Why is this medication prescribed?

Diltiazem is prescribed primarily to treat high blood pressure (hypertension) and certain types of chest pain (angina). It belongs to a class of medications called calcium channel blockers, which work by relaxing blood vessels and increasing the supply of blood and oxygen to the heart. This helps lower blood pressure and reduces the workload on the heart, thereby decreasing the occurrence of chest pain.

How should this medicine be used?

Diltiazem is typically prescribed by a doctor and should be used exactly as directed. Here’s a general guide on how diltiazem should be used:

• Dosage: The dosage of diltiazem prescribed will depend on your medical condition and response to treatment. It’s crucial to take the medication exactly as prescribed by your doctor. Do not adjust the dosage unless instructed to do so by your healthcare provider.
• Administration: Diltiazem is usually taken orally in the form of extended-release capsules or tablets. Swallow the capsules or tablets whole with a full glass of water. Do not crush, chew, or break them, as this can interfere with their extended-release mechanism and may lead to side effects.
• Frequency: Diltiazem is typically taken once or twice daily, depending on the formulation prescribed by your doctor. It’s essential to take it at the same time(s) each day to maintain a consistent level of the medication in your bloodstream.
• Food Interactions: Avoid consuming grapefruit or grapefruit juice while taking diltiazem, as it can increase the levels of the medication in your bloodstream and potentially lead to side effects. It’s best to take diltiazem either with food or on an empty stomach, as directed by your doctor.
• Duration: Continue taking diltiazem for as long as prescribed by your doctor, even if you feel well. Suddenly stopping the medication can lead to worsening of your condition. If you have any concerns about the duration of treatment, discuss them with your healthcare provider.
• Missed Dose: If you miss a dose of diltiazem, take it as soon as you remember. However, if it’s almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.
• Consultation: Always consult your healthcare provider if you have any questions or concerns about how to use diltiazem properly. They can provide personalized guidance based on your medical history and condition.

Remember, this information serves as a general guide, and it’s essential to follow the specific instructions provided by your doctor or pharmacist for the safest and most effective use of diltiazem.

Other uses for Ergoloid Mesylates

Some of the off-label uses of diltiazem include:

• Heart arrhythmias: Diltiazem may be used to help control irregular heart rhythms such as atrial fibrillation or atrial flutter.
• Raynaud’s phenomenon: Diltiazem can sometimes be prescribed to help alleviate symptoms of Raynaud’s phenomenon, a condition characterized by reduced blood flow to the fingers and toes, often triggered by cold temperatures or stress.
• Migraine prevention: In some cases, diltiazem may be used off-label to help prevent migraines, particularly in individuals who also have high blood pressure.

What special precautions should I follow?

Special precautions should be taken when using diltiazem, and it’s important to follow your healthcare provider’s instructions carefully. Here are some general precautions to keep in mind:

• Allergies: Inform your doctor if you are allergic to diltiazem or any other medications. This medication may contain inactive ingredients that can cause allergic reactions or other problems.
• Medical History: Before taking diltiazem, inform your doctor about your medical history, especially if you have certain conditions such as liver disease, heart failure, low blood pressure, or any other heart problems.
• Pregnancy and breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits of using diltiazem with your doctor. It’s essential to weigh the potential benefits against the potential risks to the fetus or infant.
• Drug Interactions: Diltiazem can interact with other medications, including certain antibiotics, antifungals, HIV protease inhibitors, and other heart medications. Inform your doctor about all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements, to avoid potential interactions.
• Grapefruit: Avoid consuming grapefruit or grapefruit juice while taking diltiazem, as it can increase the levels of the medication in your bloodstream and potentially lead to side effects.
• Driving and Machinery: Diltiazem may cause dizziness or drowsiness. Avoid driving, operating machinery, or performing any activities that require mental alertness until you know how this medication affects you.
• Regular Monitoring: Your doctor may recommend regular monitoring of your blood pressure, heart rate, and liver function while taking diltiazem to ensure the medication is working effectively and to detect any potential side effects early.

Always follow your healthcare provider’s recommendations and precautions when taking diltiazem or any other medication to ensure safe and effective treatment.

What special dietary instructions should I follow?

• Grapefruit Avoidance: As mentioned, avoid consuming grapefruit or grapefruit juice while taking diltiazem to prevent interactions and maintain medication efficacy.

