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Why is this medication prescribed?

Deflazacort is a corticosteroid medication primarily prescribed to treat various inflammatory conditions, autoimmune disorders, and allergic reactions. Some of the specific conditions it may be used for include:

  • Muscle disorders: Deflazacort is often prescribed for Duchenne muscular dystrophy (DMD), a genetic disorder characterized by progressive muscle degeneration and weakness.
  • Rheumatic disorders: It can be used to manage symptoms of rheumatoid arthritis, ankylosing spondylitis, and other inflammatory joint conditions.
  • Allergic reactions: Deflazacort may be prescribed to alleviate symptoms of severe allergies, such as allergic rhinitis or asthma exacerbations.
  • Inflammatory skin conditions: It can help reduce inflammation and itching associated with conditions like eczema and dermatitis.
  • Autoimmune diseases: Deflazacort may be used to suppress the immune system in conditions such as lupus or autoimmune hepatitis.

How should this medicine be used?

As for how Deflazacort should be used, it’s crucial to follow your healthcare provider’s instructions and the prescription label carefully. Here are some general guidelines:

  • Dosage: The dosage of Deflazacort varies depending on the condition being treated, its severity, and individual patient factors. It’s typically taken once daily, usually in the morning.
  • Duration: Treatment duration may also vary. It’s important not to stop taking Deflazacort abruptly unless directed by your doctor, as sudden discontinuation can lead to withdrawal symptoms or a flare-up of the underlying condition.
  • Administration: Deflazacort is usually taken orally, with or without food. It’s essential to swallow the tablets whole and not crush, chew, or break them unless your doctor advises otherwise.
  • Monitoring: Your doctor may periodically adjust your dosage based on your response to the medication and any side effects you experience. Regular monitoring of your condition and laboratory tests may be necessary.
  • Caution: Long-term use of corticosteroids like Deflazacort can lead to various side effects, including bone thinning (osteoporosis), increased risk of infections, high blood pressure, and mood changes. It’s essential to discuss the risks and benefits of treatment with your healthcare provider.

Always communicate with your healthcare provider about any concerns or questions you have regarding your medication regimen, including Deflazacort. They can provide personalized guidance based on your specific health needs.

Other uses for this medicine

  • Duchenne Muscular Dystrophy (DMD): Deflazacort is also used to treat Duchenne muscular dystrophy in children older than 5 years of age. It helps to improve muscle strength and function in these patients.
  • Allergic Reactions: Deflazacort can be prescribed to manage severe allergic reactions or allergic conditions like hay fever or allergic asthma when other treatments have not been effective.

What special precautions should I follow?

When taking Deflazacort, there are several special precautions to keep in mind:

  • Regular Monitoring: Your doctor will likely schedule regular check-ups and may perform blood tests to monitor for any potential side effects, such as changes in blood sugar, potassium levels, or bone density.
  • Avoid Abrupt Discontinuation: As with any corticosteroid medication, it’s crucial not to stop taking Deflazacort suddenly without your doctor’s guidance. Abrupt discontinuation can lead to withdrawal symptoms or a flare-up of the underlying condition.
  • Immunosuppression: Deflazacort can suppress the immune system, increasing susceptibility to infections. It’s essential to avoid close contact with individuals who have contagious illnesses, and to promptly report any signs of infection to your doctor.
  • Bone Health: Long-term use of corticosteroids like Deflazacort can weaken bones and increase the risk of osteoporosis. Your doctor may recommend measures to help protect bone health, such as calcium and vitamin D supplements, weight-bearing exercise, and possibly medication to prevent bone loss.
  • Psychiatric Effects: Corticosteroids can sometimes cause mood changes, including irritability, anxiety, or depression. If you experience significant mood changes while taking Deflazacort, it’s essential to discuss them with your doctor.

Always adhere to your healthcare provider’s recommendations and inform them of any other medications, supplements, or health conditions you have, as they can affect how Deflazacort works and its potential side effects.

What special dietary instructions should I follow?

