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Effient (Generic Prasugrel)

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Prasugrel has the potential to result in significant or fatal bleeding. Tell your doctor if you have or have ever had a condition that makes you bleed more easily than usual, recent surgery, any type of injury, a stomach ulcer, bleeding in your stomach, intestines, or head, a stroke or mini-stroke, or a condition that could cause bleeding in your intestines like polyps (abnormal growths in the lining of the large intestine) or diverticulitis (inflamed bulges in the lining of the diver. Inform your doctor and chemist if you are regularly taking any nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen (Advil, Motrin), naproxen (Aleve), or anticoagulants (blood thinners) like warfarin (Coumadin, Jantoven), heparin, or other drugs to treat or prevent blood clots. If you have any of the conditions listed below, are currently on any of these medications, weigh less than 132 lb (60 kg), are older than 75, or have any of the conditions listed above, your doctor may not be able to prescribe you prasugrel. Additionally, if immediate cardiac bypass surgery a particular kind of open heart surgery is likely to be required, your doctor is unlikely to recommend prasugrel. You will most likely experience nosebleeds, prolonged bleeding, and easier bruising when using prasugrel. To speak with a medical professional right away, however, if you suffer any of the following signs: bleeding that is severe, persistent, uncontrollable, or not explained; pink or brown urine; red or black, tarry stools; bloody or coffee-ground-looking vomit; spitting up blood or blood clots; or bruises that don’t seem to be healing properly or that get bigger.

Inform your doctor or dentist that you are taking prasugrel before undergoing any type of surgery, including dental surgery, or other medical procedure. Prasugrel should be stopped at least seven days before to your surgery, as per your doctor’s advice.

When you start taking prasugrel and every time you refill your prescription, your doctor or chemist will give you the medication guide provided by the manufacturer. If you have any questions, carefully read the information and ask your doctor or chemist. The Medication Guide is also available on the Food and Drug Administration (FDA) website.

Consult your doctor regarding the dangers of using prasugrel.

Why is this medication prescribed?

In patients who have experienced a heart attack or significant chest pain and have undergone angioplasty (a surgery to open the blood channels supplying the heart with blood), prasugrel is taken in conjunction with aspirin to avoid serious or life-threatening issues with the heart and blood vessels. The drug prasugrel belongs to the group of drugs known as anti-platelet drugs. It functions by stopping platelets, a kind of blood cell, from clumping together and producing clots that could result in a heart attack or stroke.

How should this medicine be used?

Prasugrel is available as an oral tablet. Typically, it is taken once day, with or without food. Prasugrel should be taken every day at around the same time. Ask your doctor or chemist to explain any instructions on your prescription label that you are unsure about following. Prasugrel should be taken as prescribed. Never take it in larger or less amounts or more frequently than directed by your doctor.

Do not split, chew, break, or crush the tablet; instead, swallow it whole.

Only while you are taking prasugrel will it help you avoid significant issues with your heart and blood vessels. Prasugrel should not be stopped without consulting your doctor. You run an increased risk of dying, having a heart attack, or developing a blood clot if you stop taking prasugrel.

Other uses for this medicine

Ask your doctor or chemist for more details if you believe this drug should be used for something else.

What special precautions should I follow?

Before taking prasugrel,

  • If you have an allergy to prasugrel, clopidogrel (Plavix), ticlopidine (Ticlid), any other medications, or any of the chemicals in prasugrel tablets, let your doctor and chemist know right once. Request a list of the ingredients from your chemist.
  • Inform your doctor and chemist about all prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products that you are now taking or intend to use. Mention any opioids, including codeine, fentanyl (Duragesic, Subsys), hydrocodone (Hysingla, Zohydro ER, in Vicodin), morphine (Astramorph, Kadian), or oxycodone (in Percocet, in Roxicet, among other prescriptions), as well as the medications listed in the IMPORTANT WARNING section. Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects.
  • If you have renal illness now or ever have, let your doctor know.
  • Inform your physician if you are nursing a baby, intend to get pregnant, or are already pregnant. Call your doctor if you become pregnant while taking prasugrel.
  • If you are 75 years of age or older, discuss the advantages and disadvantages of taking prasugrel with your doctor.

What special dietary instructions should I follow?

Keep eating normally unless your doctor instructs you otherwise.

What should I do if I forget a dose?

If you miss a dosage, take it as soon as you recall. If the next dose is soon due, skip the missed one and carry on with your regular dosing plan. To make up for a missing dose, do not take a second one.

What side effects can this medication cause?

Prasugrel could have unwanted effects. If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Dizziness
  • Extreme fatigue
  • Suffering from back, arm, or leg pain
  • Cough

Some adverse effects can be very harmful. Call your doctor right away if you have any of these signs or any of those in the IMPORTANT WARNING section:

  • Fever
  • Weakness
  • Paleness
  • Skin patches that are purple
  • The skin or eyes turning yellow
  • Breathing difficulty
  • Irregular, rapid, or slow heartbeat
  • Headache
  • Confusion
  • Seizures
  • Slow or challenging speech
  • Sudden numbness in a leg or arm
  • Abdominal pain
  • Nausea
  • Vomiting
  • Diarrhea
  • Less urinations
  • Rash
  • Eye, face, mouth, tongue, throat, arms, hands, feet, ankles, or lower legs swelling

Prasugrel may result in additional adverse effects. If you experience any strange issues while taking this medicine, contact your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online at or by phone at 1-800-332-1088 if you suffer a serious side event.

What should I know about storage and disposal of this medication?

Keep this medication tightly closed in the original container and out of the reach of children. Keep the grey cylinder that comes with the medication in the container with the medication to keep the pills dry. Keep it at room temperature and out of the bathroom and other places with excessive heat and moisture.

As many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Always lock safety caps and promptly stash medication up and away from young children where it is out of their sight and reach to prevent poisoning.

Unused prescriptions must be disposed of carefully to prevent pets, kids, and other people from ingesting them. You should not, however, dispose of this medication in the toilet. Instead, utilising a medicine take-back programme is the ideal approach to get rid of your medicines. To find out about take-back programmes in your area, speak with your chemist or the garbage/recycling department in your city. If you do not have access to a take-back programme, visit the FDA’s Safe Disposal of Medicines website at for additional information.

In case of emergency/overdose

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Additionally, information can be found online at Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

What other information should I know?

Keep all of your doctor’s appointments.

No one else should take your medication. Any queries you may have regarding prescription refills should be directed to your chemist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • Effient®
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