Use of diazepam nasal spray in combination with other drugs may increase the risk of serious or life-threatening respiratory issues, drowsiness, or coma. Inform your physician if you are currently taking or intend to take any opiate medications, including codeine (in Triacin-C, Tuzistra XR) or hydrocodone (in Anexsia, Norco, or Zyfrel) for coughing or codeine (in Fiorinal) for pain. Other opiate medications include fentanyl (Actiq, Duragesic, Subsys), hydromorphone (Dilaudid, Exalgo) (Conzip, Ultram, in Ultracet). Your doctor will closely monitor you and may need to adjust the dosage of your drugs. Diazepam nasal spray should not be used with any of these drugs if you experience any of the following symptoms. Call your doctor right once or go to an emergency room very away. Unusual lightheadedness, drowsiness, breathing that is sluggish or difficult, or inability to respond. If you are unable to seek treatment on your own, make sure your carer or family members are aware of any symptoms that may be dangerous so they can contact the doctor or emergency services.

Nasal spray diazepam may lead to addiction. Never exceed the recommended dosage, frequency, or duration. Always follow your doctor’s instructions. Inform your doctor if you use or have ever used illicit drugs, consumed excessive amounts of alcohol, or have ever misused any prescription drugs. Don’t consume alcohol or use illicit substances while receiving treatment. Using illicit substances or alcohol while receiving treatment with diazepam also increases your risk of developing these severe, sometimes fatal adverse effects. Additionally let your doctor know if you suffer from depression or any other mental disease now or in the past.

If you take diazepam nasal spray more frequently than advised, it may lead to physical dependence, a condition in which unpleasant physical symptoms appear if a medicine is abruptly withdrawn or used in reduced doses. Without consulting your doctor, do not reduce the dosage or stop taking this drug. Diazepam nasal spray withdrawal symptoms might exacerbate your health and persist anywhere from a few weeks to more than a year if you suddenly stop using it. Your doctor will likely progressively reduce the dosage of your benzodiazepine nasal spray. If you encounter any of the following symptoms, call your doctor or seek emergency medical attention: Unusual movements, ringing in the ears, anxiety, memory issues, difficulty concentrating, sleep issues, seizures, shaking, muscle twitching, changes in mental health, depression, burning or prickling sensations in the hands, arms, legs, or feet, thoughts of harming or killing yourself or others, excessive excitement, or losing touch with reality are some of the symptoms that can accompany these conditions.

The manufacturer’s patient information sheet (Medication Guide) will be sent to you by your doctor or chemist when you start using diazepam nasal spray and each time you get a prescription refill. If you have any questions, carefully read the information and ask your doctor or chemist. The Medication Guide is also available on the manufacturer’s website or the Food and Drug Administration (FDA) website (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm).

When cluster seizures (episodes of heightened seizure activity) occur in adults and children older than 6 years old who are receiving other medications to treat their epilepsy, diazepam nasal spray is used to halt them (seizures). The drug benzodiazepines, which include diazepam, are used to treat anxiety. The way it functions is by reducing the brain’s excessive overactivity.

Diazepam is available as a nasal spray to inhale. It is used as directed by your doctor when necessary. Ask your doctor or chemist to explain any instructions on your prescription label that you are unsure about following. Apply the benzodiazepine nasal spray as indicated. Use it only as directed by your doctor, neither more nor less often.

The doctor will discuss with you and your caretaker the warning signals of the particular type of seizure activity that should be treated with diazepam nasal spray before prescribing it. Moreover, your carer will learn how to use the nasal spray.

Your doctor might advise you to take a second dose of diazepam nasal spray at least 4 hours after the first dose if your seizure does not improve after the first dose. When inhaling a second dose, adhere to your doctor’s instructions.

To be able to control your seizures when they happen, always have diazepam nasal spray on hand or within reach.

Use of the diazepam nasal spray shouldn’t exceed five times per month or more frequently than once every five days. See your doctor if you or your carer believe you require diazepam nasal spray more frequently than this.

• Before using the nasal spray for the first time, be sure you have read all of the manufacturer’s directions.
• Place the seizure sufferer on their side in a secure location so they cannot fall.
• The recipient of the diazepam nasal spray might be lying on their side or back.
• Take the gadget out of the blister pack.
• Avoid pressing the plunger when holding the sprayer between your fingers and thumb.
• Place your fingers against the person’s nose’s bottom and insert the sprayer’s tip there.
• Your thumb should firmly press the plunger.
• Take off the nose’s tip.
• There is only one dose of medication in the sprayer. After using it, properly dispose of it to keep it away from children and pets.
• Maintain the person’s support. Keep an eye on the subject and note when the diazepam nasal spray was administered.
• It appears that the seizures are unusual or worse than normal.
• If seizures occur frequently or last a long time is something you’re concerned about.
• You are concerned if the seizure sufferer’s skin tone or breathing pattern changes.
• The individual is dealing with uncommon or significant issues.

Ask your doctor or chemist for more details if you believe this drug should be used for something else.

