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Duracillin A-S (Generic Penicillin G Procaine Injection)

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Why is this medication prescribed?

Duracillin A-S is a combination medication typically prescribed to treat various bacterial infections. It contains ampicillin, an antibiotic, and sulbactam, a beta-lactamase inhibitor. This combination helps to enhance the effectiveness of ampicillin by preventing bacteria from developing resistance to it.

Duracillin A-S is often used to treat infections caused by bacteria that are susceptible to its active ingredients, such as respiratory tract infections, urinary tract infections, skin and soft tissue infections, and certain types of meningitis.

How should this medicine be used?

Duracillin A-S, a combination medication containing ampicillin and sulbactam, is typically used to treat bacterial infections. The dosage and administration of Duracillin A-S can vary depending on the type and severity of the infection, as well as individual patient factors. However, here are general guidelines on how it is commonly used:

  • Dosage: The dosage of Duracillin A-S is determined by your healthcare provider based on factors such as the type and severity of the infection, your weight, and your medical history.
  • Route of Administration: Duracillin A-S is usually administered via injection. It can be given intravenously (into a vein) or intramuscularly (into a muscle). In most cases, healthcare professionals administer the injections in a hospital or clinical setting.
  • Frequency of Administration: The frequency of administration depends on the specific instructions from your healthcare provider. Duracillin A-S may be administered multiple times per day, typically every 6 to 8 hours, to maintain effective levels of the medication in the body.
  • Duration of Treatment: The duration of treatment with Duracillin A-S varies depending on the type and severity of the infection. It’s essential to complete the full course of treatment as prescribed by your healthcare provider, even if you start feeling better before the treatment is finished. Stopping the medication prematurely can result in the recurrence of the infection or the development of antibiotic resistance.
  • Follow-up: Your healthcare provider may schedule follow-up appointments to monitor your response to the medication and adjust the treatment plan if necessary.

It’s crucial to follow your healthcare provider’s instructions and the directions on the prescription label carefully when using Duracillin A-S. If you have any questions or concerns about how to use the medication, don’t hesitate to consult your healthcare provider for guidance.

Other uses for this medicine

Some potential off-label uses of Duracillin A-S might include:

  • Empirical Therapy: Sometimes, Duracillin A-S may be used empirically, meaning it is prescribed based on clinical judgment before specific laboratory confirmation of the bacterial strain causing the infection is obtained.
  • Surgical Prophylaxis: In some cases, Duracillin A-S may be administered before surgery to prevent postoperative infections, especially in procedures where there’s a higher risk of bacterial contamination.
  • Mixed Infections: Duracillin A-S might be considered when a bacterial infection involves multiple types of bacteria or when the infectious agent is unknown but is likely to be susceptible to the antibiotics in Duracillin A-S.

What special precautions should I follow?

As for special precautions, here are some important points to consider when using Duracillin A-S:

  • Allergies: Inform your healthcare provider if you have any known allergies to ampicillin, sulbactam, or any other medications. A history of allergic reactions to penicillins or cephalosporins may increase the risk of an allergic reaction to Duracillin A-S.
  • Medical History: Provide your healthcare provider with a comprehensive medical history, including any history of kidney disease, liver disease, or gastrointestinal problems, as these conditions may affect the dosing or use of Duracillin A-S.
  • Pregnancy and Breastfeeding: Inform your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding. Duracillin A-S should be used with caution during pregnancy and breastfeeding, and the potential benefits and risks should be weighed by your healthcare provider.
  • Drug Interactions: Inform your healthcare provider about all the medications, supplements, and herbal products you are taking, as Duracillin A-S may interact with certain medications, including oral contraceptives and anticoagulants.
  • Resistant Bacteria: Prolonged or repeated use of Duracillin A-S may result in the growth of bacteria that are resistant to the medication. It’s important to use Duracillin A-S only as prescribed and to complete the full course of treatment.
  • Monitoring: Your healthcare provider may monitor you for signs of adverse effects or complications during treatment with Duracillin A-S. Be sure to attend all scheduled follow-up appointments.

