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DMF (Generic Dimethyl Fumarate)

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Why is this medication prescribed?

DMF, or Dimethyl fumarate, is a medication primarily prescribed for the treatment of multiple sclerosis (MS). It works by reducing inflammation and preventing damage to the nerve cells in the central nervous system.

How should this medicine be used?

The typical dosage and usage instructions for DMF can vary depending on factors such as the severity of the MS and the individual’s response to the medication. However, it’s usually taken orally in the form of capsules or tablets.

Here’s a general guideline for the usage of DMF:

  • Dosage: The initial recommended dose is usually lower, gradually increasing over time. Commonly, it starts with a low dose for the first week, followed by a higher maintenance dose.
  • Frequency: DMF is often taken twice daily, with or without food. It’s essential to follow the prescribed schedule strictly.
  • Administration: Swallow the capsules or tablets whole with a full glass of water. Do not crush, chew, or break them unless advised by your doctor.
  • Consistency: Try to take DMF at the same times each day to maintain a consistent level of medication in your system.
  • Monitoring: Your doctor may periodically monitor your condition and adjust the dosage accordingly.
  • Side Effects: Be aware of potential side effects and report any unusual symptoms to your healthcare provider promptly.
  • Missed Doses: If you miss a dose, take it as soon as you remember. However, if it’s almost time for your next dose, skip the missed one and continue with your regular schedule. Do not double the dose to catch up.
  • Storage: Store DMF at room temperature away from moisture and heat. Follow any specific storage instructions provided by your pharmacist.

Always consult your healthcare provider for precise dosage instructions and any specific guidelines related to your medical condition. Additionally, they can provide detailed information tailored to your individual needs and circumstances.

Other uses for Ergoloid Mesylates

While DMF (Dimethyl fumarate) is primarily prescribed for the treatment of multiple sclerosis (MS), it has been explored for potential use in other conditions as well. However, its use outside of MS treatment is off-label and should only be considered under the guidance of a healthcare professional. Some of the conditions for which DMF has been studied include psoriasis, inflammatory bowel disease, and certain types of cancer. Research is ongoing to explore its efficacy and safety in these areas.

What special precautions should I follow?

As for special precautions when taking DMF, here are some key points to keep in mind:

  • Allergies: Inform your doctor if you have any allergies, particularly to DMF or any of its ingredients. This is crucial to prevent allergic reactions.
  • Pregnancy and breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits of DMF with your doctor. It’s essential to weigh the potential risks to the fetus or nursing infant against the benefits of treatment.
  • Liver function: DMF may affect liver function, so regular monitoring of liver enzymes may be necessary during treatment. Inform your doctor of any pre-existing liver conditions.
  • Immune system: DMF can weaken the immune system, increasing the risk of infections. Report any signs of infection, such as fever, sore throat, or cough, to your healthcare provider promptly.
  • Kidney function: Individuals with pre-existing kidney problems should use DMF with caution and may require dose adjustments. Your doctor may monitor your kidney function regularly.
  • Drug interactions: Inform your doctor about all medications, supplements, and herbal products you are taking, as they may interact with DMF. Certain medications, such as those that affect the immune system, may increase the risk of side effects or reduce the effectiveness of DMF.
  • Skin reactions: DMF may cause skin reactions such as flushing or itching. Report any unusual skin symptoms to your doctor.
  • Gastrointestinal effects: DMF may cause gastrointestinal side effects such as nausea, diarrhea, or abdominal pain. If these symptoms are severe or persistent, consult your healthcare provider.
  • Driving and operating machinery: DMF may cause dizziness or other central nervous system effects in some individuals. Be cautious when driving or operating machinery until you know how DMF affects you.

Always follow your doctor’s instructions carefully and communicate any concerns or unusual symptoms you experience while taking DMF. They can provide guidance tailored to your individual health needs and circumstances.

What special dietary instructions should I follow?

There are no specific dietary restrictions associated with DMF. However, it’s generally recommended to maintain a healthy and balanced diet to support overall well-being. If you experience gastrointestinal side effects such as nausea or diarrhea, you may find it helpful to eat smaller, more frequent meals and avoid spicy or fatty foods that could exacerbate these symptoms.

