Pregnant women and anyone who could become pregnant should avoid taking danazol. The foetus might suffer from danazol. Before starting this medicine, you must have a negative pregnancy test. In order to ensure that you are not pregnant, start taking this medicine during your period. During your therapy, use a reliable method of contraception. You shouldn’t use hormonal contraceptives as your sole method of birth control while receiving therapy with danazol since they may lessen their effectiveness (birth control pills, patches, rings, implants, or injections). You must also practise barrier birth control (device that blocks sperm from entering the uterus such as a condom or a diaphragm). Ask your doctor to assist you in selecting a birth control technique that will be effective for you. Danazol can cause pregnancy, so call your doctor right once if it does.

A blood clot that could result in a heart attack or stroke could form in your arms, legs, lungs, heart, or brain if you take danazol. If you have or have ever had a blood clot, let your doctor know. Call your doctor right away if you have any of the following symptoms: Leg that is warm, red, swollen, or sensitive; speech or comprehension difficulties; paralysis or numbness in the face, arm, or leg; an unexpectedly intense headache; and sudden changes in vision, hazy or blackened vision, or the perception of a second person.

Those who use danazol for an extended period of time run the risk of developing liver damage and gastrointestinal haemorrhage. If you have liver illness now or ever had it, let your doctor know. Call your doctor right away if you have any of the following symptoms: skin or eye yellowing, stomach ache, excessive fatigue, or unusual bleeding or bruising.

Danazol may increase the pressure inside the skull’s cavity. Danazol should be stopped immediately if you suffer any of the following symptoms and you should consult a physician: headaches, motion sickness, nausea, or vision issues.

Keep all of your appointments with your physician and the lab. To monitor how your body is responding to danazol, your doctor may request specific lab tests both before and after therapy.

The dangers of taking danazol should be discussed with your doctor.

Endometriosis can be treated with danazol (a condition in which the type of tissue that lines the uterus [womb] grows in other areas of the body and causes infertility, pain before and during menstrual periods, pain during and after sexual activity, and heavy or irregular bleeding). When other therapies are unsuccessful, danazol is also used to treat fibrocystic breast disease, which is characterised by swollen, sensitive breasts with noncancerous tumours. Danazol is moreover utilised by those with hereditary angioedema to stop attacks (inherited condition that causes episodes of swelling in the hands, feet, face, airway, or intestines). Danazol belongs to the group of drugs known as androgenic hormones. By reducing the size of the displaced uterine tissue, it effectively treats endometriosis. By preventing the release of hormones that cause breast pain and lumps, it effectively treats fibrocystic breast disease. It functions to cure hereditary angioedema by boosting the body’s supply of a natural chemical.

Danazol is available as a capsule to be swallowed. For endometriosis or fibrocystic breast disease, it is typically given twice daily; for hereditary angioedema, it may be used twice or three times daily. Ask your doctor or chemist to explain any instructions on your prescription label that you are unsure about following. Danazol should be taken as prescribed. Never take it in larger or less amounts or more frequently than directed by your doctor.

Don’t stop taking danazol without first consulting your physician. Breast lumps should disappear after 4 to 6 months of treatment if you have fibrocystic breast disease; breast discomfort and tenderness often get better during the first month of taking danazol and disappear after 2 to 3 months.

Moreover, idiopathic thrombocytopenic purpura is occasionally treated with danazol (ITP; an ongoing condition that may cause easy bruising or bleeding due to an abnormally low number of platelets in the blood). The dangers of using this drug for your illness should be discussed with your doctor.

Ask your doctor or chemist for more details if you believe this drug should be used for something else.

Before taking danzaol,

• If you have an allergy to danazol, any other drugs, or any of the substances in danazol capsules, let your doctor and pharmacist know right away. Get a list of the ingredients from your chemist.
• Inform your doctor and chemist about all prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products that you are now taking or intend to use. Incorporate any of the following: Warfarin (Coumadin, Jantoven), atorvastatin (Lipitor, in Caduet), carbamazepine (Carbatrol, Equetro, Tegretol, others), cyclosporine (Gengraf, Neoral, Sandimmune), insulin, lovastatin (Altoprev), simvastatin (Zocor, in Vytorin), or tacrolimus are examples of anticoagulants (‘blood thinner (Astagraf, Prograf). Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects.
• Inform your doctor if you suffer from cancer, heart disease, renal disease, or porphyria, an inherited blood disorder that can affect the neurological system or cause difficulties with the skin. Most likely, your doctor will advise against taking danazol.
• Inform your doctor if you are nursing a baby. Don’t breastfeed while receiving danazol therapy.
• If you have or have ever experienced migraine headaches, epilepsy (seizures), diabetes, hypoparathyroidism (a condition in which the body does not make enough parathyroid hormone), high blood pressure, or other blood disorder, let your doctor know.

If you miss a dosage, take it as soon as you recall. If the next dose is soon due, skip the missed one and carry on with your regular dosing plan. To make up for a missing dose, do not take a second one.

Danazol might have negative effects. If any of these symptoms are severe or do not go away, let your doctor know right once:

• Acne
• Shrinkage of breast size
• Gaining weight
• Greasy hair or skin
• Flushing
• Sweating
• Dryness, burning, itching, or bleeding in the vagina
• Nervousness
• Irritability
• Absence, spotting, or a change in the menstrual cycle

Certain adverse effects can be very harmful. Call your doctor right away if you have any of these signs or any of those in the IMPORTANT CAUTION section:

• Increased facial hair, baldness, swollen arms or legs, hoarseness, painful throat, or deepening of voice (in women)
• Skin that is red, peeling, or blistered

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

Keep this medication tightly closed in the original container and out of the reach of children. Keep it away from light, excessive heat, and moisture at room temperature (not in the bathroom).

Unused prescriptions must be disposed of carefully to prevent pets, kids, and other people from ingesting them. You should not, however, dispose of this medication in the toilet. Instead, utilising a medicine take-back programme is the easiest approach to get rid of your medication. To find out about take-back programmes in your area, speak with your chemist or the garbage/recycling agency in your city. If you do not have access to a take-back programme, see the FDA’s Safe Disposal of Medications website at http://goo.gl/c4Rm4p for additional information.

Although many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Always lock safety caps and promptly stash medication up and away from young children where it is out of their sight and reach to prevent poisoning. http://www.upandaway.org

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Moreover, information can be found online at https://www.poisonhelp.org/help. Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

Inform the lab staff and your doctor that you are taking danazol prior to any laboratory test.

No one else should take your medication. Any queries you may have regarding prescription refills should be directed to your chemist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.