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Desoxymetasone (Generic Desoximetasone Topical)

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Why is this medication prescribed?

Desoximetasone topical is used to treat the redness, swelling, itching, and pain associated with a number of skin disorders, such as psoriasis (a skin condition in which red, scaly patches appear on specific parts of the body) and eczema (a skin disease that causes the skin to be dry and itchy and to sometimes develop red, scaly rashes). Desoximetasone is a member of the corticosteroid drug family. To relieve swelling, redness, and itching, it works by triggering natural chemicals in the skin.

How should this medicine be used?

Desoximetasone is available as a cream, ointment, gel, and spray for topical use. Usually, two daily applications are made. Use it at roughly the same intervals each day. Ask your doctor or pharmacist to explain any instructions on your prescription label that you do not understand, and carefully follow their instructions. Just as it is prescribed, use desoximetasone. Never use more or less of it, or apply it more frequently than advised by your doctor. Unless as advised by your physician, avoid using it on other parts of your body or to treat other skin disorders.

The first four weeks of your treatment should see an improvement in your skin’s state. If your symptoms do not get better during this period, call your doctor.

Apply a tiny amount of ointment, cream, spray, or gel to the affected region of skin to cover it with an even, thin layer, and then gently rub it in. This is how to use desoximetasone. Make care to immediately wash your hands after.

Only the skin should be used to apply this medication. Do not ingest desoximetasone topical and avoid getting it in your eyes or mouth. Unless specifically instructed by your doctor, avoid using in the vaginal and rectal areas, as well as in skin folds and armpits.

Desoximetason spray has a risk of burning. When applying betamethasone foam and for a short period afterward, keep away from open flames, fire, and smoke.

Avoid covering the diaper area of a child with plastic trousers or tight diapers when desoximetasone is being applied to the area.

Only the skin should be used to apply this medication. Do not ingest desoximetasone topical and avoid getting it in your eyes or mouth. Unless specifically instructed by your doctor, avoid using it on the face, in genital and rectal areas, as well as in skin folds and armpits.

Only bandage or wrap the treated area if your doctor instructs you to. Such use could exacerbate negative effects.

For a copy of the manufacturer’s information for the patient, ask your pharmacist or doctor.

Other uses for this medicine

Ask your doctor or pharmacist for more details if you believe this drug should be used for something else.

What special precautions should I follow?

Before using desoximetasone topical,

  • If you have an allergy to desoximetasone, any other drugs, or any of the substances in desoximetasone topical solutions, inform your doctor and pharmacist right away. Get a list of the components from your pharmacist.
  • Inform your doctor and pharmacist about any additional prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products you are now taking or intend to use. Include the following information: further topical medicines and more corticosteroids
  • Inform your doctor if you suffer from an infection, any other skin issues, diabetes, Cushing’s syndrome (an abnormal condition brought on by an excess of the hormone corticosteroids), or liver issues.
  • Inform your physician if you are nursing a baby, intend to get pregnant, or are already pregnant. Call your doctor if you become pregnant while taking desoximetason.
  • You should inform your doctor or dentist that you are using desoximetasone topical if you are having surgery, including dental surgery.

What special dietary instructions should I follow?

Keep eating normally unless your doctor instructs you otherwise.

What should I do if I forget a dose?

As soon as you realise you missed a dose, administer it. If the next dose is soon due, skip the missed one and carry on with your regular dosing plan. To make up for a missing dose, avoid applying a second dose.

What side effects can this medication cause?

Side effects are possible with desoximetasone. If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Skin that is scorching, itchy, irritated, red, or dry
  • Rash or small red pimples around the mouth
  • Excessive hair growth
  • Acne
  • Little skin lumps that are white or red
  • Skin that is glossy or bruised
  • Under-the-skin blotches or streaks that are red or purple
  • Dry, brittle, or thin skin
  • Variations in skin tone

Some adverse effects may be severe. Although the following signs are unusual, if you notice any of them, consult your doctor right away:

  • Extreme rash
  • Redness, swelling, pus-oozing, or other indications of a skin infection where desoximetasone was given to the skin

Desoximetasone use in children increases the risk of adverse reactions, such as reduced growth and delayed weight gain. The dangers of applying this medication to your child’s skin should be discussed with your child’s doctor.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep this medication tightly closed in the original container and out of the reach of children. Keep it away from excessive heat and moisture at room temperature (not in the bathroom).

Unused prescriptions must be disposed of carefully to prevent pets, kids, and other people from ingesting them. You should not, however, dispose of this medication in the toilet. Instead, utilising a medicine take-back programme is the easiest approach to get rid of your medication. To find out about take-back programmes in your area, speak with your pharmacist or the garbage/recycling department in your city. If you do not have access to a take-back programme, see the FDA’s Safe Disposal of Medications website at for additional information.

Although many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Always lock safety caps and promptly stash medication up and away from young children where it is out of their sight and reach to prevent poisoning.

In case of emergency/overdose

Dial 1-800-222-1222 to contact your local poison control centre if someone ingests desoximetasone topical. Dial 911 to reach the nearest emergency services if the sufferer has collapsed or has stopped breathing.

What other information should I know?

Keep all of your appointments with your physician and the lab. To monitor how your body is responding to desoximetasone, your doctor may request specific lab tests.

Do not share your medication with anybody else. Any queries you may have regarding medication refills should be directed to your pharmacist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • Topicort®
  • Topicort LP®
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