PrescriptionGiant is a FREE prescription savings program that can save you up to 75% on your prescriptions with or without insurance!

Desonide Topical

Actual product appearance may differ slightly.

Click the CARD below to print or take a screenshot on your mobile phone or tablet. There is no need to download another app!

If you would like to personalize your card enter your full name in the member name field below the card at this link and click the Update button.

Why is this medication prescribed?

Desonide topical is typically prescribed to treat a variety of skin conditions, primarily those associated with inflammation and itching. It’s commonly used for eczema, dermatitis, psoriasis, and certain allergic reactions affecting the skin. Desonide is a corticosteroid, which means it helps to reduce inflammation, redness, swelling, and itching associated with these conditions.

How should this medicine be used?

Desonide topical should be used exactly as prescribed by your healthcare provider. Typically, you’ll follow these general guidelines:

  • Clean and dry the affected area: Before applying Desonide, make sure the skin is clean and dry. Gently wash the area with mild soap and water, then pat it dry with a clean towel.
  • Apply a thin layer: Take a small amount of Desonide cream, lotion, or ointment and apply a thin layer to the affected area of the skin. Avoid applying excessive amounts; a thin layer is usually sufficient.
  • Gently rub in: Use your fingertips to gently rub the medication into the skin until it’s absorbed. Make sure to cover the entire affected area evenly.
  • Wash hands: After applying Desonide, wash your hands thoroughly to remove any medication that may have come into contact with your skin.
  • Frequency of use: Use Desonide as directed by your doctor. Typically, it’s applied once or twice daily, but your doctor may adjust the frequency based on your condition.
  • Duration of use: Use Desonide for the full prescribed duration, even if your symptoms improve before then. However, do not use it for longer than recommended without consulting your doctor.
  • Avoid certain areas: Avoid applying Desonide to areas of the skin that are broken, infected, or irritated unless directed by your doctor.
  • Follow-up: Follow up with your healthcare provider as scheduled to monitor your progress and discuss any concerns or changes in your condition.

Always follow your doctor’s instructions and the directions on the prescription label carefully. If you have any questions or concerns about how to use Desonide topical, don’t hesitate to consult your healthcare provider.

Other uses for this medicine

Desonide topical is primarily used to treat various skin conditions characterized by inflammation, itching, and redness, such as eczema, dermatitis, psoriasis, and certain allergic reactions affecting the skin. However, it may also have other off-label uses, as determined by your healthcare provider. These might include treating other types of dermatitis or skin disorders not explicitly listed in the medication’s official indications.

What special precautions should I follow?

When using Desonide topical, it’s crucial to take certain special precautions to ensure safe and effective use:

  • Follow doctor’s instructions: Use Desonide exactly as prescribed by your healthcare provider. Do not use more than directed or for longer than recommended.
  • Avoid sensitive areas: Avoid getting Desonide cream, lotion, or ointment in your eyes, mouth, or nose. If accidental contact occurs, rinse the affected area with plenty of water.
  • Limit use on large areas: Use Desonide sparingly on large areas of the skin, especially for extended periods, as it may increase the risk of systemic absorption and potential side effects.
  • Avoid occlusive dressings: Unless directed by your doctor, do not cover the treated area with occlusive dressings, such as bandages or plastic wraps, as this can increase absorption of the medication into the bloodstream.
  • Monitor for side effects: Watch for any signs of skin thinning, discoloration, or other adverse reactions while using Desonide. If you notice any concerning symptoms, such as skin irritation or worsening of your condition, contact your doctor promptly.
  • Consult before use in certain conditions: Inform your healthcare provider if you have any underlying medical conditions, such as diabetes or immune system disorders, before using Desonide. They can provide guidance on whether it’s safe for you to use this medication.
  • Pregnancy and breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits of using Desonide with your doctor. While topical corticosteroids are generally considered safe during pregnancy and breastfeeding when used as directed, it’s essential to consult your healthcare provider for personalized advice.
  • Children and elderly: Use Desonide with caution in children and elderly individuals, as they may be more susceptible to certain side effects. Follow your doctor’s recommendations regarding dosage and duration of treatment.

