PrescriptionGiant is a FREE prescription savings program that can save you up to 75% on your prescriptions with or without insurance!

Decadron (Generic Dexamethasone)

Actual product appearance may differ slightly.

Click the CARD below to print or take a screenshot on your mobile phone or tablet. There is no need to download another app!

If you would like to personalize your card enter your full name in the member name field below the card at this link and click the Update button.

Why is this medication prescribed?

Dexamethasone is prescribed for a range of conditions due to their potent anti-inflammatory and immunosuppressive properties. Here’s why dexamethasone tablets might be prescribed:

  • Inflammatory Conditions: Dexamethasone is commonly used to treat inflammatory conditions such as rheumatoid arthritis, lupus, inflammatory bowel disease (Crohn’s disease and ulcerative colitis), and allergic reactions.
  • Asthma: Dexamethasone may be prescribed as a short-term treatment during severe asthma attacks to reduce inflammation in the airways and improve breathing.
  • Skin Conditions: They can be used to manage various skin conditions, including eczema, psoriasis, and dermatitis.
  • Allergic Reactions: Dexamethasone may be prescribed to alleviate severe allergic reactions, including anaphylaxis.
  • Certain Cancers: In some cases, dexamethasone are used as part of cancer treatment to reduce inflammation and swelling, especially in conditions like leukemia and lymphoma.
  • Adrenal Insufficiency: Dexamethasone may be prescribed to replace deficient cortisol levels in people with adrenal insufficiency.

How should this medicine be used?

The dosage and administration can vary depending on the condition being treated, the severity of the condition, and individual patient factors. Generally, Dexamethasone is available in various forms, including tablets, injections, and topical creams. Here are some general guidelines:

  • Dosage: The dosage of Dexamethasone will vary based on the condition being treated. It’s typically prescribed as a short-term treatment, but in some cases, it may be used long-term. Always take the medication exactly as prescribed by your doctor.
  • Administration: Dexamethasone tablets are usually taken orally with a full glass of water. It’s essential to swallow the tablets whole and not crush or chew them unless directed otherwise by your doctor. If you’re using Dexamethasone in another form (such as injections or topical creams), follow the specific instructions provided by your healthcare provider.
  • Timing: Dexamethasone is often taken once daily in the morning to mimic the body’s natural cortisol production rhythm. However, your doctor may prescribe a different dosing schedule based on your individual needs.
  • Duration: The duration of treatment with Dexamethasone will depend on the condition being treated. It’s crucial not to stop taking the medication abruptly without consulting your doctor, as this can lead to withdrawal symptoms or a flare-up of the underlying condition.
  • Monitoring: While taking Dexamethasone, your doctor may schedule regular check-ups to monitor your progress, assess any side effects, and adjust your dosage if necessary. It’s essential to attend these appointments and communicate any concerns or changes in your health to your healthcare provider.
  • Side Effects: Dexamethasone can cause side effects, especially with long-term use or at high doses. These can include increased appetite, weight gain, mood changes, insomnia, high blood pressure, and increased risk of infections. If you experience any troubling symptoms while taking Dexamethasone, contact your doctor promptly.

Remember, Dexamethasone is a potent medication with potential side effects, so it’s crucial to use it under the guidance of a healthcare professional and to follow their instructions carefully.

What special precautions should I follow?

Regarding special precautions for Dexamethasone, it’s essential to be aware of the following:

  • Medical History: Before taking Dexamethasone, inform your doctor about any medical conditions you have, especially diabetes, high blood pressure, osteoporosis, glaucoma, cataracts, infections, or mental health disorders.
  • Pregnancy and Breastfeeding: Dexamethasone should be used during pregnancy only if the potential benefits justify the potential risks to the fetus. It may pass into breast milk and could harm a nursing infant, so consult your doctor if you are pregnant or breastfeeding.
  • Interactions: Dexamethasone can interact with various medications, including certain antibiotics, antifungal drugs, HIV medications, antiseizure medications, and some vaccines. Inform your doctor about all the medications you are taking, including prescription, over-the-counter, herbal supplements, and vitamins.
  • Immune System Suppression: Dexamethasone can suppress the immune system, increasing the risk of infections. Avoid close contact with people who have contagious illnesses, and promptly report any signs of infection (such as fever, sore throat, or cough) to your doctor.
  • Withdrawal Symptoms: Do not stop taking Dexamethasone suddenly, as it can lead to withdrawal symptoms such as weakness, fatigue, joint pain, and difficulty breathing. Your doctor will gradually taper your dose to minimize these effects when discontinuing the medication.
  • Monitoring: Regular monitoring of blood pressure, blood sugar levels, bone density, and eye health may be necessary while taking Dexamethasone to monitor for potential side effects and complications.

Always follow your doctor’s advice and instructions regarding the use of Dexamethasone and any precautions specific to your individual health circumstances.

What special dietary instructions should I follow?

There are no specific dietary restrictions associated with Dexamethasone use. However, it’s essential to maintain a balanced diet and healthy lifestyle, especially if you have conditions such as diabetes or high blood pressure that may be affected by Dexamethasone. Eating a diet rich in fruits, vegetables, whole grains, and lean proteins can help support overall health and well-being.

What should I do if I forget a dose?

If you miss a dose of Dexamethasone, take it as soon as you remember. However, if it’s almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double up on doses to make up for a missed one.

