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Cytarabine Lipid Complex Injection

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WARNING

Cytarabine lipid complex injection must be administered in a hospital or other healthcare institution under the guidance of a physician with training in administering chemotherapy drugs for cancer.

Injection of the cytarabine lipid complex may result in a severe or fatal response. After you take a dosage of cytarabine lipid complex, your doctor will closely monitor you and give you a prescription to stop this reaction. Inform your doctor right once if you encounter any of the following signs or symptoms: vomiting, nausea, a headache, and fever

Why is this medication prescribed?

It is possible to treat lymphomatous meningitis with cytarabine lipid complex (a type of cancer in the covering of the spinal cord and brain). The drug cytarabine lipid complex belongs to the group of drugs known as antimetabolites. It functions by reducing or halting the development of cancer cells within your body.

How should this medicine be used?

A doctor or nurse will administer intrathecally (into the fluid-filled area of the spinal canal) the liquid form of the cytarabine lipid complex over the course of 1 to 5 minutes in a medical setting. At weeks 1, 3, 5, 7, and 9, cytarabine lipid complex is administered in five doses spaced two weeks apart. Four weeks later, five more doses are administered in five separate doses separated four weeks apart (at weeks 13, 17, 21, 25, and 29). The hour following your cytarabine lipid complex injectable dose must be spent lying flat.

For a copy of the manufacturer’s information for the patient, ask your pharmacist or doctor.

Other uses for this medicine

Ask your doctor or pharmacist for more details if you believe this drug should be used for something else.

What special precautions should I follow?

Before receiving cytarabine lipid complex injection,

  • If you have a reaction to cytarabine or any of the chemicals in cytarabine lipid complex injection, inform your doctor and pharmacist right away. Request a list of the components from your pharmacist.
  • Inform your doctor and pharmacist about all prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products that you are now taking or intend to use.
  • If you have meningitis, tell your doctor. You won’t likely be prescribed cytarabine lipid complex, according to your doctor.
  • Inform your doctor if you are expecting, intend to get pregnant, or are nursing a baby. While getting cytarabine lipid complex injection, you shouldn’t get pregnant. Call your doctor right away if you get pregnant while taking cytarabine lipid complex. The foetus could suffer from cytarabine lipid complex.

What special dietary instructions should I follow?

Keep eating normally unless your doctor instructs you otherwise.

What side effects can this medication cause?

The lipid complex in cytarabine may have negative effects. If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Diarrhea
  • Constipation
  • Abdominal pain
  • Tiredness
  • Weakness
  • Joint or muscle ache
  • Difficulty sleeping or staying asleep

Some adverse effects can be very harmful. Call your doctor right away or seek emergency medical attention if you develop any of these signs or any of the ones detailed in the IMPORTANT WARNING section:

  • Sudden alteration, loss of hearing or eyesight
  • Dizziness
  • Fainting
  • Confusion or forgetfulness
  • Seizure
  • Tingling, burning, or numbness in the legs, arms, feet, or hands
  • Lack of bladder or bowel control
  • Mobility or feeling on one side of the body is lost
  • Walking difficulty or shaky walking
  • Strong headache, acute fever, and stiff neck
  • Breathing or swallowing challenges
  • Rash
  • Hives
  • Itching
  • Uncommon bruising or bleeding
  • Fever, persistent cough and congestion, sore throat, or other infection-related symptoms

Other negative effects from cytarabine lipid complex are possible. If you experience any strange issues while taking this medicine, contact your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

In case of emergency/overdose

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Additionally, information can be found online at https://www.poisonhelp.org/help. Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

What other information should I know?

Keep all of your appointments with your physician and the lab. To determine how well your body is responding to the cytarabine lipid complex, your doctor will request a few lab tests.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • DepoCyt®
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