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DaunoXome (Generic Daunorubicin Lipid Complex Injection)

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WARNING

Daunorubicin lipid complex injection must be administered under the care of a physician with training in administering chemotherapy drugs for cancer.

Any time throughout your therapy or months to years after it has stopped, daunorubicin lipid complex may result in significant or life-threatening heart issues. In order to determine whether your heart is functioning properly enough for you to safely receive daunorubicin lipid complex, your doctor will prescribe tests both before and during your therapy. These tests could involve an electrocardiogram (ECG), which records the electrical activity of the heart, and an echocardiogram, which gauges the heart’s capacity to pump blood using sound waves. If tests reveal that your heart’s capacity to pump blood has deteriorated, your doctor could advise against taking this drug. If you have or have previously had a form of heart illness or radiation (x-ray) therapy to the chest area, let your doctor know. If you use or have ever taken certain cancer chemotherapy drugs including doxorubicin (Doxil), epirubicin (Ellence), idarubicin (Idamycin), mitoxantrone (Novantrone), cyclophosphamide (Cytoxan), or trastuzumab, let your doctor and pharmacist know (Herceptin). Call your doctor right away if you have any of the following symptoms: breathing difficulties, hand, foot, ankle, or lower leg edoema, or a rapid, erratic, or pounding heartbeat.

The amount of blood cells in your bone marrow may drastically decrease as a result of daunorubicin lipid complex. This could result in specific symptoms and raise your risk of getting a serious infection. Call your doctor right away if you have any of the following symptoms: various symptoms of infection, such as a fever, chills, sore throat, persistent coughing, and congestion.

If you have liver illness now or ever had it, let your doctor know. If you have liver problems, your doctor might need to change your dose.

Within the first five minutes of your infusion, you can have a reaction to a dosage of daunorubicin lipid complex injection. If you suffer chest tightness, flushing, or back pain while receiving daunorubicin lipid complex, call your doctor right away.

Keep all of your appointments with your physician and the lab. To determine how your body is reacting to the daunorubicin lipid complex, your doctor will prescribe a number of tests.

Why is this medication prescribed?

Advanced Kaposi’s sarcoma, a form of cancer that results in the growth of abnormal tissue in various places of the body, is treated with the drug daunorubicin lipid complex (AIDS). The drug daunorubicin lipid complex belongs to the anthracycline drug class. The growth of cancer cells in your body is slowed or stopped by it.

How should this medicine be used?

A doctor or nurse will administer the daunorubicin lipid complex intravenously (into a vein) over the course of an hour in a medical setting. Usually, it’s administered once every two weeks.

For a copy of the manufacturer’s information for the patient, ask your chemist or doctor.

Other uses for this medicine

Ask your doctor or chemist for more details if you believe this drug should be used for something else.

What special precautions should I follow?

Before receiving daunorubicin lipid complex,

  • If you have an allergy to daunorubicin, any other medications, or any of the chemicals in daunorubicin injection, let your doctor and chemist know right once. Get a list of the components from your pharmacist.
  • Inform your doctor and chemist about any additional prescription and over-the-counter medications, vitamins, herbal items, nutritional supplements, and other drugs you are now taking or intend to take. Mention any of the following medications, as well as the ones in the IMPORTANT WARNING section: azathioprine (Imuran), cyclosporine (Neoral, Sandimmune), methotrexate (Rheumatrex, Trexall), sirolimus (Rapamune), and tacrolimus (Prograf). Your doctor might need to adjust your medication doses or keep a close eye out for any negative side effects.
  • Inform your doctor if you currently have kidney disease or have ever had it.
  • If you are expecting a child, intend to get pregnant, or are a nursing mother, let your doctor know. While getting daunorubicin lipid complex, you shouldn’t get pregnant. Call your physician if you conceive while taking daunorubicin lipid combination. The foetus might be harmed by the daunorubicin lipid complex.

What special dietary instructions should I follow?

Keep eating normally unless your doctor instructs you otherwise.

What side effects can this medication cause?

Side effects from daunorubicin lipid complex are possible. If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Nausea
  • Vomiting
  • Mouth- and throat-related sores
  • Diarrhoea
  • Abdominal pain
  • Constipation
  • Hair fall

Certain adverse effects can be very harmful. Call your doctor right away if you have any of these signs or any of those in the IMPORTANT CAUTION section:

  • Redness, discomfort, swelling, or burning at the injection site
  • Rash
  • Hives
  • Itching

Further negative effects from daunorubicin lipid complex are possible. If you experience any strange issues while taking this medicine, contact your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

In case of emergency/overdose

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Moreover, information can be found online at https://www.poisonhelp.org/help. Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

Overdose signs could include the following:

  • Nausea
  • Vomiting
  • Extreme fatigue
  • Fever, persistent cough and congestion, sore throat, or other indicators of illness

What other information should I know?

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • DaunoXome®
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