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Why is this medication prescribed?

Doxercalciferol is used to treat secondary hyperparathyroidism in some individuals with chronic kidney disease and those receiving dialysis. Secondary hyperparathyroidism is a condition in which the body produces excessive amounts of parathyroid hormone (PTH), a natural substance necessary to regulate the amount of calcium in the blood (medical treatment to clean the blood when the kidneys are not working properly). Doxercalciferol is a member of the vitamin D analogues drug class. It functions by assisting the body in utilising more calcium from dietary sources or supplements and by controlling the body’s synthesis of parathyroid hormone.

How should this medicine be used?

Doxercalciferol is available as a capsule to be swallowed. It is often administered during dialysis sessions three times a week for those getting treatment. It is often taken once day by those with chronic renal disease who do not get dialysis treatments. On the proper days, take doxercalciferol at roughly the same time. Ask your doctor or pharmacist to explain any instructions on your prescription label that you are unsure about following. Doxercalciferol should only be taken as prescribed. Never take it in larger or less amounts or more frequently than directed by your doctor.

Based on how your body reacts to doxercalciferol, your doctor may adjust your dose.

Other uses for this medicine

Ask your doctor or pharmacist for more details if you believe this drug should be used for something else.

What special precautions should I follow?

Before taking doxercalciferol,

  • If you have any allergies, including to doxercalciferol, any other medications, or any of the substances in doxercalciferol capsules, notify your doctor right away. Get a list of the components from your pharmacist.
  • Inform your physician and pharmacist of any additional prescription drugs, vitamins, dietary supplements, and herbal products you are now taking or intend to use. Mention any of the following: phenobarbital, other forms of vitamin D, erythromycin (E.E.S., Ery-Tab, PCE, and others), mineral oil (in laxatives), erythromycin (E.E.S., Ery-Tab, and others), cholestyramine (Prevalite), erythromycin (Ketoconazole), calcium supplements. Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects. Several over-the-counter medicines should not be taken with doxercalciferol, as both you and your carer should be aware. Before taking any over-the-counter drugs while taking doxercalciferol, see your doctor.
  • If you are receiving treatment for dialysis and taking magnesium-containing antacids (Maalox, Mylanta), let your doctor know. Most likely, you won’t be allowed to use these antacids while receiving doxercalciferol treatment from your doctor.
  • If you have high blood levels of calcium or vitamin D, let your doctor know. Most likely, your doctor will advise against using doxercalciferol.
  • Inform your doctor if you have or ever had liver disease, excessive blood levels of phosphorus, or both.
  • Inform your doctor if you are expecting, intend to get pregnant, or are nursing a baby. Call your doctor if you become pregnant while taking doxercalciferol.

What special dietary instructions should I follow?

Only if you additionally consume the recommended amount of calcium from your diet will doxercalciferol be effective. Doxercalciferol use may result in negative side effects if you consume too much calcium through meals. Doxercalciferol won’t be able to control your condition if you don’t consume enough calcium-rich foods. Your physician will advise you on the best calcium-rich foods to eat as well as the recommended daily serving sizes. Inform your doctor if you have trouble consuming enough of these items. Your doctor may then suggest or prescribe a calcium supplement in that situation.

A low-phosphate diet may also be advised by your doctor while you are taking doxercalciferol. Pay close attention to these guidelines.

What should I do if I forget a dose?

If you miss a dosage, take it as soon as you recall. If the next dose is soon due, skip the missed one and carry on with your regular dosing plan. To make up for a missing dose, do not take a second one.

What side effects can this medication cause?

Side effects from doxercalciferol are possible. If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Headache
  • Heartburn
  • Dizziness
  • Issues with sleep
  • Joints hurt
  • Gaining weight

Some adverse effects may be severe. Call your doctor right away if you notice any of these signs:

  • Feeling drained, having trouble concentrating, losing your appetite, being sick, being constipated, feeling more thirsty than usual, urinating more frequently, or losing weight
  • Arms, hands, foot, and legs swelling
  • Breathing difficulty

Further adverse effects of doxercalciferol could exist. If you experience any strange issues while taking this medicine, contact your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep this medication tightly closed in the original container and out of the reach of children. Keep it away from excessive heat and moisture at room temperature (not in the bathroom).

Unused prescriptions must be disposed of carefully to prevent pets, kids, and other people from ingesting them. You should not, however, dispose of this medication in the toilet. Instead, utilising a medicine take-back programme is the easiest approach to get rid of your medication. To find out about take-back programmes in your area, speak with your pharmacist or the garbage/recycling department in your city. If you do not have access to a take-back programme, see the FDA’s Safe Disposal of Medications website at for additional information.

Although many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Always lock safety caps and promptly stash medication up and away from young children where it is out of their sight and reach to prevent poisoning.

In case of emergency/overdose

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Moreover, information can be found online at Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

Overdose symptoms could consist of:

  • Being worn out
  • Having trouble thinking clearly
  • Reduced appetite
  • Nausea
  • Vomiting
  • Constipation
  • Heightened thirst
  • More frequent urination
  • Loss of weight

What other information should I know?

Keep all of your appointments with your physician and the lab. A number of laboratory tests will be requested by your doctor both before and throughout your doxercalciferol treatment.

No one else should take your medication. Any queries you may have regarding medication refills should be directed to your pharmacist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • Hectoral®
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