WARNING

Dalteparin injection is an anticoagulant medication used to prevent blood clots in conditions like deep vein thrombosis (DVT) and pulmonary embolism. However, like any medication, it carries certain risks:

• Bleeding: Dalteparin can increase the risk of bleeding, including serious or life-threatening bleeding. This risk is higher in certain individuals, such as those with a history of bleeding disorders or those taking other blood-thinning medications.
• Thrombocytopenia: Dalteparin can cause a decrease in platelet count, which may lead to a condition called thrombocytopenia. This can increase the risk of bleeding or bruising.
• Allergic reactions: Some people may experience allergic reactions to Dalteparin, which can range from mild skin rashes to severe anaphylaxis.
• Heparin-induced thrombocytopenia (HIT): In rare cases, Dalteparin can trigger an immune response that leads to a dangerous decrease in platelet count and an increased risk of blood clots.
• Osteoporosis: Long-term use of Dalteparin may increase the risk of osteoporosis or bone fractures, especially in older adults.
• Injection site reactions: Some individuals may experience pain, irritation, or bruising at the injection site.

It’s important for patients taking Dalteparin to be aware of these risks and to closely follow their healthcare provider’s instructions for dosage and monitoring. Any unusual symptoms or side effects should be reported to a doctor promptly.

Why is this medication prescribed?

Dalteparin injection is a medication prescribed primarily to prevent blood clots from forming after certain types of surgery or during bed rest. It belongs to a class of medications called low molecular weight heparins, which work by decreasing the clotting ability of the blood.

Typically, Dalteparin injection is used in situations where there is a risk of blood clots forming, such as after surgery, during certain medical conditions like deep vein thrombosis (DVT) or pulmonary embolism (PE), or in conditions where mobility is limited for an extended period.

How should this medicine be used?

Here’s how Dalteparin injection is typically used:

• Dosage: The dosage of Dalteparin varies depending on the condition being treated and individual factors such as weight and kidney function. Your healthcare provider will determine the appropriate dosage for you.
• Administration: Dalteparin is usually injected subcutaneously (under the skin). It’s important to follow your healthcare provider’s instructions carefully for the correct injection technique.
• Frequency: The frequency of injections also depends on the condition being treated and the specific dosage prescribed. It’s typically administered once or twice daily.
• Site of Injection: Common sites for injection include the abdomen, thigh, or upper arm. Rotate injection sites to minimize irritation or bruising.
• Duration of Treatment: The duration of treatment with Dalteparin varies depending on the reason for its use. It may be prescribed for a short period (such as during hospitalization) or for longer-term use to prevent recurrent blood clots.
• Monitoring: While taking Dalteparin, your healthcare provider may monitor certain blood tests, such as platelet counts and activated partial thromboplastin time (aPTT), to ensure that the medication is working effectively and not causing adverse effects.

Always use Dalteparin exactly as prescribed by your healthcare provider and never change your dosage without consulting them first. If you have any questions or concerns about how to use Dalteparin, don’t hesitate to ask your healthcare provider or pharmacist for clarification.

Other uses for this medicine

• Preventing Blood Clots: Dalteparin is primarily used to prevent blood clots, especially in conditions like deep vein thrombosis (DVT) or pulmonary embolism (PE).
• Treatment of Blood Clots: In some cases, dalteparin may also be used to treat existing blood clots, although this is typically done in a hospital setting under close medical supervision.
• Prevention of Blood Clots in Certain Medical Conditions: Dalteparin might be prescribed to prevent blood clots in people with certain medical conditions that increase their risk, such as atrial fibrillation or certain types of heart disease.

What special precautions should I follow?

Regarding special precautions for Dalteparin injection, here are some important points to keep in mind:

• Bleeding risk: Dalteparin is an anticoagulant, meaning it can increase the risk of bleeding. It’s crucial to inform your healthcare provider if you have any conditions that may predispose you to bleeding, such as a history of bleeding disorders, gastrointestinal ulcers, or recent surgery.
• Monitoring: Regular monitoring of blood tests, such as platelet counts and activated partial thromboplastin time (aPTT), may be necessary to ensure that the medication is working effectively and not causing excessive anticoagulation.
• Interactions: Inform your healthcare provider about all medications, supplements, and herbal products you are taking, as they may interact with Dalteparin and affect its effectiveness or increase the risk of bleeding.
• Injection technique: Proper injection technique is essential to minimize the risk of bruising, bleeding, or infection. Your healthcare provider will provide instructions on how to correctly administer Dalteparin injections.
• Pregnancy and breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits of using Dalteparin with your healthcare provider. Dalteparin may be used during pregnancy if the potential benefits outweigh the risks, but it should be used with caution and under medical supervision.
• Allergic reactions: Inform your healthcare provider if you have a history of allergies to heparin or any other medications. Allergic reactions to Dalteparin are rare but can occur.

