In persons who have heart disease or who are at risk of developing heart disease, rosuvastatin is used in conjunction with diet, weight loss, and exercise to lower the risk of heart attack and stroke and to lower the likelihood that heart surgery will be required. In addition, rosuvastatin is used to raise levels of high-density lipoprotein (HDL) cholesterol, commonly known as “good cholesterol,” and to lower levels of triglycerides and low-density lipoprotein cholesterol, generally known as “bad cholesterol” in the blood. Children and teens with familial heterozygous hypercholesterolemia 8 to 17 years old may also take rosuvastatin together with a diet to lower their blood cholesterol and other fatty substance levels (an inherited condition in which cholesterol cannot be removed from the body normally). Rosuvastatin is used to lower blood levels of cholesterol and other fatty substances in adults, children, and teenagers 7 to 17 years old with familial homozygous hypercholesterolemia, either alone or in conjunction with other drugs (an inherited condition in which cholesterol cannot be removed from the body normally). A class of drugs known as HMG-CoA reductase inhibitors includes rosuvastatin (statins). It functions by reducing the amount of cholesterol that may accumulate on the artery walls and obstruct blood flow to the heart, brain, and other organs of the body. This is done by delaying the body’s creation of cholesterol.

Your heart, brain, and other organs of your body receive less oxygen as a result of the buildup of cholesterol and fats along the artery walls (a condition known as atherosclerosis). It has been demonstrated that rosuvastatin can prevent heart disease, angina (chest discomfort), strokes, and heart attacks by lowering your blood’s cholesterol and fat levels.

Rosuvastatin is available as a tablet to swallow called Crestor. Additionally, rosuvastatin is available as a pill (Ezallor) that can be opened, mixed with water, and administered through a feeding tube. Typically, it is taken once day, with or without food. Take rosuvastatin every day at roughly the same time. Ask your doctor or pharmacist to explain any instructions on your prescription label that you are unsure about following. Rosuvastatin should be taken as prescribed. Never take it in larger or less amounts or more frequently than directed by your doctor.

Most likely, your doctor will start you on a modest dose of rosuvastatin and gradually raise it, not more than once every two to four weeks.

Do not chew or shatter the capsules (Ezallor); instead, swallow them whole. If you are unable to swallow the capsule, carefully open it and sprinkle the contents over a teaspoon of applesauce. Without chewing, instantly swallow the entire concoction. The applesauce combination shouldn’t be kept for later use.

Rosuvastatin should still be taken even if you feel fine. Without consulting your doctor, do not discontinue taking rosuvastatin.

Ask your doctor or pharmacist for more details if you believe this drug should be used for something else.

Before taking rosuvastatin,

• If you have any allergies, including to any of the substances in rosuvastatin tablets or capsules, notify your doctor and pharmacist very away. Request a list of the components from your pharmacist.
• Inform your doctor and pharmacist about any vitamins, nutritional supplements, herbal items, and prescription and over-the-counter medicines you are now taking or intend to take. Any of the following should be mentioned: anticoagulants (also known as “blood thinners”) like cyclosporine (Gengraf, Neoral, and Sandimmune); warfarin (Coumadin, Jantoven); colchicine (Colcrys); cimetidine (Tagamet); darolutamide (Nubeqa), eltrombopag (Promacta), ketoconazole (Nizoral), as well as other drugs for high cholesterol such fenofibrate (Tricor), gemfibrozil (Lopid), and niacin (Niaspan, Niacor); specific drugs for hepatitis C virus (HCV), such as dasabuvir used with ombitasvir, paritaprevir, and ritonavir (Viekira Pak); glecaprevir in combination with pibrentasvir (Mavyret), ledipasvir in combination with sofosbuvir (Harvoni), simeprevir (no longer available in the US), or sofosbuvir in combination with velpatasvir and/or voxilaprevir (Epclusa, Vosevi); certain HIV protease inhibitors, such as atazanavir (Reyataz) in combination (Aldactone). Tell your doctor about every medicine you are taking, even those not on this list, as many other drugs may also interact with rosuvastatin. The dosage of your drugs may need to be adjusted, and your health may need to be closely watched for any negative effects.
• Take antacids containing aluminium and magnesium hydroxide, such as Mylanta and Maalox, at least two hours after taking rosuvastatin.
• In case you have liver problems, let your doctor know. Even if you do not believe you have liver disease, your doctor will still conduct tests to see how well your liver is functioning. If you have liver disease or if the results of the tests indicate that you might be developing liver disease, your doctor will likely advise you not to take rosuvastatin.
• Inform your doctor if you are Asian, use more than two alcoholic beverages per day, are 65 years of age or older, have ever had liver illness, experience seizures, weakness or muscle aches, low blood pressure, kidney or thyroid disease, or if any of the following apply to you:
• If you are pregnant or plan to become pregnant, let your doctor know. Pregnancy should not occur when taking rosuvastatin. Consult your physician about birth control options you can take while undergoing therapy. Rosuvastatin can cause pregnancy, so call your doctor right once if it does. The foetus could be harmed by rosuvastatin.
  while taking rosuvastatin, refrain from breastfeeding.
• Inform your doctor or dentist that you are taking rosuvastatin if you are having surgery, including dental surgery.
• Inform the medical professional caring for you that you are taking rosuvastatin if you are admitted to the hospital due to a major injury or infection.
• Inquire with your doctor if drinking alcohol is okay for you to do while taking rosuvastatin. Drinking alcohol can make major side effects more likely.

