Dinutuximab injection can result in serious or fatal side effects that can happen during treatment or up to 24 hours later. While getting the infusion and for at least 4 hours later, a doctor or nurse will keep a close eye on your child to administer treatment in case of a severe reaction to the medication. To avoid or treat dinutuximab reactions, your kid may get additional drugs both before and after the injection. If your kid exhibits any of the following signs throughout your infusion or up to 24 hours after your infusion, call your doctor right once. Hives, a rash, itching, reddening of the skin, fever, chills, trouble breathing or swallowing, swelling of the face, throat, tongue, or lips, feeling lightheaded or dizzy, or a rapid heartbeat.

An injection of dinutuximab may harm nerves, which could lead to pain or other symptoms. Before, during, and after the dinutuximab infusion, your kid can be given pain medicine. If your child experiences any of the following symptoms both during and after the infusion, contact your child’s doctor or other healthcare professional right away: severe or worsening pain, especially in the stomach, back, chest, muscles, or joints; or numbness, tingling, burning, or weakness in the feet or hands.

Keep all of your child’s doctor’s and lab appointments. To monitor your child’s response to the dinutuximab injection, your doctor might prescribe specific tests.

Children who have responded to other therapies for neuroblastoma (a tumour that starts in nerve cells) are treated with dinutuximab injection in combination with other drugs. Monoclonal antibodies are a class of drugs that includes dinutuximab injection. It eliminates cancer cells to work.

In a hospital or infusion centre, a doctor or nurse will provide intravenous (into a vein) injections of dinutuximab over the course of 10 to 20 hours. Within a therapy cycle for up to 5 cycles, it is typically administered for 4 consecutive days.

When your kid receives treatment, be sure to let the doctor know how they are feeling. If your kid develops side effects from the medicine, the doctor may lower the dose or cease the treatment temporarily or permanently.

Ask your doctor or chemist for more details if you believe this drug should be used for something else.

Before receiving dinutuximab injection,

• If your kid has an allergy to dinutuximab, any other medications, or any of the chemicals in dinutuximab injection, let your doctor and chemist know right once. Get a list of the ingredients from your chemist.
• Inform your doctor and chemist about any additional prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products your kid is now taking or intends to take. Your doctor might need to adjust the dosage of your child’s medicine or keep a close eye out for any negative side effects.
• If you think your kid might get pregnant, let your doctor know. The foetus could suffer from a dinutuximab injection. Your child should use birth control if necessary to avoid getting pregnant while receiving dinutuximab treatment and for up to two months after. Discuss effective birth control methods with your doctor. Call your doctor if your child falls pregnant while receiving dinutuximab injection.

Call your child’s doctor as soon as you can if you are unable to make a dinutuximab visit.

The injection of dinutuximab may have adverse effects. If any of these symptoms are severe or do not go away, let your doctor know right once:

• Vomiting
• Diarrhea
• Nausea
• Reduction in hunger
• Gaining weight

Certain adverse effects can be very harmful. Call your doctor right away or seek emergency medical attention if your kid exhibits any of these signs or any of those in the IMPORTANT WARNING section:

• Fever, chills, and other infection-related symptoms
• Fuzzy vision
• Alterations to vision
• Responsiveness to light
• Slack eyelids
• Seizures
• Muscular pain
• Quick heartbeat
• Fatigue
• Urinary blood
• Uncommon bruising or bleeding
• Vomit that is reddish-colored or resembles coffee grounds
• Faeces that is either dark and viscous or contains bright red blood
• Light skin
• Edoema of the lower legs, ankles, feet, or hands
• Breathing difficulty
• Fainting, feeling queasy, or lightheaded

Further negative effects from the injection of dinutuximab are possible. If you have any strange side effects while taking this medicine, call your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.