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Diutensen-R (Generic Methyclothiazide)

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Why is this medication prescribed?

High blood pressure is treated with methylclothiazide. Methyclothiazide is also used to treat edoema, which is defined as excess fluid retained in bodily tissues and brought on by a variety of medical conditions, such as heart, kidney, and liver disease, as well as edoema brought on by the use of specific drugs, such as oestrogen and corticosteroids. Methyclothiazide belongs to the group of drugs known as diuretics, also known as “water pills”. It functions by causing the kidneys to excrete salt and water from the body through the urine.

High blood pressure is a common illness that, if left untreated, can harm the kidneys, brain, heart, blood vessels, and other organs. Heart disease, a heart attack, heart failure, a stroke, renal failure, eyesight loss, and other issues may result from damage to these organs. Making lifestyle modifications will help you control your blood pressure in addition to taking medication. These adjustments include quitting smoking, drinking alcohol in moderation, eating a diet low in fat and salt, keeping a healthy weight, and exercising for at least 30 minutes most days.

How should this medicine be used?

Methyclothiazide is available as a tablet to be swallowed. It is often taken in the morning, once daily. Methyclothiazide should be taken at the same time each day. Ask your doctor or chemist to explain any instructions on your prescription label that you are unsure about following. Methyclothiazide should be taken as prescribed. Never take it in larger or less amounts or more frequently than directed by your doctor.

Methyclothiazide manages edoema and high blood pressure but does not treat them. Even if you feel good, keep taking methyclothiazide. Without consulting your doctor, do not discontinue taking methyclothiazide.

Other uses for this medicine

Methyclothiazide may also be used to avoid kidney stones in patients with high blood calcium levels, treat patients with diabetes insipidus, treat some electrolyte imbalances, and treat patients with diabetes insipidus. Discuss the potential dangers of using this medicine for your illness with your doctor.

Ask your doctor or chemist for more details if you’re interested in using this medication for any other conditions.

What special precautions should I follow?

Before taking methyclothiazide,

  • If you have any allergies, including to methyclothiazide, sulfonamide drugs, other medications, or any of the substances in methyclothiazide tablets, notify your doctor right away. For a list of the ingredients, consult the patient information or speak with your chemist.
  • Inform your doctor and chemist about all prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products that you are now taking or intend to use. Incorporate any of the following: phenobarbital and secobarbital (Seconal), as well as the corticosteroids budesonide and betamethasone (Celestone), are examples of barbiturates (Entocort), methylprednisolone (Medrol, Meprolone, others), prednisolone (Prelone, others), prednisone (Rayos), and triamcinolone (Aristocort, Azmacort); cortisone (Cortone), dexamethasone (Decadron, Dexpak, Dexasone, others), fludrocortisone (Florinef), hydrocortisone (Cortef, Hydrocortone); digoxin (Lanoxin), lithium (Lithobid), pharmaceuticals for high blood pressure, corticotropin (ACTH, H.P., Acthar Gel), insulin, and nonsteroidal anti-inflammatory drugs (NSAIDs) such ibuprofen (Advil, Motrin, and others) and naproxen (Aleve) (Aleve, Naprosyn, others). Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects.
  • In case you have kidney illness, let your doctor know. Your doctor could advise against taking methyclothiazide.
  • Inform your doctor if you have or have had had liver illness, systemic lupus erythematosus (SLE), excessive cholesterol, gout, asthma, diabetes, or gouty arthritis.
  • Inform your doctor if you are expecting, intend to get pregnant, or are nursing a baby. Call your doctor right away if you get pregnant while taking methyclothiazide.
  • Plan to use protective clothing, sunglasses, and sunscreen in addition to avoiding needless or prolonged sun exposure. Your skin may become more sensitive to sunlight if you use methylclothiazide.
  • You should be aware that methylclothiazide can make you feel faint, lightheaded, and dizzy if you stand up suddenly from a reclining position. When you initially start taking methyclothiazide, this is more typical. Get out of bed gradually, resting your feet on the floor for a few minutes before standing up, to avoid this issue. These negative effects may be exacerbated by alcohol.

What special dietary instructions should I follow?

Follow these guidelines carefully if your doctor advises you to eat or drink more potassium-rich foods (such as bananas, prunes, raisins, and orange juice) or to follow a low-salt or low-sodium diet.

What should I do if I forget a dose?

If you miss a dosage, take it as soon as you recall. If your next dose is approaching, skip the missed one and carry on with your regular dosing regimen. To make up for a missing dose, do not take a second one.

What side effects can this medication cause?

If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Excessive urination
  • Abdominal pain
  • Uneasy stomach
  • Constipation
  • Diarrhoea
  • Reduced appetite
  • Headache
  • Fuzzy vision

Certain adverse effects can be very harmful. Call your doctor right away if you experience any of these symptoms, or go to the hospital for emergency care:

  • Symptoms of dehydration and electrolyte imbalance include a dry mouth, thirst, nausea, vomiting, weakness, fatigue, drowsiness, restlessness, confusion, muscle weakness, soreness, or cramps, and a rapid heartbeat
  • Eyes and skin that have become yellow
  • Fever
  • Flaking or blistering skin
  • Breathing or swallowing challenges
  • Rash
  • Itching
  • Hives

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep this medication tightly closed in the original container and out of the reach of children. Keep it away from excessive heat and moisture at room temperature (not in the bathroom).

Unused prescriptions must be disposed of carefully to prevent pets, kids, and other people from ingesting them. You should not, however, dispose of this medication in the toilet. Instead, utilising a medicine take-back programme is the easiest approach to get rid of your medication. To find out about take-back programmes in your area, speak with your chemist or the garbage/recycling agency in your city. If you do not have access to a take-back programme, see the FDA’s Safe Disposal of Medications website at for additional information.

In case of emergency/overdose

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Moreover, information can be found online at Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

What other information should I know?

Keep all of your appointments with your physician and the lab. Blood tests should be performed occasionally, and your blood pressure should be checked often.

Inform your doctor and the lab staff that you are taking methyclothiazide prior to any laboratory test.

No one else should take your medication. Any queries you may have regarding prescription refills should be directed to your chemist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • Aquatensen®
  • Enduron®
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