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Deltasone (Generic Prednisone)

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Why is this medication prescribed?

Deltasone, also known as prednisone, is a corticosteroid medication primarily prescribed to treat various inflammatory conditions, autoimmune disorders, allergic reactions, and certain types of cancer. Here are some common reasons why Deltasone might be prescribed:

  • Inflammatory Conditions: Deltasone is often used to manage inflammation associated with conditions like rheumatoid arthritis, lupus, inflammatory bowel disease (such as Crohn’s disease or ulcerative colitis), and others.
  • Allergic Reactions: It can be prescribed to alleviate severe allergic reactions, such as allergic asthma or anaphylaxis.
  • Asthma: In cases of severe asthma exacerbations, Deltasone may be used to reduce inflammation in the airways and improve breathing.
  • Skin Conditions: Deltasone can help manage various skin conditions like eczema, psoriasis, and dermatitis.
  • Organ Transplants: Following organ transplantation, Deltasone is often prescribed to suppress the immune system and prevent rejection of the transplanted organ.
  • Cancer Treatment: In some cases, Deltasone is used as part of chemotherapy regimens for certain types of cancer, particularly lymphomas and leukemias.

How should this medicine be used?

As for how Deltasone should be used, it’s crucial to follow your healthcare provider’s instructions and the prescription label carefully. Typically, it’s taken orally, with or without food. Here are some general guidelines:

  • Dosage: The dosage will depend on the condition being treated, the severity of the condition, and individual factors. Your doctor will prescribe the appropriate dose.
  • Timing: Deltasone is usually taken once daily, preferably in the morning, to reduce the risk of insomnia or sleep disturbances.
  • Duration: It’s essential not to stop taking Deltasone abruptly, as it can cause withdrawal symptoms. Your doctor will provide instructions on how long you should take the medication and whether the dosage should be tapered off gradually.
  • Monitoring: Regular check-ups with your healthcare provider are necessary to monitor your response to the medication and to watch for any potential side effects.
  • Side Effects: Be aware of potential side effects, which can include weight gain, increased appetite, mood changes, insomnia, fluid retention, and others. Notify your doctor if you experience any concerning side effects.
  • Interactions: Deltasone can interact with other medications, so inform your doctor about all the medications, supplements, and herbal products you are taking.

Always consult your healthcare provider for personalized advice on how to use Deltasone safely and effectively.

Other uses for this medicine

As for other uses, Deltasone may sometimes be prescribed for conditions not listed in the approved professional labeling (off-label uses). However, it’s essential to use it only as directed by your healthcare provider.

What special precautions should I follow?

Regarding precautions for taking Deltasone, it’s essential to follow your healthcare provider’s instructions carefully. Here are some general precautions:

  • Dosage: Take Deltasone exactly as prescribed by your doctor. Do not take more or less than the recommended dose, and do not stop taking it suddenly without consulting your doctor.
  • Duration: Deltasone is often prescribed for short-term use to manage acute conditions. Prolonged use can lead to serious side effects, so your doctor will likely prescribe the lowest effective dose for the shortest duration possible.
  • Side effects: Be aware of potential side effects, including increased risk of infection, elevated blood sugar levels, weight gain, mood changes, and osteoporosis. Report any unusual symptoms to your doctor promptly.
  • Interactions: Deltasone can interact with other medications and supplements. Inform your doctor about all the medications you are currently taking to avoid potential interactions.
  • Medical conditions: Inform your doctor if you have any medical conditions, especially diabetes, hypertension, osteoporosis, or a history of psychiatric disorders, as Deltasone may worsen these conditions or require adjustments in treatment.
  • Pregnancy and breastfeeding: Consult your doctor before taking Deltasone if you are pregnant, planning to become pregnant, or breastfeeding, as it may pose risks to the fetus or nursing infant.

Always communicate openly with your healthcare provider about your medical history, current medications, and any concerns or questions you have about taking Deltasone. They can provide personalized guidance and monitor your progress to ensure safe and effective treatment.

What special dietary instructions should I follow?

  • Dietary considerations: While taking Deltasone, you may need to monitor your salt and potassium intake, especially if you have conditions like hypertension or heart disease. Your doctor may recommend a diet low in sodium and high in potassium-rich foods, such as fruits and vegetables.
  • Alcohol: Limit or avoid alcohol consumption while taking Deltasone, as it can increase the risk of certain side effects and may interfere with the medication’s effectiveness.

What should I do if I forget a dose?

  • Take it as soon as you remember: If you miss a dose, take it as soon as you remember. However, if it’s almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule.
  • Do not double up: Do not take a double dose to make up for a missed one, as this can increase the risk of side effects.
  • Notify your doctor: If you frequently forget doses or have difficulty adhering to your medication schedule, inform your doctor. They can provide guidance or suggest strategies to help you stay on track with your treatment plan.