Always inform your healthcare provider about all medications, supplements, and topical products you are using before starting Desonide topical, to avoid potential interactions or adverse effects. If you have any questions or concerns about using Desonide, don’t hesitate to discuss them with your doctor or pharmacist.

What special dietary instructions should I follow?

  • There are typically no specific dietary restrictions associated with using Desonide topical.
  • However, maintaining a healthy diet and staying hydrated can support overall skin health and may complement the treatment.

What should I do if I forget a dose?

  • If you miss a dose of Desonide, apply it as soon as you remember.
  • However, if it’s almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule.
  • Do not apply extra medication to make up for the missed dose, as it may increase the risk of side effects.

What side effects can this medication cause?

Desonide topical is generally well-tolerated when used as directed, but like any medication, it can cause side effects in some people. Common side effects may include:

  • Skin irritation: This can manifest as redness, itching, burning, or stinging at the site of application.
  • Skin thinning: Prolonged use of topical corticosteroids like Desonide can lead to thinning of the skin, especially in areas with repeated application or on sensitive skin.
  • Skin discoloration: Some individuals may experience changes in skin color at the site of application, such as lightening or darkening of the skin.
  • Acne or folliculitis: Desonide may exacerbate acne or cause folliculitis (inflammation of hair follicles) in some cases.
  • Skin infections: Although uncommon, prolonged use of corticosteroids can increase the risk of developing skin infections.
  • Hypersensitivity reactions: Rarely, individuals may experience allergic reactions to Desonide, which can manifest as rash, hives, swelling, or difficulty breathing.
  • Systemic effects: While topical corticosteroids like Desonide are designed to have minimal systemic absorption, prolonged use on large areas of the body or under occlusion may increase the risk of systemic side effects, such as adrenal suppression or Cushing’s syndrome.

It’s important to note that the likelihood and severity of side effects can vary depending on factors such as the duration of use, the amount applied, the area of application, and individual sensitivity. If you experience any concerning side effects while using Desonide topical, or if your symptoms worsen, it’s essential to contact your healthcare provider for further guidance. They can provide personalized advice and may recommend adjusting your treatment regimen if necessary.

What should I know about storage and disposal of this medication?

When it comes to storage and disposal of Desonide topical:


  • Room temperature: Store Desonide topical at room temperature, away from heat, moisture, and direct light.
  • Keep out of reach of children: Store the medication in a secure location where children and pets cannot access it.
  • Avoid extreme temperatures: Do not freeze Desonide, and do not store it in excessively hot or cold environments.
  • Protect from sunlight: Keep the medication in its original container, tightly closed, and away from sunlight.


  • Follow local regulations: Dispose of expired or unused Desonide topical according to local regulations or guidelines. Do not flush it down the toilet or pour it down the drain unless instructed to do so.
  • Check with pharmacist: If you’re unsure about how to dispose of Desonide, consult your pharmacist for guidance.

In case of emergency/overdose

  • Seek medical attention: In case of accidental ingestion or overdose of Desonide topical, contact your local poison control center or seek emergency medical assistance immediately.
  • Symptom management: If someone has applied too much Desonide or ingested it accidentally, monitor for symptoms such as nausea, vomiting, headache, dizziness, or signs of adrenal suppression. Provide supportive care as needed and follow medical advice.

What other information should I know?

  • Regular follow-up: Attend follow-up appointments with your healthcare provider as scheduled to monitor your progress and discuss any concerns or changes in your condition.
  • Inform healthcare providers: Inform all healthcare providers involved in your care, including doctors, dentists, and pharmacists, that you are using Desonide topical, especially if you are scheduled for surgery or dental procedures.
  • Avoid sharing: Do not share Desonide topical with others, even if they have similar symptoms, as it may not be appropriate for their condition.
  • Use as directed: Use Desonide topical exactly as prescribed by your healthcare provider. Do not use more than recommended or for longer than instructed.

By following these guidelines for storage, disposal, and managing emergencies, you can ensure safe and effective use of Desonide topical. If you have any further questions or concerns, don’t hesitate to consult your healthcare provider or pharmacist for assistance.

Copyright © 2023