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Diabeta (Generic Glyburide)

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Why is this medication prescribed?

Diabeta, or glyburide, is prescribed primarily to manage type 2 diabetes. It helps lower blood sugar levels by stimulating the pancreas to release more insulin and by improving the body’s utilization of insulin. This medication is typically used when lifestyle changes such as diet and exercise alone aren’t sufficient to control blood sugar levels effectively. It’s an oral medication that can be part of a comprehensive treatment plan for type 2 diabetes, which may also include other medications, diet modifications, and exercise regimens.

How should this medicine be used?

Diabeta (glyburide) should be used exactly as prescribed by your healthcare provider. Typically, it’s taken once daily with breakfast or the first main meal of the day. The dosage can vary depending on factors such as your individual response to the medication, other medications you may be taking, and your overall health condition.

Here are some general guidelines for using Diabeta:

  • Follow your doctor’s instructions: Take Diabeta exactly as prescribed. Do not take more or less of it or take it more often than prescribed.
  • Take it with food: Diabeta is usually taken with breakfast or the first meal of the day to help reduce the risk of stomach upset.
  • Be consistent: Take Diabeta at the same time each day to help maintain steady blood sugar levels.
  • Monitor blood sugar levels: Regularly monitor your blood sugar levels as directed by your doctor. This helps ensure that your diabetes is being controlled effectively and allows your doctor to adjust your medication if necessary.
  • Be cautious of hypoglycemia: Diabeta can cause low blood sugar levels (hypoglycemia). Be aware of the symptoms of hypoglycemia, such as shakiness, sweating, headache, blurred vision, and confusion. Carry a source of sugar (such as glucose tablets or hard candy) to treat low blood sugar if needed.
  • Continue other diabetes management strategies: Diabeta is often used as part of a comprehensive treatment plan for diabetes, which may include diet, exercise, weight management, and other medications. Continue to follow your doctor’s recommendations for managing your diabetes.
  • Regular check-ups: Attend regular check-ups with your healthcare provider to monitor your diabetes and make any necessary adjustments to your treatment plan.

Always consult with your doctor or healthcare provider if you have any questions or concerns about how to use Diabeta or if you experience any side effects or complications. They can provide personalized guidance based on your specific health needs and circumstances.

Other uses for this medicine

Diabeta (glyburide) is primarily used for the treatment of type 2 diabetes and is not typically prescribed for other conditions. However, there may be some off-label uses of Diabeta that your healthcare provider may consider based on their clinical judgment and your individual circumstances. It’s important to follow your doctor’s guidance regarding the appropriate use of Diabeta.

What special precautions should I follow?

As for special precautions to take when using Diabeta:

  • Hypoglycemia: Diabeta can cause low blood sugar levels (hypoglycemia). Be cautious of symptoms such as shakiness, sweating, headache, blurred vision, and confusion. Always carry a source of sugar (such as glucose tablets or hard candy) to treat low blood sugar if needed. Your doctor may advise you on how to manage and prevent hypoglycemia.
  • Liver and kidney function: Inform your healthcare provider if you have any liver or kidney problems before starting Diabeta. Your doctor may need to adjust your dosage or monitor you more closely.
  • Allergies: Let your doctor know if you have any allergies to sulfa drugs or any other medications before taking Diabeta.
  • Pregnancy and breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits of using Diabeta with your doctor. It’s essential to maintain adequate blood sugar control during pregnancy, but the use of Diabeta during pregnancy may require careful monitoring and adjustments in dosage.
  • Surgery and medical procedures: Inform your healthcare provider that you are taking Diabeta before undergoing any surgery or medical procedures. You may need to adjust your medication regimen temporarily.
  • Alcohol: Limit alcohol consumption while taking Diabeta, as it can increase the risk of hypoglycemia.
  • Drug interactions: Inform your doctor about all medications, supplements, and herbal products you are taking, as they may interact with Diabeta and affect its effectiveness or increase the risk of side effects.
  • Regular monitoring: Attend regular check-ups with your healthcare provider to monitor your diabetes control and any potential side effects or complications associated with Diabeta.

Always follow your doctor’s instructions and ask any questions you may have about the use of Diabeta. It’s essential to take this medication exactly as prescribed and to communicate openly with your healthcare provider about your concerns and experiences.

What special dietary instructions should I follow?

