Duvelisib may result in serious or fatal infections. If you develop an infection or have ever had cytomegalovirus, let your doctor know (CMV; a viral infection that may cause symptoms in patients with weak immune systems). Call your doctor right away if you suffer any of the following symptoms: fever, sore throat, chills, shortness of breath, or any indications of infection.

Duvelisib may result in colitis or diarrhoea (swelling of the large intestine). If you experience diarrhoea, have previously had colitis, or have any other disorders that damage your stomach or intestines, let your doctor know. Call your doctor right away if you have any of the following symptoms: an increase in daily bowel movements, blood in your stool, or any other of the following

Duvelisib may result in serious or fatal infections. If you develop an infection or have ever had cytomegalovirus, let your doctor know (CMV; a viral infection that may cause symptoms in patients with weak immune systems). Call your doctor right away if you suffer any of the following symptoms: fever, sore throat, chills, shortness of breath, or any indications of infection.

Duvelisib may result in pneumonitis that is severe or fatal (swelling of the lungs). If you have lung illness or breathing issues, let your doctor know. Call your doctor right away if you have any of the following symptoms: respiratory problems, wheezing, or breathlessness, either new or worsening.

Keep all of your appointments with your physician and the lab. To monitor your body’s reaction to duvelisib, your doctor will prescribe a number of tests.

If you need a prescription refill for duvelisib, your doctor or pharmacist will provide you the manufacturer’s patient information leaflet (Medication Guide). If you have any questions, carefully read the material and contact your doctor or pharmacist. The Medication Guide is also available on the manufacturer’s website or the Food and Drug Administration (FDA) website (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm).

Small lymphocytic lymphoma (SLL), a kind of cancer that primarily starts in the lymph nodes, and chronic lymphocytic leukaemia (CLL), both of which have returned or are not responding to at least two earlier treatments, are both treated with duvelisib. The drug duvelisib belongs to the group of drugs known as kinase inhibitors. It functions by suppressing the impulses that lead to the growth of cancer cells. This aids in halting the growth of cancer cells.

Duvelisib is available as a pill to swallow. Most people take it twice a day, with or without food. Take duvelisib every day at roughly the same time. Ask your doctor or pharmacist to explain any instructions on your prescription label that you are unsure about following. Use duvelisib precisely as advised. Never take it in larger or less amounts or more frequently than directed by your doctor.

Do not chew, break, or open the capsules; instead, swallow them whole.

If you suffer severe adverse effects while receiving therapy, your doctor may reduce your duvelisib dosage or advise you to stop taking the medicine temporarily or permanently. The effectiveness of the drug and any negative side effects you encounter will determine this. Discuss your feelings regarding your treatment with your doctor. Duvelisib should still be used even if you feel OK. Without first consulting your doctor, do not discontinue taking duvelisib.

Ask your doctor or pharmacist for more details if you believe this drug should be used for something else.

Before taking duvelisib,

• If you have any allergies, including to duvelisib, other drugs, or any of the substances in duvelisib capsules, notify your doctor right away. For a list of the ingredients, consult the Medication Guide or speak with your pharmacist.
• While using duvelisib, be sure to let your doctor and pharmacist know what prescription and over-the-counter drugs, vitamins, herbal items, and nutritional supplements you are currently taking or intend to use. Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects.
• Duvelisib may interact with the nonprescription or natural products listed below: Weed of Saint. John. When beginning to take duvelisib, be sure to let your doctor and pharmacist know that you are taking these medications. While taking duvelisib, avoid starting any of these medications without first consulting your doctor.
• If you have liver illness now or previously, let your doctor know.
• If you are pregnant or plan to become pregnant, let your doctor know. A pregnancy test is required before beginning to use duvelisib. Pregnancy should not occur while you are receiving duvelisib therapy. Use birth control to avoid getting pregnant while receiving duvelisib medication and for at least a month after your last dosage if you are a female. Use reliable birth control during treatment and for a month following your last dose if you’re a man and your spouse is capable of getting pregnant. Call your doctor right away if you or your partner become pregnant while taking duvelisib. The foetus may suffer from duvelisib.
• If you are breastfeeding, let your doctor know. If you are using duvelisib, you should stop breastfeeding for at least a month following your last dosage.

Keep eating normally unless your doctor instructs you otherwise.

Take the missed dose of duvelisib as soon as you remember it if you miss it by less than six hours, and then take the subsequent dose at the regular time. In contrast, skip the missed dose and carry on with your regular dosing plan if you miss it by more than 6 hours. To make up for a missing dose, do not take a second one.

Duvelisib might have negative effects. If any of these symptoms are severe or do not go away, let your doctor know right once:

• Nausea
• Vomiting
• Constipation
• Tiredness
• Headache
• Muscle or joint pain

Certain adverse effects can be very harmful. Call your doctor right away or seek emergency medical attention if you develop any of these signs or any of the ones detailed in the IMPORTANT CAUTION section:

• Yellow eyes or skin, pain in the upper right region of the stomach, bruising or bleeding that isn’t explained, loss of appetite, yellow or brown urine, pale faces, or yellow or brown urine.

Further adverse effects of duvelisib are possible. If you experience any strange issues while taking this medicine, contact your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

Keep this medication out of the reach of children and tightly closed in the original container. Keep it at normal temperature, away from sources of extreme heat and moisture (not in the bathroom).

All medications should be kept out of the sight and reach of children, as many of the containers (such as weekly pill containers and those for eye drops, lotions, patches, and inhalers) are not child-resistant and are simple for small children to open. Always lock safety caps and put the medication in a secure spot right away, up high and out of young children’s sight and reach, to prevent poisoning. http://www.upandaway.org

Unused prescriptions must be disposed of carefully to prevent pets, kids, and other people from ingesting them. You should not, however, dispose of this medication in the toilet. Instead, utilising a medicine take-back programme is the easiest approach to get rid of your medication. To find out about take-back programmes in your area, speak with your pharmacist or the garbage/recycling department in your city. If you do not have access to a take-back programme, see the FDA’s Safe Disposal of Medications website at http://goo.gl/c4Rm4p for additional information.

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Moreover, information can be found online at https://www.poisonhelp.org/help. Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

No one else should take your medication. Any queries you may have regarding medication refills should be directed to your pharmacist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.