Injections of methylprednisolone are used to treat life-threatening allergic reactions. Methylprednisolone injection is used to treat multiple sclerosis, lupus, gastroenteritis, and some forms of arthritis. Multiple sclerosis affects the nerves, while lupus causes the body to attack many of its own organs. Several disorders that affect the blood, skin, eyes, neurological system, thyroid, kidneys, and lungs are also treated with methylprednisolone injection. It is sometimes combined with other drugs to relieve the side effects of low corticosteroid levels (lack of certain substances that are usually produced by the body and are needed for normal body functioning). Methylprednisolone injection belongs to the corticosteroid drug class. The body’s normal natural production of corticosteroids is replaced in order to treat patients with low corticosteroid levels. It also helps cure other illnesses by lowering inflammation and redness and altering how the immune system functions.

Methylprednisolone injection is available as a powder to be combined with liquid and administered intravenously or intramuscularly (into a vein). Moreover, it is available as an injectable suspension that can be given intravenously, intra-articularly (into a joint), or intralesionally (into a lesion). Your illness and how you react to treatment will determine your individual dose regimen.

Methylprednisolone injection can be delivered to you in a hospital or other healthcare facility, or you can be given the medication to use at home. Your doctor will demonstrate how to inject the drug if you choose to use methylprednisolone injection at home. Make sure you comprehend these instructions, and if you have any issues, consult your healthcare professional. If you experience any issues while using methylprednisolone injection, ask your doctor what to do.

To ensure that you are always utilising the lowest dose of methylprednisolone injection that works for you, your doctor may adjust your dose during treatment. If your body is put under unusual stress, such as through surgery, illness, or infection, your doctor could also need to adjust your dose. During your therapy, let your doctor know if your symptoms grow better or worse, if you get sick or experience any changes in your health.

Moreover, methylprednisolone injection is occasionally used to relieve nausea and vomiting brought on by specific cancer chemotherapy regimens as well as to lower the risk of organ rejection. The dangers of using this drug for your illness should be discussed with your doctor.

Ask your doctor or chemist for more details if you believe this drug should be used for something else.

Before receiving methylprednisolone injection,

• If you have any drug allergies, including those to benzyl alcohol, methylprednisolone, other drugs, or any of the substances in methylprednisolone injection, let your doctor and pharmacist know right once. Get a list of the ingredients from your chemist.
• Inform your doctor and chemist about any additional prescription and over-the-counter medications, vitamins, herbal items, nutritional supplements, and other drugs you are now taking or intend to take. Any of the following should be mentioned: Amphotericin B (Abelcet, Ambisome, Amphotec), aminoglutethimide (Cytadren; no longer sold in the U.S.); warfarin (Coumadin, Jantoven) and other anticoagulants (also known as “blood thinners”), aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen (Advil, Motrin), naproxen (Aleve), and selective COX-2 inhibitors, such as celecoxib (Celebrex), carbamazepine (Equetro, Tegretol, Teril), are some examples; cholinesterase inhibitors such as donepezil (Aricept, in Namzaric), galantamine (Razadyne), neostigmine (Bloxiverz), pyridostigmine (Mestinon, Regonol), and rivastigmine (Exelon); cholestyramine (Prevalite); digoxin (Lanoxin), cyclosporine (Gengraf, Neoral, Sandimmune), diuretics (often known as “water pills”), erythromycin (E.E.S., Ery-Tab, Erythrocin, among others), diabetes drugs such as insulin, digoxin, and others; isoniazid (Laniazid, Rifamate, in Rifater); ketoconazole (Nizoral, Xolegel); phenobarbital; oestrogens, including hormonal contraceptives (birth control tablets, patches, rings, implants, and injections); rifabutin (Mycobutin), phenytoin (Dilantin, Phenytek), and rifampin Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects.
• If you have a fungal infection, tell your doctor (other than on your skin or nails). Most likely, your doctor will advise against using methylprednisolone injection. Tell your physician if you also suffer from idiopathic thrombocytopenic purpura (ITP; an ongoing condition that may cause easy bruising or bleeding due to an abnormally low number of platelets in the blood). If you have ITP, your doctor probably won’t inject you with methylprednisolone.
• Inform your doctor if you have or have ever had: TB (a type of lung infection), cataracts (clouding of the eye’s lens), glaucoma (an eye disease), Cushing’s syndrome (a condition in which the body produces too much cortisol), diabetes, high blood pressure, heart failure, or a recent heart attack; emotional issues, depression or other mental illnesses, osteoporosis (a condition in which the bones become brittle and easily break), seizures, ulcers, liver, renal, heart, intestinal, or thyroid disease, myasthenia gravis (a condition in which the muscles grow weak), and emotional issues. Furthermore let your doctor know if you have a herpes eye infection or any other untreated bacterial, parasite, viral, or viral infection anywhere on your body (a type of infection that causes a sore on the eyelid or eye surface).
• Inform your physician if you are nursing a baby, intend to get pregnant, or are already pregnant. Call your doctor if you get pregnant while receiving an injection of methylprednisolone.
• Inform the surgeon or dentist that you are receiving a methylprednisolone injection if you are undergoing surgery, including dental surgery.
• Avoid getting any shots intended to prevent diseases without first consulting your doctor.
• It’s important to be aware that methylprednisolone injections may impair your capacity to fight infection and may shield you from the signs of infection. Avoid contact with sick persons while taking this drug, and wash your hands frequently. Avoid those who have the measles or chicken pox. If you believe you may have come into contact with someone who had the chicken pox or measles, call your doctor right once.

