A severe or perhaps fatal allergic reaction could be brought on by rasburicase injection. Inform your physician or nurse as soon as possible if you encounter any of the following signs or symptoms: Chest tightness or pain, shortness of breath, dizziness, faintness, hives, rash, itching, swelling of the lips, tongue, or throat, or trouble breathing or swallowing are all possible symptoms. In the event that you have a severe allergic response, your doctor will promptly stop your infusion.

A rasburicase injection may result in severe blood issues. If you have glucose-6-phosphate dehydrogenase (G6PD) deficiency, a hereditary blood disorder, let your doctor know. You’ll likely hear from your doctor that you’re ineligible for rasburicase injection. If you are of African or Mediterranean origin, let your doctor know as well. Please call your doctor right away if you have any of the following signs or symptoms: Headache, shortness of breath, dizziness, weakness, disorientation, rapid or pounding heartbeat, seizures, pale or blue-gray skin colour, yellowing of the skin or eyes, chills, extreme exhaustion, and dark urine are some of the other symptoms that might occur.

Inform the lab staff and your doctor that you are receiving a rasburicase injection prior to any laboratory test.

The hazards of obtaining an injection of rasburicase should be discussed with your doctor.

Rasburicase injection is used to treat high levels of uric acid in patients with specific cancer types who are receiving chemotherapy drugs. Uric acid is a naturally occurring chemical that accumulates in the blood as tumours degrade. Rasburicase injection belongs to the group of drugs known as enzymes. It functions by reducing uric acid so that the body can expel it.

A doctor or nurse can administer rasburicase injection intravenously (into a vein) by mixing the powder with fluids. This can be done in a hospital or clinic. It is typically administered over the course of 30 minutes, once day for up to 5 days. This drug is administered as a one-time treatment that will not be continued.

Ask your doctor or chemist for more details if you think this drug may be prescribed for other conditions.

Before receiving rasburicase injection,

• If you have an allergy to rasburicase, any other medications, or any of the chemicals in rasburicase injection, let your doctor and chemist know right away. Request a list of the ingredients from your chemist.
• Inform your doctor and chemist about any additional prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products you are now taking or intend to use. Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects.
• Inform your doctor of any additional medical issues you now have or have ever had, in addition to the one described in the IMPORTANT WARNING section.
• If you’re expecting a baby, intend to get pregnant, or are currently nursing, let your doctor know. Contact your doctor right away if you find out you’re pregnant while taking a rasburicase injection.
• Inform the surgeon or dentist that you are receiving rasburicase injection if you are undergoing surgery, including dental surgery.

Keep eating normally unless your doctor instructs you otherwise.

Rasburicase could have adverse effects. If any of these symptoms are severe or do not go away, let your doctor know right once:

• Nausea
• Vomiting
• Constipation
• Diarrhea
• Abdominal pain
• Oral sores
• Chest pain
• Fever
• Headache
• Anxiety
• Join pain
• Hands, foot, ankles, or lower legs swelling
• An injection site reaction of discomfort, swelling, redness, or tenderness

Some adverse effects can be very harmful. Call your doctor right away if you encounter any of the signs and symptoms detailed in the IMPORTANT WARNING section.

Other negative effects from rasburicase injection are possible. If you have any strange side effects while taking this medicine, call your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online at http://www.fda.gov/Safety/MedWatch or by phone at 1-800-332-1088 if you suffer a serious side event.

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Additionally, information can be found online at https://www.poisonhelp.org/help. Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

Keep all of your appointments with your physician and the lab. To monitor your body’s reaction to the rasburicase injection, your doctor will request a few lab tests.

Any queries you may have regarding rasburicase injection, ask your chemist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.