The goserelin implant is used both alone to treat the symptoms of advanced prostate cancer and in conjunction with radiation therapy and other drugs to treat localised prostate cancer. In certain women, it is also used to treat advanced breast cancer. Moreover, it is used to treat abnormal uterine bleeding as well as endometriosis, a condition in which the tissue that lines the uterus (womb) develops in other parts of the body and causes pain, heavy or irregular menstruation (periods), and other symptoms. A group of drugs known as gonadotropin-releasing hormone (GnRH) agonists includes the goserelin implant. It functions by lowering the body’s levels of specific hormones.

Goserelin is available as an implant that a doctor or nurse will place in your stomach area using a syringe subcutaneously (under the skin) in a hospital or medical facility. Every four weeks, a 3.6 mg goserelin implant is typically placed. Every 12 weeks, a 10.8 mg goserelin implant is typically placed. The ailment being treated and how you react to the drug will determine how long you need to receive treatment. How long you should utilise the goserelin implant is something your doctor will decide.

In the initial weeks following implant installation, goserelin may cause an increase in specific hormones. At this period, your doctor will keep a close eye on you for any new or worsening symptoms.

Ask your doctor or chemist for more details if you believe this drug should be used for something else.

Before receiving goserelin implant,

• If you have an allergy to goserelin, histrelin (Supprelin LA, Vantas), leuprolide (Eligard, Lupron), nafarelin (Synarel), triptorelin (Trelstar), any other drugs, or any of the chemicals in goserelin implant, let your doctor and chemist know right away. Get a list of the ingredients from your chemist.
• Inform your doctor and chemist about any additional prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products you are now taking or intend to use. Incorporate any of the following: drugs for seizures or oral steroids such prednisone, methylprednisolone, and dexamethasone (Decadron, Dexpak) (Sterapred). Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects.
• Inform your physician if you have a history of heavy alcohol or tobacco use, if you or a family member has ever experienced osteoporosis (a condition in which the bones become brittle and prone to fracture), if you are currently experiencing or have ever experienced diabetes, unusual vaginal bleeding, urinary obstruction in men (a blockage that makes it difficult to urinate), or if you have heart or liver disease.
• If you are pregnant or plan to become pregnant, let your doctor know. Except for the treatment of advanced breast cancer, goserelin implants shouldn’t be administered to pregnant women. If you suspect that you become pregnant while receiving treatment, call your doctor straight once. The foetus could suffer from a goserelin implant. While utilising a goserelin implant or for 12 weeks afterward, you shouldn’t plan to get pregnant. To ensure that you are not pregnant when you start using goserelin implant, your doctor may do a pregnancy test or advise you to start your therapy during your period. While utilising the goserelin implant and for 12 weeks following your treatment, you must utilise a trustworthy nonhormonal method of birth control to avoid getting pregnant. Even if you shouldn’t experience regular menstrual cycles while receiving treatment, discuss the best birth control methods with your doctor and keep using it. Inform your doctor if you are nursing a baby. Breastfeeding is not advised while receiving goserelin implant treatment.

Keep eating normally unless your doctor instructs you otherwise.

Call your doctor as soon as possible to reschedule your appointment if you need to get a goserelin implant but miss your scheduled appointment. Within a few days, provide the missed dose.

Side effects from goserelin implant are possible. If any of these symptoms are severe or do not go away, let your doctor know right once:

• Headache
• Hot flash (a sudden wave of mild or intense body heat)
• Sweating
• Abrupt facial, upper chest, or neck redness
• Not enough energy
• Reduced appetite
• Women who have breast pain or breast size changes
• Reduced sexual inclination or capacity
• Painful sexual activity
• Discharge, dryness, or irritation from the vagina
• Menstruation (periods)
• Edoema of the lower legs, ankles, feet, or hands
• Depression
• Nervousness
• Lack of emotional control and frequent mood swings
• Having trouble falling or staying asleep
• At the site where the implant was placed, there may be pain, itching, swelling, or redness.

Certain adverse effects can be very harmful. Call your doctor right away if any of these symptoms occur to you:

• Hives
• Rash
• Itching
• Breathing or swallowing challenges
• Chest ache
• Arm, back, neck, or jaw discomfort
• Unexpected weight gain
• Slow or challenging speech
• Nausea or fainting
• Arm or leg that is weak or numb
• Bone ache
• Inability to move legs
• Difficult or painful urinating
• Excessive urination
• Severe thirst
• Weakness
• Fuzzy vision
• Mouth ache
• Nausea
• Vomiting
• Fruity-smelling breath
• Diminished awareness

Your bones’ density could diminish as a result of the goserelin implant, which could raise your risk of fractures and broken bones. See your doctor to learn more about the dangers associated with taking this drug and what you may do to reduce them.

Further adverse consequences from goserelin implant are possible. If you experience any strange issues while taking this drug, call your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

Keep all of your doctor’s appointments.

Ask any inquiries you may have regarding the goserelin implant to your chemist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.