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Enablex (Generic Darifenacin)

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Why is this medication prescribed?

Enablex (darifenacin) is a medication primarily prescribed to treat symptoms of overactive bladder (OAB), such as frequent urination, urgency, and urinary incontinence. OAB is a condition characterized by an uncontrollable urge to urinate, often resulting in the need to rush to the bathroom.

Enablex works by blocking specific receptors (muscarinic receptors) in the bladder, which helps to relax the bladder muscle, reducing the frequency and urgency of urination.

How should this medicine be used?

The typical starting dose of Enablex is 7.5 mg once daily. However, your doctor may adjust the dosage based on your individual response and tolerance. Enablex should be taken with water, and it can be taken with or without food.

It’s important to follow your doctor’s instructions regarding dosage and usage carefully. Do not exceed the prescribed dose, and do not stop taking Enablex without consulting your doctor, even if you start to feel better. If you miss a dose, take it as soon as you remember, but do not take two doses at the same time to make up for a missed dose.

Enablex is available in extended-release tablets, so it should be swallowed whole and not crushed, chewed, or broken.

As with any medication, it’s essential to discuss any questions or concerns you may have about Enablex with your doctor or pharmacist. They can provide personalized advice based on your medical history and current medications.

Other uses for this medicine

While darifenacin (Enablex) is primarily prescribed for the treatment of overactive bladder (OAB) symptoms, it may sometimes be used off-label for other conditions. However, any such use should be under the supervision and guidance of a healthcare professional. Off-label uses may include conditions involving bladder control issues or conditions where anticholinergic effects may be beneficial, but these should be determined by a healthcare provider.

What special precautions should I follow?

Special precautions should be observed when taking Enablex. Here are some key points to consider:

  • Allergies: Inform your doctor if you have any allergies to darifenacin or any other medications. This medication may contain inactive ingredients that could cause allergic reactions or other problems.
  • Medical history: Provide your complete medical history to your doctor, especially if you have a history of certain medical conditions such as narrow-angle glaucoma, kidney problems, liver disease, gastrointestinal obstruction, or urinary retention.
  • Interactions: Inform your doctor about all medications you are currently taking, including prescription, over-the-counter, herbal supplements, and vitamins, as certain medications may interact with darifenacin.
  • Pregnancy and breastfeeding: It is essential to inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding before taking Enablex. The potential risks and benefits should be discussed with your healthcare provider.
  • Driving and operating machinery: Darifenacin may cause dizziness or blurred vision, which can impair your ability to drive or operate machinery. Avoid these activities until you know how this medication affects you.
  • Alcohol: Limit or avoid alcohol consumption while taking Enablex, as alcohol may worsen certain side effects such as dizziness or drowsiness.
  • Side effects: Be aware of potential side effects of Enablex, including dry mouth, constipation, blurred vision, dizziness, and urinary retention. If you experience any severe or persistent side effects, contact your doctor promptly.
  • Dosage: Take Enablex exactly as prescribed by your doctor. Do not adjust the dosage or stop taking the medication without consulting your doctor first.

By following these precautions and your doctor’s guidance, you can safely take Enablex for the treatment of overactive bladder symptoms.

What special dietary instructions should I follow?

Regarding special dietary instructions, there are no specific dietary restrictions associated with taking Enablex. However, it’s essential to maintain a balanced diet and stay hydrated, as dehydration can exacerbate symptoms of overactive bladder.

What should I do if I forget a dose?

If you forget to take a dose of Enablex, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you have any concerns about missed doses or your medication schedule, consult your doctor or pharmacist for guidance.

What side effects can this medication cause?

Enablex (darifenacin) may cause side effects, although not everyone experiences them. Common side effects of Enablex include:

  • Dry mouth: This is one of the most common side effects of Enablex. Sipping water, chewing sugarless gum, or sucking on ice chips may help relieve dry mouth.
  • Constipation: Ensure you maintain a diet rich in fiber, drink plenty of water, and engage in regular physical activity to help prevent constipation. If constipation persists or becomes severe, consult your doctor.
  • Blurred vision: Darifenacin may cause temporary blurred vision or difficulty focusing. Avoid activities such as driving or operating machinery if you experience this side effect.
  • Dizziness: Darifenacin may cause dizziness, especially when standing up quickly. Take caution when changing positions, and avoid sudden movements.
  • Urinary retention: In some cases, darifenacin can cause difficulty urinating or urinary retention. Contact your doctor if you experience a significant decrease in urine output or difficulty emptying your bladder.
  • Dry eyes: Some individuals may experience dry eyes while taking Enablex. Using artificial tears may help alleviate this symptom.
  • Indigestion or upset stomach: If you experience stomach discomfort or indigestion while taking Enablex, try taking the medication with food. If symptoms persist, consult your doctor.
  • Headache: Headaches are a possible side effect of darifenacin. If headaches are severe or persistent, inform your doctor.
  • Fatigue: Darifenacin may cause fatigue or drowsiness in some individuals. Avoid driving or operating machinery if you experience these symptoms.
  • Difficulty sleeping (insomnia): Some people may experience difficulty falling asleep or staying asleep while taking Enablex. If insomnia becomes problematic, consult your doctor for advice.

It’s essential to inform your doctor if you experience any side effects while taking Enablex, especially if they are severe or persistent. Your doctor may adjust your dosage or recommend alternative treatments to help manage side effects. Additionally, if you have any concerns or questions about potential side effects, don’t hesitate to discuss them with your healthcare provider.

What should I know about storage and disposal of this medication?

Storage and disposal:


  • Store Enablex at room temperature between 68°F to 77°F (20°C to 25°C).
  • Keep Enablex in its original packaging, away from moisture, heat, and light.
  • Avoid storing Enablex in the bathroom or near the kitchen sink, where moisture and humidity levels are high.
  • Keep Enablex out of reach of children and pets, as accidental ingestion can be harmful.


  • Dispose of any unused or expired Enablex tablets properly.
  • Do not flush Enablex down the toilet or pour it down the drain unless instructed to do so by your pharmacist or local waste disposal company.
  • Check with your pharmacist or local waste management authority for proper disposal instructions, including any medication take-back programs in your area.

In case of emergency/overdose

In case of emergency or overdose of Enablex, seek immediate medical attention or contact your local poison control center at 1-800-222-1222. Symptoms of overdose may include extreme drowsiness, confusion, hallucinations, blurred vision, dry mouth, difficulty breathing, seizures, or loss of consciousness.

What other information should I know?

  • Inform all healthcare providers involved in your care that you are taking Enablex, including dentists, surgeons, and emergency medical personnel.
  • Attend all scheduled appointments with your doctor for monitoring and dosage adjustments if necessary.
  • Do not share Enablex with others, even if they have similar symptoms, as it may be harmful to them.
  • Carry a list of all your medications, including Enablex, with you at all times, and inform healthcare providers of your medication regimen in case of emergencies.
  • Keep Enablex out of direct sunlight and away from moisture, heat, and extreme temperatures.
  • Do not crush, chew, or break Enablex extended-release tablets. Swallow them whole with water.
  • If you have any questions or concerns about Enablex or its usage, consult your doctor or pharmacist for guidance.

By following these guidelines, you can ensure the safe and effective use of Enablex and minimize potential risks associated with its storage, disposal, and emergency situations.

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