What should I do if I forget a dose?

If you miss a dose of DMF, take it as soon as you remember, unless it’s almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double up on doses to make up for a missed one. If you’re unsure about what to do, consult your healthcare provider or pharmacist for guidance.

What side effects can this medication cause?

DMF (Dimethyl fumarate) can cause various side effects, although not everyone will experience them. Common side effects include:

  • Flushing: Some individuals may experience flushing or redness of the skin, particularly in the face and upper body. This usually occurs shortly after taking DMF and may improve over time.
  • Gastrointestinal symptoms: Nausea, diarrhea, abdominal pain, and indigestion are common gastrointestinal side effects of DMF. These symptoms may occur during the initial stages of treatment and often improve with continued use.
  • Headache: Headaches are a common side effect of DMF, especially during the first few weeks of treatment. They typically lessen over time but can be bothersome for some individuals.
  • Liver enzyme elevation: DMF may cause an increase in liver enzymes, which can indicate liver inflammation or damage. Regular monitoring of liver function is usually recommended during treatment.
  • Infections: DMF may suppress the immune system, increasing the risk of infections. Watch for signs of infection such as fever, sore throat, or cough, and inform your healthcare provider if you experience any.
  • Allergic reactions: Allergic reactions to DMF are rare but can occur. Seek medical attention immediately if you experience symptoms such as rash, itching, swelling, dizziness, or difficulty breathing.
  • Decreased white blood cell count: DMF may cause a decrease in white blood cell count, which can increase the risk of infections. Your doctor may monitor your blood cell counts regularly during treatment.
  • Other side effects: Less common side effects of DMF may include dizziness, fatigue, joint pain, back pain, and hair thinning or loss.

It’s essential to report any side effects you experience to your healthcare provider, as they can provide guidance on managing symptoms and may adjust your treatment regimen if necessary. Additionally, if you experience severe or persistent side effects, seek medical attention promptly.

What should I know about storage and disposal of this medication?

Storage and disposal of DMF:

  • Storage: Store DMF at room temperature away from moisture and heat. Keep it in its original packaging or container to protect it from light. Avoid storing it in the bathroom or other humid areas. Follow any specific storage instructions provided by your pharmacist.
  • Disposal: Dispose of unused or expired DMF properly according to local regulations or guidelines. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Consult your pharmacist or local waste disposal authority for information on how to safely dispose of medications.

In case of emergency/overdose

  • Seek medical attention: If you suspect an overdose of DMF or experience severe symptoms such as difficulty breathing, loss of consciousness, or seizures, seek immediate medical assistance. Contact your local emergency services or go to the nearest emergency room.
  • Poison control: You can also contact your local poison control center for guidance on what to do in case of overdose. They can provide advice on managing symptoms and may recommend further medical evaluation or treatment.

What other information should I know?

  • Follow-up appointments: Attend all scheduled follow-up appointments with your healthcare provider to monitor your response to DMF and assess for any potential side effects or complications.
  • Regular monitoring: Your doctor may conduct regular blood tests to monitor your liver function, white blood cell count, and other parameters while taking DMF. Follow their recommendations for monitoring closely.
  • Avoid alcohol: It’s generally advisable to limit or avoid alcohol consumption while taking DMF, as alcohol may increase the risk of liver problems and may exacerbate certain side effects.
  • Inform other healthcare providers: Make sure to inform other healthcare providers, including dentists and specialists, that you are taking DMF. They should be aware of all medications you are taking to avoid potential interactions or complications.
  • Patient support: Consider joining a support group for individuals with multiple sclerosis or other conditions for which DMF is prescribed. Connecting with others who are undergoing similar experiences can provide valuable support and information.
  • Education: Stay informed about your condition and treatment by asking questions and seeking reliable information from reputable sources such as your healthcare provider or patient advocacy organizations.
  • Adherence: Take DMF exactly as prescribed by your healthcare provider. Do not alter the dosage or stop taking the medication without consulting them first, even if you start to feel better.

By following these guidelines and staying informed, you can effectively manage your treatment with DMF and minimize potential risks.

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