What side effects can this medication cause?

Dexamethasone, like any medication, can cause side effects, although not everyone experiences them. The likelihood and severity of side effects can vary depending on factors such as the dosage, duration of use, and individual health characteristics. Some common side effects of Dexamethasone include:

  • Increased Appetite and Weight Gain: Dexamethasone can stimulate appetite, leading to increased food intake and weight gain, particularly with long-term use.
  • Fluid Retention: Some individuals may experience fluid retention, resulting in swelling of the face, hands, ankles, or feet.
  • Mood Changes: Dexamethasone can affect mood and behavior, leading to irritability, agitation, anxiety, or depression in some people.
  • Insomnia: Difficulty sleeping or insomnia is a common side effect of Dexamethasone, particularly when taken in higher doses or late in the day.
  • Gastrointestinal Symptoms: Dexamethasone can irritate the stomach lining, leading to symptoms such as indigestion, heartburn, nausea, or abdominal discomfort.
  • Increased Blood Sugar Levels: Dexamethasone can raise blood sugar levels, particularly in individuals with diabetes or those predisposed to diabetes. This can worsen glycemic control and may require adjustments in diabetes medications.
  • High Blood Pressure: Long-term use of Dexamethasone can elevate blood pressure, increasing the risk of hypertension and related complications.
  • Osteoporosis and Bone Fractures: Prolonged use of Dexamethasone can weaken bones, leading to osteoporosis and an increased risk of fractures, particularly in postmenopausal women.
  • Suppression of the Immune System: Dexamethasone suppresses the immune system, making individuals more susceptible to infections and delaying wound healing.
  • Cataracts and Glaucoma: Long-term use of Dexamethasone, particularly when administered topically or in high doses, can increase the risk of developing cataracts or glaucoma.
  • Skin Changes: Dexamethasone can cause skin thinning, easy bruising, acne, or excessive hair growth (hirsutism).
  • Adrenal Insufficiency: Prolonged use of Dexamethasone can suppress the body’s natural cortisol production, leading to adrenal insufficiency when the medication is discontinued.

It’s important to report any concerning or persistent side effects to your healthcare provider promptly. They can provide guidance on managing side effects and may adjust your treatment regimen if necessary. Additionally, do not stop taking Dexamethasone suddenly without consulting your doctor, as this can lead to withdrawal symptoms or a flare-up of the underlying condition.

What should I know about storage and disposal of this medication?

When it comes to the storage and disposal of Dexamethasone, it’s essential to follow these guidelines:


  • Store Dexamethasone tablets, injections, or other forms as directed by your healthcare provider or pharmacist.
  • Keep Dexamethasone in its original packaging or container to protect it from light, moisture, and heat.
  • Store Dexamethasone at room temperature away from direct sunlight and heat sources.
  • Keep Dexamethasone out of reach of children and pets, as it can be harmful if ingested accidentally.


  • Dispose of unused or expired Dexamethasone properly to prevent accidental ingestion or environmental contamination.
  • Do not flush Dexamethasone down the toilet or pour it down the drain unless instructed to do so by your pharmacist or local waste disposal authorities.
  • Consult your pharmacist or local waste disposal facility for guidance on the proper disposal of Dexamethasone. They may provide specific instructions for medication disposal in your area.

In case of emergency/overdose

  • Seek Immediate Medical Attention: If you suspect an overdose or experience severe symptoms such as rapid heart rate, difficulty breathing, confusion, seizures, or loss of consciousness, call emergency services (such as 911 in the United States) or go to the nearest emergency room immediately.
  • Provide Information: Be prepared to provide information about the type and amount of Dexamethasone ingested, as well as any other medications or substances taken. This information will assist healthcare providers in providing appropriate treatment.
  • Follow Medical Advice: Follow the instructions of healthcare providers for emergency treatment of Dexamethasone overdose. Treatment may involve supportive care to manage symptoms and complications.

What other information should I know?

  • Avoid Abrupt Discontinuation: Do not stop taking Dexamethasone suddenly without consulting your healthcare provider, as this can lead to withdrawal symptoms or a flare-up of the underlying condition. Your doctor will provide guidance on tapering the dose gradually when discontinuing the medication.
  • Regular Monitoring: Your doctor may schedule regular check-ups to monitor your response to Dexamethasone and to check for any side effects or complications. Attend these appointments and communicate any concerns or changes in your health to your healthcare provider.
  • Medical ID: If you are taking Dexamethasone long-term or have a medical condition that requires the use of corticosteroids, consider wearing a medical identification bracelet or necklace to alert healthcare providers in case of emergency.
  • Avoid Alcohol and NSAIDs: Limit or avoid alcohol consumption while taking Dexamethasone, as it can increase the risk of gastrointestinal bleeding and other complications. Additionally, avoid nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen or aspirin unless directed by your doctor, as they can increase the risk of gastrointestinal ulcers and bleeding when used with Dexamethasone.
  • Follow Dietary Recommendations: Maintain a balanced diet and healthy lifestyle while taking Dexamethasone. Your doctor may recommend dietary modifications or supplements to address specific nutritional needs or minimize side effects.

Always consult your healthcare provider or pharmacist if you have any questions or concerns about the storage, disposal, administration, or potential risks associated with Dexamethasone.

Copyright © 2023