WARNING

Descovy is a medication used to treat HIV-1 infection and to reduce the risk of acquiring HIV-1 through sex in individuals at high risk. While it’s generally effective and well-tolerated, there are some risks associated with taking Descovy:

• Kidney Issues: Descovy can cause kidney problems, including kidney failure. This risk is higher in individuals with pre-existing kidney conditions or those taking other medications that affect the kidneys.
• Bone Density Loss: Some people taking Descovy may experience bone density loss, which could lead to osteoporosis or bone fractures. This risk may be higher in individuals with a history of bone issues or those with certain risk factors.
• Lactic Acidosis: In rare cases, Descovy can lead to a condition called lactic acidosis, which is a buildup of lactic acid in the blood. This can be serious and may even be fatal if not treated promptly.
• Immune Reconstitution Syndrome: When starting Descovy, some individuals may experience immune reconstitution syndrome, where the immune system starts to recover and reacts to previously hidden infections. This can cause inflammation in various parts of the body.
• Drug Interactions: Descovy can interact with other medications, potentially reducing their effectiveness or increasing the risk of side effects. It’s important to inform your healthcare provider about all medications you’re taking before starting Descovy.
• Other Common Side Effects: Like any medication, Descovy can cause common side effects such as nausea, diarrhea, headache, and fatigue. These side effects are usually mild and temporary.

It’s essential to discuss the risks and benefits of Descovy with your healthcare provider, especially if you have any pre-existing medical conditions or are taking other medications. They can help determine if Descovy is the right choice for you and monitor for any potential side effects.

Why is this medication prescribed?

Descovy is prescribed primarily for two purposes:

• Treatment of HIV-1 Infection: Descovy, in combination with other antiretroviral medications, is used to treat HIV-1 infection in adults and pediatric patients weighing at least 35 kg (about 77 pounds). It works by reducing the amount of HIV in the body, thereby helping to control the infection and improve the immune system.
• Prevention of HIV-1 Infection: Descovy is also prescribed as pre-exposure prophylaxis (PrEP) to reduce the risk of sexually acquired HIV-1 infection in adults and adolescents at high risk. When taken consistently and correctly, Descovy can significantly lower the chances of contracting HIV-1 through sexual activity.

How should this medicine be used?

As for how Descovy should be used:

• Dosage: The recommended dosage of Descovy may vary depending on whether it’s being used for HIV treatment or prevention. It’s typically taken once daily with or without food.
• Consistency: For both HIV treatment and PrEP, it’s crucial to take Descovy exactly as prescribed by your healthcare provider. Skipping doses or not following the prescribed regimen can reduce its effectiveness.
• Regular Monitoring: While taking Descovy, your healthcare provider will likely monitor your HIV infection or risk status regularly through blood tests and other evaluations. This helps ensure that the medication is working effectively and that any potential side effects are identified early.
• Combination Therapy: When used for HIV treatment, Descovy is usually prescribed as part of a combination regimen that includes other antiretroviral medications. It’s essential to take all prescribed medications as directed to achieve the best possible outcomes.
• Prevention Measures: When using Descovy for HIV prevention, it’s essential to combine it with other preventive measures, such as practicing safer sex and using condoms consistently. Descovy should not be relied upon as the sole method of HIV prevention.

It’s crucial to discuss any questions or concerns about Descovy with your healthcare provider, including its proper use, potential side effects, and how it fits into your overall HIV treatment or prevention plan.

Other uses for this medicine

Other uses for Descovy are limited to those approved by a healthcare provider. It’s specifically indicated for the treatment of HIV-1 infection and is not approved for other uses.

What special precautions should I follow?

As for special precautions to follow when taking Descovy:

• Medical History: Before starting Descovy, inform your healthcare provider about any medical conditions you have, especially kidney problems, bone issues, or hepatitis B infection. This information will help your provider determine if Descovy is safe and appropriate for you.
• Regular Monitoring: While taking Descovy, your healthcare provider will likely monitor your kidney function, bone density, and overall health regularly through blood tests and other evaluations. This monitoring helps detect any potential side effects early and allows for timely interventions if needed.
• Drug Interactions: Descovy can interact with other medications, including certain antiretrovirals, antivirals, and drugs that affect kidney function. Make sure to inform your healthcare provider about all medications, supplements, and herbal products you are taking before starting Descovy.
• Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits of Descovy with your healthcare provider. Descovy should only be used during pregnancy or breastfeeding if the potential benefits outweigh the potential risks.
• Adherence to Treatment: It’s crucial to take Descovy exactly as prescribed by your healthcare provider and to not skip doses. Skipping doses or not following the prescribed regimen can reduce the effectiveness of the medication and increase the risk of developing drug resistance.

