Triamterene and hydrochlorothiazide are combined to treat edoema (extra fluid retained in bodily tissues) and high blood pressure in patients who have low potassium levels or for whom low potassium levels in the body could be harmful. The drug class known as diuretics (often referred to as “water pills”) includes the combination of triamterene and hydrochlorothiazide. They function by forcing the kidneys to excrete salt and water from the body through the urine.

High blood pressure is a common illness that, if left untreated, can harm the kidneys, brain, heart, blood vessels, and other organs. Heart disease, a heart attack, heart failure, a stroke, renal failure, eyesight loss, and other issues may result from damage to these organs. Making lifestyle modifications will help you control your blood pressure in addition to taking medication. These adjustments include quitting smoking, drinking alcohol in moderation, eating a diet low in fat and salt, keeping a healthy weight, and exercising for at least 30 minutes most days.

Triamterene and hydrochlorothiazide are sold as tablets and capsules for oral use. It is typically taken once day. Take hydrochlorothiazide and triamterene at roughly the same time each day. Ask your doctor or pharmacist to explain any instructions on your prescription label that you are unsure about following. Take hydrochlorothiazide and triamterene precisely as prescribed. Never take it in larger or less amounts or more frequently than directed by your doctor.

Although not curing edoema or high blood pressure, this drug manages these symptoms. Even if you feel better, keep taking triamterene and hydrochlorothiazide. Without consulting your doctor, do not stop taking triamterene with hydrochlorothiazide.

Ask your doctor or pharmacist for more details if you believe this drug should be used for something else.

Before taking triamterene and hydrochlorothiazide,

• If you have any allergies, including to any of the substances in triamterene and hydrochlorothiazide capsules or tablets, sulfonamide-derived pharmaceuticals (often known as “sulfa drugs”), other medications, or any of these, notify your doctor right away. For a list of the ingredients, consult the patient information or speak with your pharmacist.
• If you’re using amiloride (Midamor), spironolactone (Aldactone, in Aldactazide), or any other triamterene-containing drugs, avoid taking both hydrochlorothiazide and triamterene at the same time. If you are taking one of these medications, your doctor will probably advise you not to take triamterene with hydrochlorothiazide.
• Inform your doctor and pharmacist about all prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products that you are now taking or intend to use. Incorporate any of the following: (Abelcet, Ambisome, Amphotec) amphotericin B; benazepril, captopril, enalapril, lisinopril, moexipril, perindopril, quinapril, ramipril, and trandolapril are examples of angiotensin-converting enzyme (ACE) inhibitors. Benazepril is found in Lotrel, Lotrel, Capoten, Capoten, and Vasotec, and is used to treat hypertension, barbiturates like phenobarbital; blood-thinning medications like warfarin (Coumadin, Jantoven); corticosteroids such betamethasone (Celestone), budesonide (Entocort), cortisone (Cortone), and dexamethasone; and sedatives like phenobarbital (Decadron, Dexpak, Dexasone, others), corticotropin (ACTH, H.P., Acthar Gel); digoxin (Lanoxin); fludrocortisone (Floriner); hydrocortisone (Cortef; Hydrocortone); methylprednisolone (Medrol; Meprolone; Prelone; Rayos); and triamcinolone (Aristocort; Azmacort), narcotic painkillers, laxatives, lithium (Lithobid), drugs for diabetes, gout, or high blood pressure, methenamine (Hiprex, Urex), nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen (Advil, Motrin), naproxen (Aleve), and naproxen sodium (Naprosyn); oral steroids including dexamethasone, methylprednisolone (Medrol), and prednisone (Rayos), as well as potassium supplements or drugs that contain potassium. Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects.
• If you have renal disease or high potassium levels in your blood, let your doctor know. Your physician might advise against taking triamterene plus hydrochlorothiazide.
• Inform your doctor if you have or have had had kidney stones, diabetes, gout, thyroid, heart, or liver illness, as well as systemic lupus erythematosus (SLE, a chronic inflammatory disease).
• If you are pregnant or plan to become pregnant, let your doctor know. If you are using triamterene and hydrochlorothiazide, you should not breastfeed. Call your doctor if you become pregnant while taking triamterene and hydrochlorothiazide.
• If you’re undergoing surgery, including dental surgery, let your doctor or dentist know that you’re taking triamterene and hydrochlorothiazide.
• Plan to use protective clothing, sunglasses, and sunscreen as well as to minimise excessive or prolonged sun exposure. Your skin may become more sensitive to sunlight if you use triamterene or hydrochlorothiazide.
• You should be aware that taking triamterene and hydrochlorothiazide together may increase your risk of fainting if you stand up too rapidly from a laying position. When you initially begin using triamterene and hydrochlorothiazide, this is more typical. Get out of bed gradually, resting your feet on the floor for a few minutes before standing up, to avoid this issue. These negative effects may be exacerbated by alcohol.

Follow these guidelines carefully if your doctor advises you to follow a low-sodium or low-salt diet or to consume more potassium-rich foods in your diet (such as bananas, prunes, raisins, and orange juice).

As soon as you recall, take the missed dose. Skip the missed dose and carry on with your regular dosing plan, nevertheless, if it is almost time for the subsequent dose. Never take two doses at once to make up for missing ones.

Hydrochlorothiazide with triamterene may have negative side effects. If any of these symptoms are severe or do not go away, let your doctor know right once:

• Often urinating
• Headache

Some adverse effects may be severe. Call your doctor right away or go to an emergency room if you encounter any of these signs or any of the ones detailed in the SPECIAL PRECAUTIONS section:

• Symptoms of dehydration and electrolyte imbalance include a dry mouth, thirst, nausea, vomiting, weakness, fatigue, drowsiness, restlessness, confusion, muscle weakness, soreness, or cramps, and a rapid heartbeat.
• Rash
• Hives
• Itching
• Breathing or swallowing challenges
• Suffering from upper stomach ache
• Belly-area swelling or soreness
• Uneasy stomach
• Fever
• Significant bruising or bleeding
• Reduced appetite
• Yellowing of the eyes or skin
• Flu-like signs
• Skin sensations such as tingling, burning, prickling, or creeping
• Unable to move one’s arms or legs
• Sluggish or unpredictable heartbeat

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

Keep this medication tightly closed in the original container and out of the reach of children. Keep it away from excessive heat and moisture at room temperature (not in the bathroom).

Unused prescriptions must be disposed of carefully to prevent pets, kids, and other people from ingesting them. You should not, however, dispose of this medication in the toilet. Instead, utilising a medicine take-back programme is the easiest approach to get rid of your medication. To find out about take-back programmes in your area, speak with your pharmacist or the garbage/recycling department in your city. If you do not have access to a take-back programme, see the FDA’s Safe Disposal of Medications website at http://goo.gl/c4Rm4p for additional information.

Although many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Always lock safety caps and promptly stash medication up and away from young children where it is out of their sight and reach to prevent poisoning. http://www.upandaway.org

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Moreover, information can be found online at https://www.poisonhelp.org/help. Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

Overdose signs could include the following:

• More frequent urination
• Uneasy stomach
• Vomiting
• Weakness or fatigue
• Fever

Keep all of your appointments with your physician and the lab. To monitor your body’s reaction to triamterene, your doctor will request specific lab tests.

Inform the lab staff and your doctor that you are taking triamterene and hydrochlorothiazide prior to any laboratory test.

No one else should take your medication. Any queries you may have regarding medication refills should be directed to your pharmacist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.