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Eravacycline Injection

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Why is this medication prescribed?

Eravacycline injection is a type of antibiotic medication prescribed to treat complicated intra-abdominal infections (cIAI) and complicated urinary tract infections (cUTI). It belongs to a class of antibiotics called tetracyclines and works by inhibiting bacterial protein synthesis, ultimately killing the bacteria responsible for the infection.

How should this medicine be used?

Here’s how Eravacycline injection is typically used:

  • Dosage: The dosage of Eravacycline injection varies depending on the severity of the infection, the patient’s age, weight, and other medical conditions. Your healthcare provider will determine the appropriate dosage for you.
  • Administration: Eravacycline is administered intravenously (IV), meaning it is injected directly into a vein. Healthcare professionals typically administer it in a hospital or clinical setting.
  • Frequency: The frequency of administration also depends on the specific circumstances of the infection being treated. Typically, it is administered once every 12 hours.
  • Duration: The duration of treatment with Eravacycline injection varies depending on the type and severity of the infection. Your healthcare provider will determine the appropriate duration of treatment.
  • Follow-up: It is important to complete the full course of treatment as prescribed by your healthcare provider, even if you start to feel better before the treatment is finished. Stopping the medication prematurely may allow the infection to come back or worsen.
  • Storage: Eravacycline injection should be stored according to the instructions provided by the manufacturer. It is typically stored at room temperature away from light and moisture.
  • Precautions: Inform your healthcare provider about any other medications you are taking, including over-the-counter medications, supplements, and herbal remedies, as they may interact with Eravacycline. Also, inform them about any allergies or medical conditions you have.

It’s crucial to follow your healthcare provider’s instructions carefully when using Eravacycline injection to ensure effective treatment and minimize the risk of side effects or complications. If you have any questions or concerns about the medication or its usage, be sure to discuss them with your healthcare provider.

Other uses for this medicine

Off-label uses of Eravacycline injection may include:

  • Treatment of respiratory tract infections
  • Skin and soft tissue infections
  • Bone and joint infections
  • Bloodstream infections (bacteremia)

What special precautions should I follow?

As for special precautions to follow when using Eravacycline injection:

  • Allergic Reactions: Inform your healthcare provider if you have a known allergy to tetracycline antibiotics or any other allergies. Serious allergic reactions to Eravacycline are rare but can occur.
  • Pregnancy and Breastfeeding: Inform your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding. The safety of Eravacycline during pregnancy and breastfeeding has not been established, and your healthcare provider will weigh the potential risks and benefits before prescribing it.
  • Kidney and Liver Function: Inform your healthcare provider if you have any kidney or liver problems. Dose adjustments may be necessary in patients with impaired kidney or liver function.
  • Drug Interactions: Inform your healthcare provider about all the medications, supplements, and herbal products you are taking, as Eravacycline may interact with certain medications. In particular, Eravacycline may interact with drugs that affect the liver enzymes responsible for metabolizing medications.
  • Development of Resistant Bacteria: Prolonged or repeated use of Eravacycline may result in the development of resistant bacteria. It’s important to use Eravacycline only as prescribed and to complete the full course of treatment, even if you start to feel better.
  • Clostridium difficile Infection: Antibiotic use, including Eravacycline, may increase the risk of Clostridium difficile infection, which causes severe diarrhea. Inform your healthcare provider if you experience diarrhea during or after treatment with Eravacycline.

Always follow your healthcare provider’s instructions and recommendations regarding the use of Eravacycline injection, and do not hesitate to ask any questions or voice any concerns you may have about the medication.


What special dietary instructions should I follow?

Dietary Instructions:

    • There are no specific dietary restrictions associated with eravacycline.
    • However, it’s generally a good idea to take eravacycline with a full glass of water to help prevent stomach upset.
    • Avoid consuming dairy products, antacids, or mineral supplements containing calcium, magnesium, aluminum, or iron within 4 hours before or after taking eravacycline, as these may interfere with its absorption.

What should I do if I forget a dose?

  • If you miss a dose of eravacycline, take it as soon as you remember, unless it’s almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule.
  • Do not double the dose to catch up.
  • If you’re unsure about what to do, contact your healthcare provider or pharmacist for advice.

What side effects can this medication cause?

Eravacycline, like any medication, can cause side effects. Common side effects may include:

  • Nausea and vomiting: Some individuals may experience gastrointestinal upset such as nausea and vomiting while taking eravacycline.
  • Diarrhea: Diarrhea is another common side effect associated with eravacycline use.
  • Headache: Headaches can occur as a side effect of eravacycline treatment.
  • Dizziness: Some individuals may experience dizziness or lightheadedness while taking eravacycline.
  • Injection site reactions: Pain, redness, or swelling at the injection site may occur with intravenous administration of eravacycline.
  • Abnormal liver function tests: Eravacycline may cause changes in liver function tests in some patients.
  • Increased risk of fungal infections: Antibiotic use, including eravacycline, may increase the risk of developing fungal infections such as thrush (oral candidiasis) or vaginal yeast infections.
  • Allergic reactions: While rare, some individuals may experience allergic reactions to eravacycline, which can manifest as rash, itching, swelling, or difficulty breathing. Seek immediate medical attention if you experience any signs of an allergic reaction.

It’s essential to discuss any concerns or unusual symptoms with your healthcare provider promptly. They can provide guidance and determine whether any side effects warrant discontinuation of the medication or further medical evaluation.

What should I know about storage and disposal of this medication?

Storage and Disposal:

  • Storage:
    • Store Eravacycline Injection at room temperature away from light and moisture.
    • Keep it out of reach of children and pets.
    • Do not freeze the medication.
    • Follow any specific storage instructions provided by your pharmacist or healthcare provider.
  • Disposal:
    • Dispose of unused or expired Eravacycline Injection properly according to local regulations or guidelines.
    • Do not flush medications down the toilet or pour them down the drain unless instructed to do so.
    • Consult your pharmacist or local waste disposal authority for guidance on how to safely dispose of medications.

In case of emergency/overdose

  • If you suspect an overdose of Eravacycline Injection, seek emergency medical attention or contact your local poison control center immediately.
  • Overdose symptoms may include severe nausea, vomiting, diarrhea, dizziness, or difficulty breathing.
  • Be prepared to provide information about the amount of medication ingested and any symptoms experienced.

What other information should I know?

  • Inform all healthcare providers involved in your care that you are receiving Eravacycline Injection.
  • Attend all scheduled appointments with your healthcare provider for monitoring and evaluation of your response to treatment.
  • Do not share Eravacycline Injection with others, even if they have similar symptoms, as it may not be appropriate for their condition.
  • Follow your healthcare provider’s instructions regarding laboratory tests or other monitoring while taking Eravacycline Injection.
  • Report any new or worsening symptoms to your healthcare provider promptly.

Always follow your healthcare provider’s instructions and recommendations regarding the use, storage, and disposal of Eravacycline Injection, as well as what to do in case of emergency or overdose. If you have any questions or concerns, do not hesitate to consult your pharmacist or healthcare provider for clarification.

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