Regarding special dietary instructions, there are no specific dietary restrictions associated with Deflazacort. However, it’s generally advisable to maintain a balanced diet rich in fruits, vegetables, whole grains, and lean proteins. If you have specific dietary concerns or restrictions, discuss them with your healthcare provider or a registered dietitian.

What should I do if I forget a dose?

If you forget to take a dose of Deflazacort, take it as soon as you remember, unless it’s almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you’re unsure about what to do, consult your doctor or pharmacist for guidance. It’s important to try to maintain a consistent schedule with this medication for optimal effectiveness.

What side effects can this medication cause?

Deflazacort, like other corticosteroid medications, can cause a range of side effects, though not everyone will experience them, and their severity can vary. Common side effects may include:

  • Gastrointestinal Issues: These can include stomach upset, nausea, vomiting, and abdominal pain.
  • Weight Gain: Corticosteroids can lead to fluid retention and increased appetite, which may result in weight gain.
  • Changes in Mood: Some individuals may experience mood swings, irritability, anxiety, or depression while taking Deflazacort.
  • Insomnia: Difficulty falling asleep or staying asleep may occur, particularly if the medication is taken later in the day.
  • Increased Risk of Infections: Deflazacort can suppress the immune system, increasing the risk of infections. This can include common infections like colds, as well as more serious infections.
  • Skin Changes: Some individuals may experience changes in skin appearance, such as thinning, easy bruising, or increased susceptibility to acne.
  • Fluid Retention: Swelling (edema) in the extremities can occur due to fluid retention.
  • Osteoporosis and Bone Fractures: Long-term use of corticosteroids like Deflazacort can weaken bones and increase the risk of osteoporosis and fractures.
  • Glaucoma and Cataracts: Prolonged corticosteroid use may increase the risk of developing glaucoma or cataracts.
  • Hypertension (High Blood Pressure): Corticosteroids can cause an increase in blood pressure, which may require monitoring and management.
  • Hyperglycemia (High Blood Sugar): Deflazacort can raise blood sugar levels, particularly in individuals with diabetes or prediabetes.
  • Adrenal Suppression: Prolonged use of corticosteroids can suppress the body’s natural production of cortisol, leading to adrenal insufficiency.
  • Growth Suppression (in children): Long-term use of corticosteroids can interfere with growth and development in children.

It’s important to discuss any concerns about potential side effects with your healthcare provider. They can provide guidance on managing side effects and may adjust your treatment plan if necessary to minimize their impact. Additionally, if you experience any severe or concerning side effects while taking Deflazacort, seek medical attention promptly.

What should I know about storage and disposal of this medication?

When it comes to the storage and disposal of Deferiprone:


  • Store Deflazacort at room temperature away from light and moisture.
  • Keep the medication out of reach of children and pets.
  • Do not store Deflazacort in the bathroom or near the kitchen sink where it might get damp.


  • Dispose of expired or unused Deflazacort tablets properly according to local guidelines or by consulting your pharmacist.
  • Do not flush medications down the toilet unless instructed to do so. Instead, dispose of them in a sealed plastic bag or container with household trash.

In case of emergency/overdose

  • In case of an overdose, seek emergency medical attention or contact a poison control center immediately.
  • Symptoms of overdose may include excessive drowsiness, confusion, rapid breathing, fainting, or seizures.

What other information should I know?

  • Inform all your healthcare providers, including doctors, dentists, and pharmacists, that you are taking Deflazacort. This includes disclosing any other medications, supplements, or herbal products you are using.
  • Keep a list of all your medications and their dosages for reference, and carry it with you at all times.
  • Attend all scheduled appointments with your doctor for monitoring of your condition and response to treatment.
  • Do not share Deflazacort with others, even if they have similar symptoms or conditions, as it may not be appropriate or safe for them.
  • If you have any questions or concerns about Deflazacort or its use, do not hesitate to discuss them with your healthcare provider or pharmacist.

By following these guidelines, you can ensure the safe and effective use of Deflazacort while minimizing the risk of adverse effects or complications.

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