Why is this medication prescribed?

Diphenhydramine is commonly prescribed to relieve symptoms of allergies, such as hay fever, hives, and itching, as well as symptoms of the common cold, such as sneezing and runny nose. It is also used as a sleep aid due to its sedative effects. Additionally, diphenhydramine is sometimes used to prevent and treat motion sickness and as a treatment for mild cases of Parkinson’s disease.

How should this medicine be used?

Diphenhydramine should be used exactly as directed by your doctor or as instructed on the label. Follow all dosing instructions carefully. Here are some general guidelines:

• Dosage: The dosage of diphenhydramine can vary depending on the reason for its use, age, and other factors. Always take the dose recommended by your doctor or pharmacist.
• Formulation: Diphenhydramine is available in various forms, including tablets, capsules, liquid, and topical creams or gels. Use the formulation that your doctor has prescribed or that is appropriate for your needs.
• Timing: If using diphenhydramine as a sleep aid, take it 30 minutes before bedtime. If using it for allergies or other conditions, take it as directed by your doctor, usually every 4 to 6 hours as needed.
• Avoid Alcohol: Avoid consuming alcohol while taking diphenhydramine, as it can increase drowsiness and other side effects.
• Be Cautious with Machinery: Diphenhydramine can cause drowsiness and impair your ability to operate machinery or drive. Avoid activities that require alertness until you know how diphenhydramine affects you.
• Do Not Exceed Recommended Dosage: Taking more diphenhydramine than prescribed or recommended can lead to serious side effects. Stick to the recommended dosage and do not exceed it unless instructed by your doctor.
• Consult with a Doctor: If you have any questions or concerns about how to use diphenhydramine, consult your doctor or pharmacist for guidance.

Always read the medication label and follow the instructions provided. If you are unsure about any aspect of using diphenhydramine, seek medical advice promptly.

Other uses for this medicine

Diphenhydramine has been explored for other uses, such as an adjunctive treatment for acute migraine headaches and as a potential treatment for Parkinson’s disease-related psychosis. However, these uses are not as established as its primary uses.

What special precautions should I follow?

As for special precautions when using diphenhydramine:

• Avoid Alcohol: Diphenhydramine can intensify the sedative effects of alcohol, leading to increased drowsiness and impairment. It’s best to avoid alcohol while taking diphenhydramine.
• Medical Conditions: Inform your doctor if you have any medical conditions, especially breathing problems (such as asthma or COPD), glaucoma, high blood pressure, heart disease, liver disease, kidney disease, seizures, or an enlarged prostate. These conditions may affect how diphenhydramine works or interact with other medications.
• Pregnancy and Breastfeeding: It’s important to consult with your doctor before taking diphenhydramine if you are pregnant or breastfeeding. While diphenhydramine is generally considered safe during pregnancy, it’s essential to weigh the potential risks and benefits with your healthcare provider.
• Driving and Operating Machinery: Diphenhydramine can cause drowsiness and impair your ability to concentrate, react quickly, or perform tasks that require alertness. Avoid driving or operating machinery until you know how diphenhydramine affects you.
• Interactions: Diphenhydramine may interact with other medications, including prescription drugs, over-the-counter medicines, vitamins, and herbal supplements. Inform your doctor about all medications you are taking to avoid potential interactions.

Always follow your doctor’s instructions and advice when using Diphenhydramine or any other medication, and never hesitate to ask questions or seek clarification if needed.

What special dietary instructions should I follow?

Special dietary instructions for diphenhydramine are generally not necessary. However, it’s always a good idea to maintain a healthy and balanced diet while taking any medication to support overall health and well-being.

What should I do if I forget a dose?

If you forget to take a dose of diphenhydramine, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are unsure about what to do, consult your healthcare provider or pharmacist for advice.

What side effects can this medication cause?

Diphenhydramine, like any medication, can cause side effects. Common side effects may include:

• Drowsiness: Diphenhydramine is known for its sedative effects, which can cause drowsiness and impair alertness.
• Dry Mouth: It can reduce saliva production, leading to a dry mouth sensation.
• Dizziness: Some individuals may experience dizziness or lightheadedness, especially when getting up from a lying or sitting position.
• Blurred Vision: Diphenhydramine may cause temporary blurred vision or difficulty focusing.
• Constipation: It can slow down bowel movements, leading to constipation in some individuals.
• Urinary Retention: Diphenhydramine may cause difficulty or discomfort in urination by relaxing the muscles in the bladder.
• Confusion or Disorientation: Especially in older adults, diphenhydramine can sometimes cause confusion, memory problems, or disorientation.
• Increased Heart Rate: In some cases, diphenhydramine may cause a temporary increase in heart rate or palpitations.
• Nausea or Upset Stomach: Some individuals may experience stomach discomfort, nausea, or vomiting.
• Allergic Reactions: While rare, some people may experience allergic reactions to diphenhydramine, which can manifest as rash, itching, swelling, or difficulty breathing. Seek immediate medical attention if you experience any signs of an allergic reaction.

It’s essential to note that not everyone will experience these side effects, and the severity of side effects can vary from person to person. If you experience any concerning or persistent side effects while taking diphenhydramine, it’s essential to consult your healthcare provider for further guidance. Additionally, if you experience severe side effects or signs of an allergic reaction, seek medical attention promptly.

What should I know about storage and disposal of this medication?

When it comes to the storage and disposal of diphenhydramine:

• Storage: Store diphenhydramine at room temperature away from moisture, heat, and light. Keep it tightly closed in its original container, out of reach of children and pets.
• Disposal: Dispose of diphenhydramine properly according to local regulations or guidelines. Do not flush medications down the toilet or pour them down the drain unless instructed to do so. Instead, consult your pharmacist or local waste disposal company for proper disposal methods.

In case of emergency/overdose

• Seek Medical Help: If you suspect an overdose or experience severe symptoms such as extreme drowsiness, difficulty breathing, hallucinations, seizures, or loss of consciousness, seek immediate medical attention or contact a poison control center right away.
• Call Emergency Services: If someone has overdosed and is experiencing severe symptoms, call emergency services (such as 911 in the United States) immediately. Provide as much information as possible about the person’s condition and the medication they have taken.

What other information should I know?

• Keep a List of Medications: Keep a list of all medications you are taking, including diphenhydramine, and share it with your healthcare provider. This includes prescription medications, over-the-counter drugs, vitamins, and herbal supplements.
• Avoid Driving or Operating Machinery: Diphenhydramine can cause drowsiness and impair your ability to perform tasks that require alertness, such as driving or operating machinery. Use caution until you know how diphenhydramine affects you.
• Regular Follow-ups: Attend regular follow-up appointments with your healthcare provider to monitor your response to diphenhydramine and discuss any concerns or side effects you may be experiencing.
• Avoid Combining with Alcohol: Avoid consuming alcohol while taking diphenhydramine, as it can increase drowsiness and impair your judgment and coordination.
• Inform Healthcare Providers: Inform any healthcare providers or emergency responders that you are taking diphenhydramine if you require medical treatment or procedures. This helps ensure appropriate care and avoids potential drug interactions.