Always follow your healthcare provider’s instructions carefully when using Dalteparin injection and promptly report any unusual symptoms or side effects.

What special dietary instructions should I follow?

Regarding special dietary instructions for Dalteparin injection, there are typically no specific dietary restrictions associated with its use. However, it’s essential to maintain a balanced diet and avoid excessive intake of foods high in vitamin K, as vitamin K can counteract the anticoagulant effects of Dalteparin. If you have any concerns about your diet while taking Dalteparin, consult your healthcare provider or a registered dietitian for personalized advice.

What should I do if I forget a dose?

If you forget a dose of Dalteparin, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one. If you are unsure about what to do, or if you miss multiple doses, contact your healthcare provider for guidance. It’s essential to maintain consistency with your dosing schedule to ensure the effectiveness of the medication in preventing blood clots.

What side effects can this medication cause?

Dalteparin injection, like any medication, can cause side effects, although not everyone experiences them. Common side effects of Dalteparin may include:

• Bleeding: Since Dalteparin is an anticoagulant, the most common side effect is an increased risk of bleeding. This can manifest as nosebleeds, bleeding gums, easy bruising, or prolonged bleeding from cuts.
• Injection Site Reactions: Pain, redness, or bruising at the injection site can occur. These symptoms are usually mild and resolve on their own.
• Heparin-Induced Thrombocytopenia (HIT): In rare cases, Dalteparin can cause a condition called heparin-induced thrombocytopenia, where the body’s immune system produces antibodies against platelets, leading to a decrease in platelet count and an increased risk of blood clot formation.
• Allergic Reactions: While uncommon, some people may experience allergic reactions to Dalteparin, which can range from mild skin reactions (such as itching or rash) to severe reactions (such as difficulty breathing or anaphylaxis).
• Osteoporosis: Long-term use of Dalteparin may lead to decreased bone density and an increased risk of osteoporosis, especially in older adults or individuals with other risk factors for osteoporosis.
• Other: Other less common side effects may include headache, dizziness, nausea, diarrhea, or hair loss.

It’s essential to report any side effects you experience while taking Dalteparin to your healthcare provider. They can help determine whether the side effects are significant and whether any adjustments to your treatment plan are necessary. Additionally, if you experience signs of severe bleeding, such as unusually heavy or prolonged bleeding, blood in the urine or stool, or coughing up blood, seek medical attention immediately.

What should I know about storage and disposal of this medication?

Storage and Disposal of Dalteparin injections:

• Storage:
  • Store Dalteparin injections in the refrigerator between 36°F to 46°F (2°C to 8°C). Do not freeze.
  • Protect from light. Keep the medication in its original packaging until ready to use.
  • If needed, Dalteparin injections can be stored at room temperature (up to 77°F or 25°C) for up to 30 days. Keep them away from heat and light during this time.
  • Do not use Dalteparin if it has been frozen.
• Disposal:
  • Dispose of used needles and syringes in a puncture-resistant container. Many pharmacies provide sharps disposal containers or offer disposal services.
  • Do not dispose of medications in household trash or flush them down the toilet unless instructed to do so by local guidelines or medication take-back programs.

In case of emergency/overdose

• Signs of Overdose: Excessive bleeding is the primary concern with Dalteparin overdose. Symptoms may include unusual bruising, bleeding gums, nosebleeds, blood in urine or stool, or prolonged bleeding from cuts. Seek immediate medical attention if you suspect an overdose or experience any signs of excessive bleeding.
• Treatment of Overdose: In case of overdose or excessive bleeding, medical professionals may administer treatments to help control bleeding and reverse the effects of Dalteparin. Treatment may include stopping Dalteparin administration, administering specific medications to promote clotting, or providing blood transfusions if necessary.

What other information should I know?

• Regular Monitoring: While using Dalteparin, your doctor will likely monitor your blood clotting parameters regularly to ensure the medication’s effectiveness and safety.
• Follow-up: Attend all scheduled follow-up appointments with your healthcare provider. These visits allow your doctor to assess your response to Dalteparin therapy and make any necessary adjustments to your treatment plan.
• Medical Alert: It’s essential to inform all healthcare providers, including dentists and surgeons, about your Dalteparin use before any medical procedures.
• Travel: If you need to travel with Dalteparin injections, ensure proper storage and carry them in your carry-on luggage when flying.
• Refills: Ensure you have an adequate supply of Dalteparin injections and refill your prescription before running out to avoid interruptions in treatment.

Always consult your healthcare provider or pharmacist if you have any questions or concerns about Dalteparin usage, storage, disposal, or what to do in case of emergency or overdose. Your safety is paramount, and they can provide personalized guidance based on your medical history and current health status.