Your doctor might advise you to consume less salt or eat more potassium or calcium. Also, your doctor might advise or prescribe a calcium or potassium supplement. Pay close attention to these guidelines.

Side effects from methylprednisolone injection are possible. If any of these symptoms are severe or do not go away, let your doctor know right once:

• Headache
• Dizziness
• Slowed-down wound and contusion healing
• Acne
• Dry, brittle, or thin skin
• Under-the-skin blotches or streaks that are red or purple
• Skin lesions where the injection was made
• Increasing body fat or a shift in where your body is moving
• Having trouble falling or staying asleep
• Unsuitable happiness
• Significant mood swings and behavioural changes
• Extreme fatigue
• Depression
• Increased perspiration
• Muscular tremor
• Joints hurt
• Dizziness
• Irregular or nonexistent menstruation
• Higher appetite
• Hiccups

Some adverse effects may be severe. Call your doctor right away or seek emergency medical attention if you have any of these symptoms:

• Infection-related symptoms including a sore throat, a fever, chills, or a cough
• Seizures
• Vision issues
• Eye, face, tongue, throat, arms, hands, feet, ankles, or lower legs swelling
• Breathing or swallowing challenges
• Breathing difficulty
• Unexpected weight gain
• Rash
• Hives
• Itching
• Confusion
• Typical skin blemishes in the throat, nose, or mouth
• Tingling, burning, or numbness in the hands, feet, arms, legs, or face

Injections of methylprednisolone may retard a child’s growth. While using methylprednisolone injection, your child’s doctor will closely monitor your child’s growth. The hazards of giving your child this medication should be discussed with your child’s doctor.

Long-term methylprednisolone injection users run the risk of developing cataracts or glaucoma. During your therapy, ask your doctor how frequently you should have your eyes checked and any potential hazards associated with taking methylprednisolone injection.

The chance of developing osteoporosis may increase if you have a methylprednisolone injection. Discuss the dangers of using this drug with your doctor.

Further negative effects from methylprednisolone injection are possible. If you experience any strange issues while taking this drug, call your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Moreover, information can be found online at https://www.poisonhelp.org/help. Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

Keep all of your appointments with your physician and the lab. To monitor how your body is responding to the methylprednisolone injection, your doctor will request a few lab tests.

Inform the lab staff and your doctor that you are using methylprednisolone injection prior to any laboratory test.

Tell the doctor or technician if you are getting any skin testing, such as allergy or tuberculosis tests, that you are taking methylprednisolone injection.

Do not share your medication with anybody else. Any queries you may have regarding prescription refills should be directed to your chemist.

Ask your chemist any inquiries you may have regarding the injection of methylprednisolone.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.