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Donatussin DM (Generic Phenylephrine)

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Why is this medication prescribed?

Donatussin DM is typically prescribed as a combination medication to relieve symptoms associated with the common cold, allergies, or respiratory tract infections. Let’s break down its components:

  • Chlorpheniramine: This is an antihistamine that helps alleviate symptoms like sneezing, itching, watery eyes, and runny nose associated with allergies or the common cold.
  • Dextromethorphan: This is a cough suppressant that helps to quiet a persistent cough.
  • Phenylephrine: This is a decongestant that works by narrowing the blood vessels in the nasal passages, reducing congestion.

How should this medicine be used?

Donatussin DM should be used exactly as prescribed by your healthcare provider or as directed on the medication label. Here are some general guidelines:

  • Dosage: Take Donatussin DM exactly as directed. Do not take more of it or take it more frequently than recommended. Dosage instructions may vary based on your age, medical condition, and other factors.
  • Administration: Donatussin DM is typically taken orally, with or without food. Follow the instructions provided by your healthcare provider or on the medication label.
  • Timing: Take Donatussin DM at evenly spaced intervals throughout the day to maintain a consistent level of the medication in your body. Do not exceed the recommended dosage or frequency of use.
  • Measuring: Use a measuring device (such as a special measuring spoon or cup) to ensure accurate dosage. Do not use a household spoon, as it may not provide the correct measurement.
  • Avoiding Certain Substances: Avoid consuming alcohol or other medications that may cause drowsiness or dizziness while taking Donatussin DM, as it can enhance these effects.
  • Duration of Use: Use Donatussin DM for the shortest duration necessary to relieve your symptoms. Prolonged or excessive use can lead to tolerance, dependence, or other adverse effects.
  • Consultation: If you have any questions or concerns about how to use Donatussin DM, consult your healthcare provider or pharmacist for guidance.
  • Storage: Store Donatussin DM at room temperature away from moisture and heat. Keep it out of reach of children and pets.

Remember, always follow the instructions provided by your healthcare provider or on the medication label. If you experience any unusual or severe side effects while using Donatussin DM, contact your healthcare provider immediately.

Other uses for this medicine

Apart from its primary use as a cough and cold medication, some off-label uses may include:

  • Management of bronchitis
  • Relief of symptoms associated with asthma exacerbations
  • Treatment of symptoms related to chronic obstructive pulmonary disease (COPD)
  • Aid in clearing mucus from the airways in conditions like pneumonia or bronchiectasis

What special precautions should I follow?

As for special precautions to follow when using Donatussin DM:

  • Medical History: Inform your healthcare provider about any medical conditions you have, especially if you have a history of certain health issues such as high blood pressure, heart disease, thyroid problems, glaucoma, urinary retention, or prostate enlargement. These conditions may influence whether Donatussin DM is safe and appropriate for you.
  • Allergies: Inform your healthcare provider of any allergies you have, particularly if you are allergic to any of the ingredients in Donatussin DM or similar medications.
  • Other Medications: Inform your healthcare provider about all other medications, supplements, and herbal products you are taking. Certain medications may interact with Donatussin DM, potentially affecting its effectiveness or increasing the risk of side effects.
  • Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits of using Donatussin DM with your healthcare provider. It’s essential to weigh the potential risks to the fetus or infant against the benefits of symptom relief.
  • Driving and Operating Machinery: Donatussin DM may cause drowsiness, dizziness, or impair your ability to concentrate. Avoid driving, operating heavy machinery, or engaging in activities that require mental alertness until you know how this medication affects you.
  • Alcohol: Avoid consuming alcohol while taking Donatussin DM, as it can increase the risk of side effects such as drowsiness or dizziness.

Always follow your healthcare provider’s instructions and guidelines for using Donatussin DM, and contact them if you have any questions or concerns about its use or potential side effects.

What special dietary instructions should I follow?

Regarding special dietary instructions, there are typically no specific dietary restrictions associated with Donatussin DM. However, it’s essential to stay hydrated while using this medication, especially if you have a fever or are experiencing symptoms like nasal congestion, which can lead to dehydration. Drinking plenty of fluids can help thin mucus and relieve congestion.

What should I do if I forget a dose?

If you forget a dose of Donatussin DM, take it as soon as you remember. However, if it’s almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one. Taking too much Donatussin DM can increase the risk of side effects. If you’re unsure about what to do, consult your healthcare provider or pharmacist for guidance.

What side effects can this medication cause?

Donatussin DM, like any medication, can cause side effects. Common side effects may include:

  • Drowsiness
  • Dizziness
  • Dry mouth
  • Nausea
  • Blurred vision
  • Constipation
  • Stomach upset
  • Headache
  • Nervousness or restlessness (less common)

These side effects are generally mild and may diminish as your body adjusts to the medication. However, if any of these side effects persist or worsen, notify your healthcare provider promptly.

In some cases, Donatussin DM may cause more serious side effects, although these are less common. These may include:

  • Difficulty urinating or painful urination
  • Rapid or irregular heartbeat
  • Severe dizziness or fainting
  • Severe headache
  • Seizures
  • Mood or mental changes (e.g., hallucinations, agitation)
  • Signs of an allergic reaction, including rash, itching, swelling, severe dizziness, or trouble breathing

If you experience any of these severe side effects, seek immediate medical attention.

It’s important to remember that this is not a complete list of all possible side effects. If you notice any other effects not listed above, contact your healthcare provider or pharmacist. Additionally, if you have concerns about potential side effects or reactions to Donatussin DM, discuss them with your healthcare provider before starting the medication.

What should I know about storage and disposal of this medication?

When it comes to storage and disposal of Donatussin DM, here are some important points to keep in mind:


  • Store Donatussin DM at room temperature, away from light and moisture.
  • Keep it out of reach of children and pets.
  • Do not store Donatussin DM in the bathroom, as moisture and humidity can affect its stability.
  • Avoid storing Donatussin DM in extreme temperatures, such as in the freezer or in direct sunlight.


  • Dispose of unused or expired Donatussin DM properly according to local regulations or guidelines.
  • Do not flush medications down the toilet or pour them down the drain unless instructed to do so by the medication label or by your healthcare provider.
  • Check with your pharmacist or local waste disposal facility for information on safe disposal methods, such as through a drug take-back program.

In case of emergency/overdose

  • Contact emergency services (such as 911) or your local poison control center immediately.
  • If possible, provide them with information about the amount of Donatussin DM ingested, when it was taken, and any symptoms experienced.
  • Do not try to induce vomiting unless instructed to do so by medical professionals.
  • If someone collapses or has difficulty breathing, administer CPR if you are trained to do so, and continue to follow instructions from emergency responders until help arrives.

What other information should I know?

  • Keep track of your dosage schedule and avoid taking more than the recommended dose or using it more frequently than directed.
  • Do not share Donatussin DM with others, even if they have similar symptoms. This medication should be used only as prescribed by a healthcare provider.
  • Inform your healthcare provider about any other medications, supplements, or herbal products you are taking, as they may interact with Donatussin DM.
  • Avoid consuming alcohol while taking Donatussin DM, as it can enhance the sedative effects of the medication and increase the risk of side effects.
  • If you experience any unusual or severe side effects while taking Donatussin DM, contact your healthcare provider promptly.

Following these guidelines can help ensure the safe and effective use of Donatussin DM.

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