Before using diazepam nasal spray,

• If you have any allergies, including those to other medicines, diazepam (Diastat, Valium), or any of the substances in diazepam nasal spray, let your doctor and pharmacist know right once. Get a list of the ingredients from your chemist.
• Inform your doctor and chemist about any vitamins, nutritional supplements, and prescription and over-the-counter drugs you are now taking or intend to take. Any of the following should be mentioned: Blood thinners include anticoagulants like warfarin (Coumadin, Jantoven), carbamazepine (Carbatrol, Epitol, Tegretol, among others), cimetidine (Tagamet), clotrimazole (Lotrimin), cyclosporine (Gengraf, Neoral, Sandimmune), dexamethasone, imipramine (Tofranil), and ketoconazole (Nizoral); drugs for nausea, anxiety, or mental illness; phenobarbital; paclitaxel; omeprazole; phenytoin (Dilantin, Phenytek); omeprazole (Prilosec, Zegerid, in Yosprala); sedatives, sleeping aids, terfenadine (not available in the US), quinidine (in Nuedexta), rifampin (Rifadin, Rimactane, in Rifamate, in Rifater), and others; tranylcypromine (Parnate), troleandomycin (no longer available in the U.S.; TAO), tranquillizers, theophylline (Elixophyllin, Theo-24, Theochron), valproic acid, and tranquillizers (Depakote). Diazepam nasal spray may interact with a wide variety of other drugs, so be careful to inform your doctor about all the drugs you are taking, even if they do not appear on this list. Your doctor might need to adjust your medication doses or keep a close eye out for any negative side effects.
• If you have narrow angle glaucoma, let your doctor know (a serious eye condition that may cause loss of vision). Most likely, your doctor will advise against using diazepam nasal spray.
• Inform your doctor if you currently have or previously had liver, kidney, or lung disease, such as asthma, chronic obstructive pulmonary disease (COPD), pneumonia, or any other lung conditions.
• Inform your physician if you are nursing a baby, intend to get pregnant, or are already pregnant. Call your doctor if you become pregnant while using diazepam nasal spray.
• You should be aware that this medication might make you sleepy. Prior to understanding how this drug affects you, avoid using machinery or driving a car.
• You should be aware that when using diazepam nasal spray for the treatment of epilepsy, your mental health may alter in unexpected ways and you may become suicidal (thinking about injuring or killing oneself, preparing to do so, or trying to do so). One in 500 adults and children aged 5 and older who were treated with anticonvulsants like diazepam in clinical studies for a variety of conditions developed suicidal thoughts while on the medication. Some of these individuals started exhibiting suicidal thoughts and actions as little as one week after beginning the medicine. If you take an anticonvulsant drug like diazepam, there is a chance that your mental state may change, but there is also a chance that your condition will not be addressed and that your mental state will alter. Whether the hazards of using an anticonvulsant drug outweigh the dangers of not using it will be decided by you and your doctor. Any of the following symptoms should prompt you, your family, or your carer to call your doctor immediately away: mania (frenzied, abnormally excited mood); talking or thinking about wanting to hurt yourself or end your life; withdrawing from friends and family; preoccupation with death and dying; giving away prized possessions; or any other unusual changes in behaviour or mood. panic attacks, agitation or restlessness; new or worsening irritability, anxiety, or depression; acting on dangerous impulses; difficulty falling or staying asleep; aggressive, angry, or violent behaviour. Make sure your family or carer is aware of any symptoms that could be significant so they can contact the doctor on your behalf if you are unable to call for help.

If you plan to consume grapefruits or grapefruit juice while taking this medication, consult your doctor.

Side effects from diazepam nasal spray are possible. If any of these symptoms are severe or do not go away, let your doctor know right away:

• Inflamed or painful nose
• Nasal obstruction
• Nosebleeds
• Unfamiliar flavour in the mouth
• Drowsiness
• Dizziness
• Headache
• Unusually “high” feeling
• Diarrhea
• Inadequate coordination
• Unsteadiness

Certain adverse effects can be very harmful. Call your doctor right away or seek emergency medical attention if you develop any of these signs or any of the ones detailed in the IMPORTANT CAUTION section:

• Rash
• Difficulty breathing
• Rage

Further negative effects of diazepam nasal spray are possible. If you experience any strange issues while taking this drug, call your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

Keep this medication tightly closed in the original container and out of the reach of children. Keep it away from light, excessive heat, and moisture at room temperature (not in the bathroom).

Although many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Always lock safety caps and promptly stash medication up and away from young children where it is out of their sight and reach to prevent poisoning. http://www.upandaway.org

Unused prescriptions must be disposed of carefully to prevent pets, kids, and other people from ingesting them. You should not, however, dispose of this medication in the toilet. Instead, utilising a medicine take-back programme is the easiest approach to get rid of your medication. To find out about take-back programmes in your area, speak with your chemist or the garbage/recycling agency in your city. If you do not have access to a take-back programme, see the FDA’s Safe Disposal of Medications website at http://goo.gl/c4Rm4p for additional information.

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Moreover, information can be found online at https://www.poisonhelp.org/help. Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

Overdose symptoms could include:

• Drowsiness
• Confusion
• Coma
• Sluggish reactions

Keep all of your doctor’s appointments.

You or your carer should call your doctor right away if you experience symptoms that are different from your typical seizure patterns.

Do not share your medication with anybody else. Any queries you may have regarding prescription refills should be directed to your chemist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. You should carry this list with you each time you visit a doctor or if you are admitted to a hospital. You should always have this information with you in case of emergencies.