What side effects can this medication cause?

Deltasone (prednisone), like other corticosteroid medications, can cause a range of side effects, which can vary depending on factors such as the dosage, duration of treatment, and individual susceptibility. Some common side effects of Deltasone include:

  • Increased appetite and weight gain: Corticosteroids can stimulate appetite and lead to weight gain, particularly in the abdomen and face.
  • Fluid retention: Deltasone can cause fluid retention, leading to swelling in the legs, ankles, or other parts of the body.
  • Mood changes: Some individuals may experience mood swings, irritability, anxiety, or depression while taking Deltasone.
  • Insomnia: Difficulty falling asleep or staying asleep is a common side effect of corticosteroids.
  • Increased risk of infections: Deltasone can suppress the immune system, increasing the risk of infections. This can include bacterial, viral, fungal, or parasitic infections.
  • Gastrointestinal issues: Side effects such as stomach irritation, ulcers, and increased risk of gastrointestinal bleeding may occur, particularly with long-term use.
  • High blood sugar levels: Corticosteroids can cause insulin resistance and lead to elevated blood sugar levels, which may worsen diabetes or predispose individuals to developing diabetes.
  • Osteoporosis and bone fractures: Long-term use of Deltasone can weaken bones and increase the risk of osteoporosis and bone fractures.
  • Cataracts and glaucoma: Prolonged use of corticosteroids may increase the risk of developing cataracts and glaucoma, leading to vision problems.
  • Adrenal suppression: Deltasone can suppress the adrenal glands’ natural production of cortisol, particularly with long-term use or high doses. This can lead to adrenal insufficiency, where the body is unable to produce enough cortisol on its own.
  • Skin changes: Corticosteroids can cause thinning of the skin, easy bruising, and increased susceptibility to skin infections.
  • Muscle weakness: Some individuals may experience muscle weakness or wasting with prolonged use of Deltasone.

These are not the only potential side effects of Deltasone, and individuals may experience other adverse reactions. It’s essential to discuss any concerns or symptoms with your healthcare provider, who can provide guidance and adjust your treatment plan if necessary. Additionally, the benefits of Deltasone in managing your condition should be weighed against the potential risks of side effects.

What should I know about storage and disposal of this medication?

When it comes to storage and disposal of Deltasone (prednisone), here’s what you should know:


  • Store at room temperature: Keep Deltasone tablets at room temperature away from moisture, heat, and light.
  • Keep out of reach of children and pets: Store Deltasone in a secure location where children and pets cannot access it.
  • Avoid bathroom storage: Do not store Deltasone in the bathroom, as moisture and humidity can degrade the medication.
  • Follow specific instructions: Follow any specific storage instructions provided by your pharmacist or healthcare provider.


  • Do not flush down the toilet: Do not flush Deltasone tablets down the toilet unless instructed to do so by your pharmacist or local waste disposal authorities.
  • Proper disposal: Dispose of unused or expired Deltasone tablets according to local regulations. You can check with your pharmacist or local waste disposal authorities for guidance on proper disposal methods.

In case of emergency/overdose

  • Seek medical attention: If you suspect an overdose of Deltasone, contact your local poison control center or emergency room immediately.
  • Symptoms of overdose: Symptoms of Deltasone overdose may include confusion, dizziness, fainting, rapid or irregular heartbeat, seizures, and difficulty breathing.

What other information should I know?

  • Regular follow-up: Attend all scheduled appointments with your healthcare provider for regular monitoring of your condition and response to Deltasone treatment.
  • Medication interactions: Inform your healthcare provider about all medications, supplements, and herbal remedies you are taking, as Deltasone can interact with certain drugs.
  • Lab tests: Your doctor may order periodic blood tests to monitor for any adverse effects of Deltasone, such as changes in blood sugar levels, electrolyte imbalances, or bone density loss.
  • Avoid sudden discontinuation: Do not stop taking Deltasone abruptly without consulting your doctor, as sudden discontinuation can lead to withdrawal symptoms or adrenal insufficiency.
  • Medical alert: Consider wearing a medical alert bracelet or carrying a medical alert card indicating that you are taking corticosteroids like Deltasone, especially if you have a chronic condition or are at risk of adrenal insufficiency.
  • Pregnancy and breastfeeding: Consult your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding, as Deltasone may pose risks to the fetus or nursing infant.

Always follow your healthcare provider’s instructions and guidance regarding the use, storage, and disposal of Deltasone, and never hesitate to ask questions if you need clarification or assistance.

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