An injection called erenumab-aooe is used to lessen the frequency of migraines, which are intense, throbbing headaches that can occasionally be accompanied by nausea and sensitivity to light or sound. The drug erenumab-aooe injection belongs to the monoclonal antibody drug class. It functions by preventing the body’s natural material from acting in a way that results in migraine headaches.

How should this medicine be used?

A solution (liquid) to be injected subcutaneously (under the skin) is how erenumab-aooe injection is delivered. Typically, it is given once every month. Inject erenumab-aooe on or about the same day each month. Ask your doctor or chemist to explain any instructions on your prescription label that you are unsure about following. Administer the erenumab-aooe injection as prescribed. Use it only as directed by your doctor, neither more nor less often.

You might be able to administer the medication yourself at home, or you might ask a friend or family member to do it for you. Ask your doctor to demonstrate how to inject the medication to you or the person giving the shots.

Both a prefilled autoinjector and a prefilled syringe are available for the erenumab-aooe injection. Before injecting the medication, let the syringe and autoinjector reheat to room temperature for 30 minutes away from direct sunlight. Never attempt to reheat the drug by putting it in a hot water bath, microwave, or any other device. Only use one syringe or autoinjector per solution, and inject the entire contents of the syringe. Put spent syringes and an autoinjector in a container that won’t puncture. How to get rid of the puncture-resistant container should be discussed with your doctor or chemist.

Inject erenumab-aooe into the stomach or thigh. If you’re going to have someone else administer the injection, they can also administer it into your upper arm. Injecting into skin that is soft, thick, bruised, red, scaly, hard, or that contains scars or stretch marks is not advised.

Before administering erenumab-aooe, always have a look at it. It ought to be transparent and colourless. If the injection of erenumab-aooe is coloured, hazy, or contains flakes or solid particles, do not use it. Never shake it.

Use a new autoinjector or syringe for each injection if your doctor instructs you to administer two distinct injections one right after the other. Make sure the second injection is not administered at the exact same location as the first if you administer it to the same body site (upper arm, thigh, or stomach) for the two distinct injections.

Although it does not treat migraines, erenumab-aooe injection aids in their prevention. Even if you feel well, continue to administer the erenumab-aooe injection. Erenumab-AOE injection should not be stopped without consulting your doctor.

For a copy of the manufacturer’s information for the patient, ask your chemist or doctor.

Other uses for this medicine

Ask your doctor or chemist for more details if you believe this drug should be used for something else.

What special precautions should I follow?

Before using erenumab-aooe injection,

  • Inform your doctor and chemist if you have any allergies to erenumab-aooe, other medicines, or any of the injection’s ingredients, including latex. Request an ingredient list from your chemist. If you or the person injecting your medication has a latex or rubber allergy, let your doctor know before using the prefilled syringe or autoinjector.
  • Inform your doctor and chemist about any additional prescription and over-the-counter medications, vitamins, herbal items, nutritional supplements, and other drugs you are now taking or intend to take. Your doctor might need to adjust your medication doses or keep a close eye out for any negative side effects.
  • If you have high blood pressure now or ever, let your doctor know.
  • Inform your physician if you are nursing a baby, intend to get pregnant, or are already pregnant. Call your doctor right away if you get pregnant while taking erenumab-aooe injection.

What special dietary instructions should I follow?

Keep eating normally unless your doctor instructs you otherwise.

What should I do if I forget a dose?

If you don’t remember to take your medication at the scheduled time, take it as soon as you do. From the day of your last dose forward, resume your dosing regimen.

What side effects can this medication cause?

The injection of erenumab-aooe may have adverse effects. If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Itching, redness, or pain at the injection site
  • Constipation
  • Cramps
  • Muscles cramping

Some adverse effects can be very harmful. Call your doctor right away if you encounter any of these symptoms, or seek emergency care:

  • Difficulty swallowing or breathing, a rash, hives, itching, or swelling of the face, throat, tongue, lips, or eyes.

Other negative effects from erenumab-aooe injection are possible. If you experience any strange issues while taking this drug, call your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting program online at or by phone at 1-800-332-1088 if you have a serious side event.

What should I know about storage and disposal of this medication?

Keep this medication tightly closed in the original container and out of the reach of children. Keep it cool and out of the way (not in the bathroom) and away from light, excessive heat, and moisture. It can be kept at room temperature in the original container after being taken out of the fridge for up to a week. If the erenumab-aooe injection has been stored at room temperature for longer than seven days, dispose of it. Avoid freezing.

As many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Always lock safety caps and promptly stash medication up and away from young children where it is out of their sight and reach to prevent poisoning.

Unused prescriptions must be disposed of carefully to prevent pets, kids, and other people from ingesting them. You should not, however, dispose of this medication in the toilet. Instead, utilizing a medicine take-back program is the easiest approach to get rid of your medication. To find out about take-back programs in your area, speak with your chemist or the garbage/recycling agency in your city. If you do not have access to a take-back program, see the FDA’s Safe Disposal of Medicines website at for additional information.

In case of emergency/overdose

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Additionally, information can be found online at Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

What other information should I know?

Keep all of your doctor’s appointments. While you are receiving erenumab-aooe injectable therapy, your doctor will frequently check your blood pressure.

Do not share your medication with anybody else. Any queries you may have regarding prescription refills should be directed to your chemist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • Aimovig®
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