Consume a diet low in fat and cholesterol. Make sure to abide by all dietary and exercise advice given to you by your physician or nutritionist. For more dietary advice, you can also refer to the National Cholesterol Education Program (NCEP) website.

If you miss a dosage, take it as soon as you recall. Nevertheless, omit the missed dose and go on with your regular dosing schedule if there are less than 12 hours until your next dose is scheduled. To make up for a missing dose, do not take a second one.

Rosuvastatin might have negative effects. If any of these symptoms are severe or do not go away, let your doctor know right once:

• Constipation
• Abdominal pain
• Dizziness
• Having trouble falling or staying asleep
• Depression
• Joints hurt
• Headache
• Forgetfulness or memory loss
• Confusion

Some adverse effects can be very harmful. Get emergency medical assistance or call your doctor right away if you develop any of the following symptoms:

• Muscle pain, tenderness, or weakness
• Enough energy
• Fever
• Chest ache
• Fatigue, muscle aches, a drop in urine volume, and dark, crimson pee
• Eyes or skin that have a yellow tint
• Urine with a dark colour
• Abdomen’s upper right corner is hurting.
• Nausea
• Extreme fatigue
• Weakness
• Uncommon bruising or bleeding
• Reduced appetite
• Flu-like signs
• Rash
• Hives
• Itching
• Breathing or swallowing challenges
• Edoema of the hands, feet, ankles, lower legs, cheeks, neck, tongue, lips, and eyes
• Hoarseness

Other negative effects of rosuvastatin are possible. If you experience any strange issues while taking this medicine, contact your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

Keep this medication tightly closed in the original container and out of the reach of children. Store it away from excessive heat and moisture at room temperature (not in the bathroom).

As many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Always lock safety caps and promptly stash medication up and away from young children where it is out of their sight and reach to prevent poisoning. http://www.upandaway.org

Unused prescriptions must be disposed of carefully to prevent pets, kids, and other people from ingesting them. You should not, however, dispose of this medication in the toilet. Instead, utilising a medicine take-back programme is the easiest approach to get rid of your medication. To find out about take-back programmes in your area, speak with your pharmacist or the garbage/recycling department in your city. If you do not have access to a take-back programme, see the FDA’s Safe Disposal of Medicines website at http://goo.gl/c4Rm4p for additional information.

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Additionally, information can be found online at https://www.poisonhelp.org/help. Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

Keep all of your appointments with your physician and the lab. During your therapy, your doctor could request lab testing, particularly if you start to have symptoms of liver damage.

Inform the lab staff and your doctor that you are taking rosuvastatin prior to any laboratory test.

No one else should take your medication. Any queries you may have regarding medication refills should be directed to your pharmacist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.