What should I do if I forget a dose?

• If you miss a dose of diltiazem, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• Do not double the dose to make up for the missed one, as this can increase the risk of side effects.
• If you have questions or concerns about missed doses, consult your healthcare provider or pharmacist for guidance specific to your situation.

What side effects can this medication cause?

Diltiazem, like any medication, can cause side effects. Not everyone experiences these side effects, and their severity can vary from person to person. Common side effects of diltiazem may include:

• Dizziness: Feeling lightheaded or dizzy is a common side effect of diltiazem, especially when standing up quickly from a sitting or lying position.
• Headache: Some people may experience headaches while taking diltiazem. These headaches can range from mild to severe.
• Flushing: Diltiazem may cause flushing or redness of the skin, particularly in the face and neck.
• Swelling: Swelling of the ankles, feet, or hands (peripheral edema) can occur with diltiazem use. This swelling is usually mild but can be bothersome for some individuals.
• Fatigue: Feeling tired or fatigued is a common side effect of diltiazem, especially when first starting the medication or when the dosage is increased.
• Constipation: Diltiazem can sometimes cause constipation, which may be bothersome for some individuals.
• Nausea or Upset Stomach: Some people may experience nausea, vomiting, or stomach discomfort while taking diltiazem.
• Bradycardia: In some cases, diltiazem can slow down the heart rate (bradycardia), especially in individuals with certain heart conditions.
• Rash or Itching: Allergic reactions to diltiazem can occur, leading to a rash, itching, or hives. These reactions are less common but should be reported to a healthcare provider immediately.
• Liver Problems: Rarely, diltiazem can cause liver problems, which may manifest as yellowing of the skin or eyes (jaundice), dark urine, or persistent nausea.
• Other Side Effects: Less common side effects of diltiazem may include shortness of breath, difficulty breathing, mood changes, and muscle cramps.

If you experience any severe or persistent side effects while taking diltiazem, it’s essential to contact your healthcare provider promptly. They can assess your symptoms and determine whether any adjustments to your treatment are necessary. Additionally, if you have any concerns about side effects or the safety of diltiazem, discuss them with your doctor or pharmacist.

What should I know about storage and disposal of this medication?

Storage and Disposal:

• Storage: Store diltiazem at room temperature away from light and moisture. Keep it out of reach of children and pets. Avoid storing diltiazem in the bathroom, where it may be exposed to moisture and humidity.
• Disposal: Dispose of unused or expired diltiazem properly according to local guidelines or regulations. Do not flush medications down the toilet or pour them down the drain unless instructed to do so. Instead, take them to a medication take-back program or follow specific instructions provided by your pharmacist or healthcare provider.

In case of emergency/overdose

• Seek Medical Assistance: If you suspect an overdose of diltiazem or experience severe symptoms such as fainting, difficulty breathing, or loss of consciousness, seek immediate medical attention by calling emergency services (e.g., 911) or your local poison control center.
• Symptom Management: While waiting for medical help, if someone has overdosed on diltiazem and is conscious, encourage them to sit or lie down in a comfortable position. Do not induce vomiting unless instructed by medical professionals.

What other information should I know?

• Regular Monitoring: Your healthcare provider may recommend regular monitoring of your blood pressure, heart rate, and liver function while taking diltiazem to assess its effectiveness and detect any potential side effects early.
• Follow-up Appointments: Attend all scheduled follow-up appointments with your doctor to monitor your response to diltiazem and make any necessary adjustments to your treatment plan.
• Lifestyle Modifications: In addition to taking diltiazem, your doctor may recommend lifestyle modifications to help manage your condition, such as maintaining a healthy diet, engaging in regular exercise, managing stress, and quitting smoking if applicable.
• Medical Alert: Carry a medical alert card or wear a medical alert bracelet or necklace indicating that you are taking diltiazem, especially if you have a history of heart problems or other medical conditions that may require emergency treatment.
• Keep a List of Medications: Maintain an updated list of all medications, supplements, and herbal products you are taking and share it with your healthcare provider to prevent potential drug interactions.

By understanding and following these guidelines, you can help ensure the safe and effective use of diltiazem and minimize the risk of complications. If you have any questions or concerns about diltiazem or its use, don’t hesitate to consult your healthcare provider or pharmacist for guidance.