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Why is this medication prescribed?

Cyproheptadine treats allergies, hay fever, and airborne irritants that produce red, itchy, watery eyes, sneezing, and runny nose. Additionally, it can be used to treat hives, including those brought on by exposure to cold temperatures and skin rubbing, as well as to soothe the itching associated with allergic skin diseases. When other medications have failed to suppress an allergic reaction’s symptoms, cyproheptadine may be used to treat life-threatening allergic responses in patients who have received blood products as part of their medical care. Cyproheptadine will aid in symptom relief but won’t address the underlying problem or hasten the healing process. Cyproheptadine belongs to the group of drugs known as antihistamines. It functions by preventing the body’s natural histamine from producing the symptoms of allergies.

How should this medicine be used?

Cyproheptadine is available as a liquid solution and tablet for oral use. Typically, it is taken twice or three times day. Every day, take cyproheptadine at around the same time(s). Ask your doctor or pharmacist to explain any instructions on your prescription label that you are unsure about following. Consume cyproheptadine as prescribed. Never take it in larger or less amounts or more frequently than directed by your doctor.

Do not measure your dose if you are using the solution with a regular spoon. Use a spoon made specifically for measuring medication, the measuring cup that came with the medicine, or both.

Other uses for this medicine

Additionally, cyproheptadine is employed in the therapy of migraine headaches as well as Cushing’s syndrome, a disorder brought on by excessive hormones (corticosteroids). Discuss the potential dangers of using this medication for your illness with your doctor.

Other prescriptions for this drug are possible. For more information, consult your physician or pharmacist.

What special precautions should I follow?

Before taking cyproheptadine,

  • If you are allergic to cyproheptadine, other antihistamines, or any other medications, tell your doctor right away.
    Inform your doctor and pharmacist about all prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products that you are now taking or intend to use. Mention any of the following: sedatives, sleeping pills, tranquillizers, narcotic painkillers, muscle relaxants, other drugs for colds or allergies, anxiety, depression, or seizures. Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects.
  • Inform your doctor if you have or have ever had asthma, glaucoma, ulcers, difficulty urinating (due to an enlarged prostate gland), heart disease, high blood pressure, seizures, or an overactive thyroid gland. Glaucoma is a condition in which increased pressure in the eye can cause gradual loss of vision.
  • Inform your doctor if you are expecting, intend to get pregnant, or are nursing a baby. Call your doctor if you become pregnant while taking cyproheptadine.
  • If you are 65 years of age or older, discuss the advantages and disadvantages of taking cyproheptadine with your doctor. Cyproheptadine is typically not recommended for usage in older adults since it is less reliable and less efficient than alternative drugs that can be used to treat the same disease.
  • Inform your doctor or dentist that you are taking cyproheptadine if you are having surgery, including dental surgery.
  • You should be aware that this medicine may cause you to feel sleepy. Prior to understanding how this drug affects you, avoid using machinery or driving a car.
  • The safe consumption of alcohol while taking this medicine should be discussed with your doctor. The negative effects of cyproheptadine can be exacerbated by alcohol.

What special dietary instructions should I follow?

Keep eating normally unless your doctor instructs you otherwise.

What should I do if I forget a dose?

If you miss a dosage, take it as soon as you recall. If the next dose is soon due, skip the missed one and carry on with your regular dosing plan. To make up for a missing dose, do not take a second one.

What side effects can this medication cause?

Cyproheptadine could have negative effects. If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Throat, nose, and mouth are dry
  • Drowsiness
  • Dizziness
  • Nausea
  • Chest discomfort
  • Headache
  • Excitement (especially in children)
  • Muscular tremor

Some adverse effects can be very harmful. Call your doctor right away if you have any of the following symptoms:

  • Having trouble urinating
  • Vision issues
  • Nervousness

Other negative effects of cyproheptadine are possible. If you have any strange side effects while taking this medicine, contact your doctor right once.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep this medication tightly closed in the original container and out of the reach of children. Store it away from excessive heat and moisture at room temperature (not in the bathroom).

Unused prescriptions must be disposed of carefully to prevent pets, kids, and other people from ingesting them. You should not, however, dispose of this medication in the toilet. Instead, utilising a medicine take-back programme is the easiest approach to get rid of your medication. To find out about take-back programmes in your area, speak with your pharmacist or the garbage/recycling department in your city. If you do not have access to a take-back programme, see the FDA’s Safe Disposal of Medicines website at for additional information.

As many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Always lock safety caps and promptly stash medication up and away from young children where it is out of their sight and reach to prevent poisoning.

In case of emergency/overdose

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Additionally, information can be found online at Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

What other information should I know?

Keep all of your doctor’s appointments.

No one else should take your medication. Any queries you may have regarding medication refills should be directed to your pharmacist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • Periactin®
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