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Cyanocobalamin Nasal Gel

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Why is this medication prescribed?

A lack of vitamin B12 may be brought on by any of the following: pernicious anaemia (lack of a natural substance required to absorb vitamin B12 from the intestine); certain illnesses, infections, or medications that reduce the amount of vitamin B12 absorbed from food; or a vegan diet. Cyanocobalamin nasal gel is used to prevent this lack of vitamin B12 (strict vegetarian diet that does not allow any animal products including eggs and dairy products). A deficiency in vitamin B12 can result in lasting nerve damage and anaemia, a condition in which the red blood cells are unable to carry enough oxygen to the organs. B12 injections are required to treat this anaemia. After the red blood cells have stabilised, cyanocobalamin nasal gel can be administered to prevent anaemia and other vitamin B12 deficiency symptoms from reappearing. Additionally, cyanocobalamin nasal gel is used to administer additional vitamin B12 to patients who require particularly high doses of this vitamin due to pregnancy or specific medical conditions. The drug cyanocobalamin nasal gel belongs to the vitamin class of drugs. It can be used to provide vitamin B12 to persons who cannot absorb this vitamin through the intestine since it enters the bloodstream through the nose.

How should this medicine be used?

The gel form of cyanocobalamin is intended for use on the inside of the nose. It is typically utilised once each week. Use the cyanocobalamin nasal gel on the same day of the week each week to make it easier for you to remember to use it. Ask your doctor or pharmacist to explain any instructions on your prescription label that you are unsure about following. As instructed, use cyanocobalamin nasal gel. Use it only as directed by your doctor, neither more nor less often.

Only if you use cyanocobalamin nasal gel frequently will you receive adequate vitamin B12. For the rest of your life, you might need to use cyanocobalamin nasal gel once a week. Even if you feel well, keep using cyanocobalamin nasal gel. Stop taking cyanocobalamin nasal gel only after consulting your physician. Your nerves could suffer if you stop using cyanocobalamin nasal gel since it could cause your anaemia to come back.

Your nose may generate mucus in response to hot foods and beverages, which could wash away the cyanocobalamin nasal gel. One hour before using cyanocobalamin nasal gel and one hour after using this medication, avoid eating or drinking anything hot.

You will be shown how to use cyanocobalamin nasal gel by your doctor or pharmacist. You will also receive printed instructions for using this medication from the manufacturer. If you have any questions, carefully read the material and contact your doctor or pharmacist.

The nasal gel should be applied as follows:

  1. To open both nostrils, softly blow your nose.
  2. Remove the pump’s top by removing the transparent cover.
  3. If this is your first time using the pump, squeeze the finger grips firmly and quickly until you see a drop of gel at the top of the pump. Then apply two more downward pressures to the finger grips.
  4. Insert the pump’s tip about halfway into the nostril. Make sure to direct the tip towards your nose’s back.
  5. One hand should be used to stabilise the pump. Use the fingertip of the opposite hand to press the other nostril shut.
  6. In order to deliver the drug into your nostril, press down hard and fast on the finger grips.
  7. Your nose pump should be removed.
  8. Spend a few seconds massaging the nostril where the drug was placed.
  9. Replace the transparent cap on the tip of the pump after cleaning the tip with a clean cloth or an alcohol swab.

Other uses for this medicine

Ask your doctor or pharmacist for more details if you believe this drug should be used for something else.

What special precautions should I follow?

Before using cyanocobalamin nasal gel ,

  • Inform your doctor and pharmacist if you have any allergies to cobalt, cyanocobalamin, hydroxycobalamin, multivitamins, or any other drugs or vitamins.
  • Inform your physician and pharmacist about all prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products you are taking. Incorporate any of the following: azathioprine, antibiotics like chloramphenicol, chemotherapy for cancer, colchicine, folic acid, and iron supplements, as well as lamivudine (Epivir) and zidovudine (Retrovir), two drugs for the human immunodeficiency virus (HIV) or acquired immunodeficiency syndrome (AIDS), methotrexate (Rheumatrex, Trexall), para-aminosalicylic acid (P (Daraprim). Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects.
  • Inform your doctor if you consume large amounts of alcohol or have ever done so, have any type of infection, have Leber’s hereditary optic neuropathy (slow, painless loss of vision, first in one eye then in the other), have allergies that frequently cause your nose to be stuffed, itchy, or runny, or if you have kidney disease.
  • If you experience a cold, runny, or stuffy nose at any point while undergoing treatment, let your doctor know. Until your symptoms go away, you might need to take vitamin B12 in a different form.
  • Inform your doctor if you are expecting, intend to get pregnant, or are nursing a baby. Call your doctor if you become pregnant while using cyanocobalamin nasal gel. When you are pregnant or nursing, discuss with your doctor how much vitamin B12 you need to consume daily.

What special dietary instructions should I follow?

Keep eating normally unless your doctor instructs you otherwise.

What should I do if I forget a dose?

The missed dose should be taken as soon as you remember. If the next dose is soon due, skip the missed one and carry on with your regular dosing plan. To make up for a missing dose, do not take a second one.

What side effects can this medication cause?

Side effects from cyanocobalamin nasal gel are possible. If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Headache
  • Uneasy stomach
  • Runny or clogged nose
  • Aching tongue
  • Weakness

Some adverse effects can be very harmful. Even though the following signs are unusual, you should call your doctor right once if you notice any of them:

  • Significant bruising or bleeding
  • Weakened, cramped, or painful muscle
  • Leg ache
  • Severe thirst
  • Excessive urination
  • Confusion
  • Tingling or burning in the hands, feet, legs, or arms
  • Fever, chills, or other symptoms of illness in addition to a sore throat
  • Rash
  • Hives
  • Itching
  • Breathing or swallowing challenges

Other adverse effects of Cyanocobalamin nasal gel include rash, hives, itching, and trouble breathing or swallowing. If you experience any strange issues while taking this medicine, contact your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep this medication out of the reach of children and upright in the carton it came in with the lid properly closed. Store it away from excessive heat and moisture at room temperature (not in the bathroom). Keep the drug from freezing.

Unused prescriptions must be disposed of carefully to prevent pets, kids, and other people from ingesting them. You should not, however, dispose of this medication in the toilet. Instead, utilising a medicine take-back programme is the easiest approach to get rid of your medication. To find out about take-back programmes in your area, speak with your pharmacist or the garbage/recycling department in your city. If you do not have access to a take-back programme, see the FDA’s Safe Disposal of Medicines website at for additional information.

As many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Always lock safety caps and promptly stash medication up and away from young children where it is out of their sight and reach to prevent poisoning.

In case of emergency/overdose

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Additionally, information can be found online at Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

What other information should I know?

Keep all of your appointments with your physician and the lab. To determine how well your body is responding to cyanocobalamin nasal gel, your doctor will request a few lab tests.

No one else should take your medication. Any queries you may have regarding medication refills should be directed to your pharmacist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • Nascobal®
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