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Elahere (Generic Mirvetuximab soravtansine-gynx Injection)

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Your eyes could become damaged if you take mirvetuximab soravtansine-gynx. Call your doctor right away if you have any of the following symptoms: Changes in vision, dry eye, light sensitivity, eye discomfort, eye redness, excessive weeping or discharge from the eye, trouble opening the eyelid due to pain, impaired vision, or the sensation that something is in your eye are some more symptoms.

Keep all of your doctor’s appointments. Before and after your treatment with mirvetuximab soravtansine-gynx, your doctor will recommend an eye exam to check on the health of your eyes.

To lower the risk of ocular toxicity, your doctor may prescribe eye drops for you to use both before and throughout treatment with mirvetuximab soravtansine-gynx. Unless your doctor specifically instructs you to use contacts throughout your mirvetuximab treatment, you should avoid doing so. To prevent further harm to the eyes, your doctor may need to discontinue or modify your mirvetuximab soravtansine-gynx treatment if eye problems appear.

Why is this medication prescribed?

Mirvetuximab soravtansine-gynx injection is used to treat certain types of ovarian (female reproductive organs where eggs are formed), fallopian tube (tube that transports eggs released by the ovaries to the uterus), and peritoneal (layer of tissue that lines the abdomen) cancer in people who have completely responded or partially responded to their first or later chemotherapy treatments. Mirvetuximab soravtansine-gynx is in a class of medications called folate receptor alpha-directed antibody and microtubule inhibitor conjugates. It works by killing cancer cells.

How should this medicine be used?

The mirvetuximab soravtansine-gynx injection is administered intravenously (into a vein) by a physician or nurse at a clinic or hospital. Typically, it is given once every three weeks. How many cycles you should have is something your doctor will decide. You will be given medication to reduce nausea, vomiting, and infusion-related problems prior to each infusion of mirvetuximab soravtansine-gynx. Your doctor or nurse will keep an eye on you throughout the infusion, and depending on any adverse effects you may encounter, they may change the infusion rate or dose of the current infusion or any subsequent infusions.

Other uses for this medicine

Ask your doctor or pharmacist for more details if you believe this drug should be used for something else.

What special precautions should I follow?

Before receiving mirvetuximab soravtansine-gynx injection,

  • If you have any allergies, particularly to any of the inactive ingredients in mirvetuximab soravtansine-gynx injection, tell your doctor and pharmacist right away. A list of the ingredients is available by asking your pharmacist or looking in the medication guide.
  • As you take mirvetuximab soravtansine-gynx injection, be sure to let your doctor and pharmacist know about all prescription and over-the-counter drugs, as well as any vitamins, herbal remedies, and nutritional supplements you are taking or intend to use. The dosage of your drugs may need to be adjusted, and your health may need to be closely watched for any negative effects.
  • Inform your doctor if you now have or previously had renal or liver disease, as well as any vision or eye issues.
  • If you are pregnant or plan to become pregnant, let your doctor know. While having the mirvetuximab soravtansine-gynx injection, you shouldn’t get pregnant. Throughout your treatment with mirvetuximab soravtansine-gynx and for at least 7 months after your last dose, you should use reliable birth control to avoid getting pregnant. Discuss effective birth control options with your doctor. Call your doctor right away if you fall pregnant while taking mirvetuximab soravtansine-gynx. The fetus may be harmed by mirvetuximab soravtansine-gynx.
  • If you are currently breastfeeding or intend to do so, let your doctor know. While taking mirvetuximab soravtansine-gynx and for at least a month following your last dose, you shouldn’t breastfeed.

What special dietary instructions should I follow?

Keep eating normally unless your doctor instructs you otherwise.

What should I do if I forget a dose?

Call your doctor as soon as you can if you are going to be late for a mirvetuximab soravtansine-gynx injection visit.

What side effects can this medication cause?

There may be negative effects from the injection of mirvetuximab soravtansine-gynx. If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Feeling worn out
  • Diarrhea
  • Nausea
  • Abdomen ache
  • Constipation
  • Muscular tremors or weakness

Some adverse effects can be very harmful. Call your doctor right away or seek emergency medical attention if you develop any of these signs or any of the ones detailed in the IMPORTANT WARNING section:

  • Cough, shortness of breath, chest pain, or difficulty breathing
  • Tingling, numbness, or weakness in your hands, feet, which may be new or worsening

Other negative effects from the injection of mirvetuximab soravtansine-gynx are possible. If you experience any strange issues while taking this medicine, contact your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting program online at or by phone at 1-800-332-1088 if you have a serious side event.

What other information should I know?

Keep all of your appointments with your physician and the lab. To monitor your body’s reaction to the injection of mirvetuximab soravtansine-gynx, your doctor may request specific lab tests.

Inform the lab staff and your doctor that you are receiving a mirvetuximab soravtansine-gynx injection prior to any laboratory test.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • Elahere®
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