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Why is this medication prescribed?

Desloratadine is a medication primarily prescribed to relieve symptoms associated with allergies, such as hay fever (allergic rhinitis) and hives (chronic idiopathic urticaria). It belongs to a class of medications known as antihistamines, which work by blocking the action of histamine, a substance in the body that causes allergy symptoms.

How should this medicine be used?

Desloratadine is typically taken orally in the form of tablets or syrup. The dosage and frequency of administration may vary depending on factors such as age, medical condition, and response to treatment. It’s essential to follow the instructions provided by your healthcare provider or as indicated on the medication label. Here’s a general guideline:

  • Dosage: The typical adult dose for Desloratadine is 5 mg once daily. For children, the dosage may be adjusted based on their age and weight, as determined by their healthcare provider.
  • Administration: Desloratadine tablets should be swallowed whole with a full glass of water. They can be taken with or without food. Avoid chewing or crushing the tablets, as this may affect the medication’s effectiveness or cause unwanted side effects.
  • Timing: It’s recommended to take Desloratadine at the same time each day to maintain a consistent level of the medication in your bloodstream.
  • Duration: Continue taking Desloratadine for as long as prescribed by your healthcare provider, even if your allergy symptoms improve. Stopping the medication prematurely may cause symptoms to return.
  • Consultation: If you have any questions or concerns about how to use Desloratadine, don’t hesitate to consult your healthcare provider or pharmacist for guidance.

Always follow your healthcare provider’s instructions regarding the use of Desloratadine to ensure its safe and effective use in managing your allergy symptoms.

Other uses for this medicine

Desloratadine is primarily used for the treatment of allergic conditions, particularly allergic rhinitis (hay fever) and chronic idiopathic urticaria (hives). However, it may also have off-label uses or be prescribed for conditions not specifically listed on the medication label. Some of these off-label uses might include relief from symptoms related to allergic conjunctivitis or allergic skin reactions.

What special precautions should I follow?

As for special precautions when using Desloratadine, here are some key points to keep in mind:

  • Allergies: Inform your healthcare provider if you have any known allergies or sensitivities to Desloratadine or any of its ingredients. Allergic reactions to medications can be severe and require immediate medical attention.
  • Medical Conditions: Before taking Desloratadine, disclose your complete medical history to your healthcare provider, especially if you have liver or kidney problems. Adjustments to the dosage or additional monitoring may be necessary in these cases.
  • Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, consult your healthcare provider before using Desloratadine. While it’s generally considered safe to use during pregnancy and breastfeeding based on limited data, it’s essential to discuss the potential risks and benefits with your healthcare provider.
  • Children and Elderly: Desloratadine is approved for use in children as young as 6 months old, but the dosage may vary based on age and weight. For elderly individuals, cautious use and monitoring may be necessary due to the potential for age-related changes in kidney or liver function.
  • Driving and Operating Machinery: Desloratadine is generally non-sedating, but some individuals may experience drowsiness or dizziness. Use caution when driving, operating machinery, or engaging in activities that require alertness until you know how the medication affects you.
  • Alcohol and Other Medications: Avoid consuming alcohol while taking Desloratadine, as it may increase the risk of side effects. Additionally, inform your healthcare provider about all other medications, supplements, or herbal products you are taking, as they may interact with Desloratadine and affect its effectiveness or safety.

Always follow your healthcare provider’s recommendations and the instructions provided with the medication to ensure safe and effective use of Desloratadine. If you have any concerns or questions about its use, don’t hesitate to discuss them with your healthcare provider or pharmacist.

What special dietary instructions should I follow?

Regarding dietary instructions, there are no specific dietary restrictions associated with Desloratadine. You can take it with or without food, as directed by your healthcare provider.

What should I do if I forget a dose?

If you forget to take a dose of Desloratadine, take it as soon as you remember. However, if it’s almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you’re unsure about what to do, consult your healthcare provider or pharmacist for guidance.

What side effects can this medication cause?

Desloratadine is generally well-tolerated by most individuals, but like any medication, it can cause side effects in some people. Common side effects of Desloratadine may include:

  • Headache: Mild to moderate headaches are among the most commonly reported side effects.
  • Dry Mouth: Some individuals may experience dryness in the mouth or throat.
  • Fatigue: Although Desloratadine is considered non-sedating for most people, some individuals may experience mild drowsiness or fatigue.
  • Nausea: Some people may experience mild nausea or gastrointestinal discomfort.
  • Sore Throat: A sore throat can occur in some individuals as a side effect of Desloratadine.
  • Muscle Pain: Rarely, Desloratadine may cause muscle pain or myalgia.
  • Dizziness: A feeling of dizziness or lightheadedness may occur in some individuals, particularly when first starting the medication.
  • Nervousness or Restlessness: Some individuals may experience feelings of nervousness or restlessness.
  • Allergic Reactions: While rare, serious allergic reactions to Desloratadine can occur. Seek immediate medical attention if you experience symptoms such as rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, or trouble breathing.

It’s important to note that this is not a comprehensive list of all possible side effects. Some people may experience other side effects not listed here. Additionally, individual responses to medications can vary, so not everyone will experience the same side effects, and some may experience none at all.

If you experience any bothersome or persistent side effects while taking Desloratadine, contact your healthcare provider for advice. They can help determine whether the side effects are significant and whether any adjustments to your treatment plan are necessary. If you experience severe or life-threatening symptoms, seek immediate medical attention.

What should I know about storage and disposal of this medication?

When it comes to the storage and disposal of Desloratadine:


  • Store Desloratadine at room temperature away from moisture and heat.
  • Keep the medication tightly closed in its original container, out of reach of children and pets.
  • Do not store Desloratadine in the bathroom or near the kitchen sink, where it could be exposed to moisture.
  • Avoid exposing the medication to extreme temperatures, such as freezing or high heat.


  • Dispose of expired or unused Desloratadine properly according to local regulations or guidelines.
  • Do not flush medications down the toilet or pour them into a drain unless instructed to do so.
  • Consult your pharmacist or local waste disposal company for guidance on the proper disposal of Desloratadine.

In case of emergency/overdose

  • In case of an overdose, seek emergency medical attention or contact a poison control center immediately.
  • Symptoms of an overdose may include extreme drowsiness, confusion, hallucinations, fast or irregular heartbeat, or seizures.
  • If possible, bring the Desloratadine packaging or container to the healthcare provider or emergency room for identification.

What other information should I know?

  • Inform your healthcare provider about all medications, supplements, or herbal products you are taking, as they may interact with Desloratadine.
  • Follow your healthcare provider’s instructions regarding the use of Desloratadine, including dosage, timing, and duration of treatment.
  • Keep all appointments with your healthcare provider for monitoring and evaluation of your condition.
  • Notify your healthcare provider if your symptoms do not improve or worsen while taking Desloratadine.
  • Do not share Desloratadine with others, even if they have similar symptoms, as it may not be appropriate for their condition.

By following these guidelines for storage, disposal, and what to do in case of emergency, you can help ensure the safe and effective use of Desloratadine. If you have any questions or concerns, don’t hesitate to consult your healthcare provider or pharmacist for guidance.

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