  • Follow a balanced diet recommended by your healthcare provider or a registered dietitian.
  • Aim for a diet rich in fruits, vegetables, whole grains, and lean proteins.
  • Limit your intake of sugary foods and beverages.
  • Monitor your carbohydrate intake and spread it evenly throughout the day.
  • Pay attention to portion sizes and avoid overeating.

What should I do if I forget a dose?

If you forget a dose of Diabeta, take it as soon as you remember, unless it’s almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you’re unsure about what to do, consult your doctor or pharmacist for guidance.

What side effects can this medication cause?

Diabeta (glyburide) may cause side effects, although not everyone experiences them. Common side effects of Diabeta include:

  • Hypoglycemia: Low blood sugar levels are the most common side effect of Diabeta. Symptoms of hypoglycemia include shakiness, sweating, headache, blurred vision, confusion, and, in severe cases, loss of consciousness or seizures.
  • Weight Gain: Some people may experience weight gain while taking Diabeta.
  • Gastrointestinal Issues: Diabeta may cause gastrointestinal disturbances such as nausea, vomiting, diarrhea, or constipation.
  • Skin Reactions: Rarely, Diabeta can cause skin reactions such as itching, rash, or redness.
  • Allergic Reactions: Allergic reactions to Diabeta are rare but can occur. Symptoms may include rash, itching, swelling, dizziness, or difficulty breathing. Seek medical attention immediately if you experience any signs of an allergic reaction.
  • Liver Problems: Diabeta can affect liver function in some people, leading to elevated liver enzymes. Inform your doctor if you experience symptoms of liver problems, such as yellowing of the skin or eyes (jaundice), dark urine, or persistent abdominal pain.
  • Blood Disorders: Rarely, Diabeta can cause blood disorders such as thrombocytopenia (low platelet count) or hemolytic anemia (destruction of red blood cells).
  • Vision Changes: Some people may experience blurred vision or other vision changes while taking Diabeta.
  • Hyponatremia: Diabeta may rarely cause low sodium levels in the blood (hyponatremia), which can lead to symptoms such as confusion, seizures, or coma.
  • Other: Other potential side effects of Diabeta include headache, dizziness, fatigue, weakness, and muscle cramps.

It’s essential to discuss any concerns or potential side effects with your doctor before starting Diabeta. They can provide personalized guidance and monitor your response to the medication to ensure its safety and effectiveness for you. If you experience any severe or persistent side effects while taking Diabeta, contact your doctor promptly.

What should I know about storage and disposal of this medication?

Storage and disposal of Diabeta:


  • Store Diabeta at room temperature, away from moisture, heat, and light.
  • Keep the medication in its original container or packaging to protect it from moisture and degradation.
  • Avoid storing Diabeta in the bathroom or kitchen, where moisture levels may be higher.


  • Dispose of expired or unused Diabeta tablets properly.
  • Do not flush Diabeta down the toilet or pour it down the drain unless instructed to do so by your healthcare provider or local waste disposal regulations.
  • Consult your pharmacist or local waste disposal facility for guidance on the proper disposal of medications.

In case of emergency/overdose

If you suspect an overdose of Diabeta or experience severe hypoglycemia (low blood sugar) symptoms, seek emergency medical attention immediately. Symptoms of an overdose may include:

  • Severe hypoglycemia with symptoms such as confusion, seizures, loss of consciousness, or coma
  • Excessive sweating
  • Extreme weakness or fatigue
  • Blurred vision
  • Rapid heartbeat

What other information should I know?

  • Keep a source of sugar (such as glucose tablets or hard candy) with you at all times to treat low blood sugar if it occurs.
  • Wear a medical identification bracelet or necklace indicating that you have diabetes, in case of emergency situations where you may be unable to communicate.
  • Inform healthcare providers, including emergency responders and dentists, that you are taking Diabeta before undergoing any medical procedures or surgeries.
  • Regularly monitor your blood sugar levels as directed by your doctor and attend follow-up appointments to assess your response to Diabeta and adjust your treatment plan if necessary.
  • Follow your doctor’s instructions regarding diet, exercise, and other lifestyle modifications to manage your diabetes effectively.

It’s crucial to be prepared for emergencies and to take steps to ensure the safe storage and disposal of medications like Diabeta. If you have any questions or concerns about how to store, dispose of, or respond to emergencies related to Diabeta, consult your healthcare provider or pharmacist for guidance.

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