By following these precautions and guidelines, you can maximize the benefits of Descovy while minimizing the risks associated with its use. Always consult your healthcare provider if you have any questions or concerns about taking Descovy or any other medication.

What special dietary instructions should I follow?

Special dietary instructions for Descovy typically involve taking it with or without food, as directed by your healthcare provider. There are no specific dietary restrictions associated with Descovy, but maintaining a healthy and balanced diet is advisable, particularly if you have pre-existing medical conditions such as kidney issues or bone problems.

What should I do if I forget a dose?

• Take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose and continue with your regular schedule.
• Do not double the dose to catch up. Taking extra doses can increase the risk of side effects without providing additional benefits.
• Notify your healthcare provider if you frequently forget doses or if you’re unsure about what to do. They can provide guidance and support to help you maintain adherence to your treatment regimen.

What side effects can this medication cause?

Descovy, like any medication, can cause side effects, although not everyone experiences them. Some common side effects of Descovy include:

• Nausea: Feeling sick to your stomach or having the urge to vomit.
• Diarrhea: Frequent, loose, or watery bowel movements.
• Headache: Pain or discomfort in the head, ranging from mild to severe.
• Fatigue: Feeling tired, lacking energy, or experiencing weakness.
• Dizziness: Feeling unsteady or lightheaded, sometimes leading to fainting.
• Insomnia: Difficulty falling asleep or staying asleep through the night.
• Abdominal pain: Discomfort or cramping in the stomach or abdomen.
• Rash: Skin irritation, redness, or itching.
• Decreased appetite: Reduced desire to eat or loss of interest in food.
• Weight loss: Unintentional loss of body weight over time.

These side effects are typically mild to moderate in severity and often improve as your body adjusts to the medication. However, if any of these side effects persist or worsen, or if you experience any other unusual symptoms, it’s essential to notify your healthcare provider.

In addition to the common side effects mentioned above, Descovy may also cause more serious side effects in some individuals. These can include:

• Kidney problems: Descovy may affect kidney function, leading to decreased kidney function, kidney failure, or other kidney-related issues.
• Bone density loss: Some people taking Descovy may experience bone density loss, which could increase the risk of osteoporosis or bone fractures.
• Lactic acidosis: In rare cases, Descovy may cause a serious condition called lactic acidosis, characterized by the buildup of lactic acid in the blood. Symptoms can include weakness, fatigue, muscle pain, difficulty breathing, and abdominal discomfort.
• Immune reconstitution syndrome: When starting Descovy or other HIV medications, some individuals may experience immune reconstitution syndrome, where the immune system starts to recover and reacts to previously hidden infections. This can cause inflammation in various parts of the body.

It’s crucial to report any concerning or severe side effects to your healthcare provider promptly. They can assess the symptoms and determine the appropriate course of action, which may include adjusting your medication regimen or providing supportive care.

What should I know about storage and disposal of this medication?

For storage and disposal of Descovy:

• Storage: Store Descovy tablets at room temperature away from moisture and heat. Keep the medication in its original container, tightly closed, and out of reach of children.
• Disposal: Dispose of unused or expired Descovy tablets properly according to local regulations or guidelines. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Contact your healthcare provider, pharmacist, or local waste disposal authority for information on how to safely dispose of medications.

In case of emergency/overdose

• Seek medical attention: If you suspect an overdose of Descovy or experience symptoms such as severe dizziness, fainting, difficulty breathing, or unusual weakness, seek immediate medical help by calling emergency services or going to the nearest emergency room.
• Poison control: You can also contact your local poison control center at 1-800-222-1222 (in the United States) for guidance on what to do in case of overdose.

What other information should I know?

• Descovy is not a cure for HIV or AIDS but helps to control the infection and improve quality of life.
• It’s important to take Descovy exactly as prescribed by your healthcare provider and to not skip doses.
• Inform your doctor about any other medications, vitamins, or supplements you are taking as they may interact with Descovy.
• Regular monitoring of your HIV infection, kidney function, and bone density may be necessary while taking Descovy.
• Descovy does not prevent other sexually transmitted infections, so it’s important to practice safe sex and use condoms consistently.
• If you miss a dose of Descovy, take it as soon as you remember. However, if it’s almost time for your next dose, skip the missed dose and take your next dose at the regular time. Do not take a double dose to make up for a missed one.

Always consult your healthcare provider or pharmacist if you have any questions or concerns about storing, disposing, or taking Descovy.