Always follow your healthcare provider’s instructions and the directions on the prescription label when using Duracillin A-S. If you have any questions or concerns about its use, don’t hesitate to discuss them with your healthcare provider.

What special dietary instructions should I follow?

Regarding dietary instructions, there are no specific dietary restrictions associated with Duracillin A-S. However, it’s essential to maintain a balanced diet and stay hydrated to support your overall health and aid in recovery from the infection.

What should I do if I forget a dose?

If you forget a dose of Duracillin A-S, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you’re unsure about what to do, contact your healthcare provider or pharmacist for guidance.

What side effects can this medication cause?

Duracillin A-S, like any medication, can cause side effects. Some common side effects associated with Duracillin A-S include:

  • Nausea and vomiting: These gastrointestinal symptoms are relatively common with antibiotics and may occur while taking Duracillin A-S.
  • Diarrhea: Antibiotics can disrupt the natural balance of bacteria in the gut, leading to diarrhea in some individuals.
  • Allergic reactions: Allergic reactions to Duracillin A-S, while less common, can range from mild skin rashes to severe reactions such as anaphylaxis. Seek immediate medical attention if you experience symptoms such as hives, itching, swelling, difficulty breathing, or chest tightness.
  • Skin reactions: Some people may experience skin reactions such as rash, itching, or hives while taking Duracillin A-S.
  • Headache: Headaches are among the reported side effects of Duracillin A-S, though they are usually mild.
  • Injection site reactions: Pain, redness, or swelling at the injection site may occur with intramuscular or intravenous administration of Duracillin A-S.
  • Yeast infections: Antibiotic use can disrupt the natural balance of microorganisms in the body, potentially leading to yeast infections, particularly in women.
  • Abnormal blood tests: Duracillin A-S may cause changes in certain blood test results, such as increased liver enzymes or decreased white blood cell count.
  • Kidney problems: In rare cases, Duracillin A-S can cause kidney problems, especially when used in high doses or for an extended period.

It’s essential to report any side effects or unusual symptoms to your healthcare provider promptly. They can assess your condition and determine whether any adjustments to your treatment are necessary. If you experience severe or persistent side effects, seek medical attention immediately.

What should I know about storage and disposal of this medication?

When it comes to storage and disposal of Duracillin A-S, it’s important to follow these guidelines:

  • Storage: Store Duracillin A-S vials or injections at room temperature away from light and moisture. Avoid storing it in the bathroom or near the kitchen sink where it can be exposed to moisture. Keep it out of reach of children and pets.
  • Disposal: Dispose of unused or expired Duracillin A-S vials or injections properly. Do not flush them down the toilet or pour them down the drain unless instructed to do so. Instead, consult your pharmacist or local waste disposal company for proper disposal methods in your area.

In case of emergency/overdose

  • Seek immediate medical attention: If you suspect an overdose or experience severe symptoms such as difficulty breathing, severe allergic reactions, or loss of consciousness, call emergency services or go to the nearest emergency room.
  • Poison control: You can also contact your local poison control center at 1-800-222-1222 for guidance on what to do in case of an overdose.

What other information should I know?

  • Completion of treatment: Finish the entire course of Duracillin A-S as prescribed by your healthcare provider, even if you start feeling better before completing the medication. Stopping the medication prematurely can lead to the recurrence of infection or the development of antibiotic resistance.
  • Follow-up: Attend all follow-up appointments scheduled by your healthcare provider to monitor your response to Duracillin A-S and assess any potential side effects or complications.
  • Avoid alcohol: While taking Duracillin A-S, it’s best to avoid consuming alcohol, as it may increase the risk of certain side effects or interactions with the medication.
  • Inform healthcare providers: Inform all healthcare providers involved in your care, including dentists and pharmacists, that you are taking Duracillin A-S. This is important to prevent potential drug interactions and ensure appropriate medical management.
  • Storage and handling: If you are administering Duracillin A-S injections at home, follow proper storage and handling procedures outlined by your healthcare provider or pharmacist. Use aseptic techniques to minimize the risk of contamination.
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