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Cobavite (Generic Cyanocobalamin Injection)

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Why is this medication prescribed?

A lack of vitamin B12 may be brought on by any of the following: pernicious anaemia (lack of a natural substance required to absorb vitamin B12 from the intestine); specific illnesses, infections, or medications that reduce the amount of vitamin B12 absorbed from food; or a vegan diet. Cyanocobalamin injection is used to treat and prevent such vitamin B12 deficiencies (strict vegetarian diet that does not allow any animal products, including dairy products and eggs). A deficiency in vitamin B12 can result in lasting nerve damage and anaemia, a condition in which the red blood cells are unable to carry enough oxygen to the organs. Injections of cyanocobalamin may also be administered as a test to determine how well the body can assimilate vitamin B12. Injections of cyanocobalamin belong to the category of drugs known as vitamins. It can be used to provide vitamin B12 to patients who cannot absorb this vitamin through the intestine because it is injected directly into the bloodstream.

How should this medicine be used?

The liquid form of cyanocobalamin is available for injection into a muscle or just below the skin. In an office or clinic, a medical professional often administers the injection. Throughout the first 6-7 days of your treatment, cyanocobalamin injections will likely be given to you once daily. You will likely take the drug every other day for two weeks, then every three to four days for two to three and a half weeks, while your red blood cells begin to function normally. You will likely take the drug once a month once your anaemia has been treated to keep your symptoms from returning.

You can only get enough vitamin B12 from a cyanocobalamin injection if you get them frequently. For the rest of your life, you might get injections of cyanocobalamin every month. Maintain all appointments for injections of cyanocobalamin, even if you feel fine. Your anaemia could recur and your nerves could get hurt if you stop getting cyanocobalamin injections.

Other uses for this medicine

Injections of cyanocobalamin are also occasionally used to treat hereditary diseases that reduce the absorption of vitamin B12 from the intestine. Injections of cyanocobalamin are also occasionally used to treat methylmalonic aciduria, a condition in which the body is unable to break down protein. They are also occasionally administered to unborn children to avoid methylmalonic aciduria after delivery. The potential dangers of using this medication for your illness should be discussed with your doctor.

Ask your doctor or pharmacist for more details if you think this drug may be recommended for other conditions.

What special precautions should I follow?

Before using cyanocobalamin injection,

  • If you have any allergies, including to cyanocobalamin injection, nasal gel, or tablets; hydroxocobalamin; multivitamins; other drugs or vitamins; or cobalt, let your doctor and pharmacist know right away.
  • Inform your physician and pharmacist about all prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products you are taking. Mention any of the following: para-aminosalicylic acid (Paser), pyrimethamine, methotrexate (Rheumatrex, Trexall), colchicine, folic acid, and antibiotics like chloramphenicol (Daraprim). Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects.
  • Inform your doctor if you regularly consume significant amounts of alcohol, have ever experienced Leber’s hereditary optic neuropathy (slow, painless loss of vision that begins in one eye and progresses to the other), or have ever had renal illness.
  • Inform your doctor if you are expecting, intend to get pregnant, or are nursing a baby. Call your doctor if you become pregnant while receiving cyanocobalamin injections. When you are pregnant or nursing, discuss with your doctor how much vitamin B12 you need to consume daily.

What special dietary instructions should I follow?

Maintain your regular diet unless your doctor instructs you otherwise.

What should I do if I forget a dose?

Call your doctor as soon as you can if you can’t make it to your appointment for a cyanocobalamin injection.

What side effects can this medication cause?

Side effects from cynocobalamin injection are possible. If any of these symptoms are severe or do not go away, consult your doctor right once:

  • Diarrhea
  • Feeling like your body is completely enlarged

Some adverse effects may be severe. Although the following signs are unusual, if you notice any of them, consult your doctor right away:

  • Weakened, cramped, or painful muscle
  • Leg ache
  • Severe thirst
  • Excessive urination
  • Confusion
  • Breathing problems, especially while lying down or exercising
  • Wheeze or coughing
  • Rapid heart rate
  • Extreme fatigue
  • Arms, hands, foot, ankles, or lower legs swelling
  • One leg: warmth, redness, swelling, or tenderness
  • Headache
  • Dizziness
  • Skin tone that is red, especially on the face
  • Hives
  • Rash
  • Itching
  • Breathing or ingesting

Further negative effects from cyanocobalamin injection are possible. If you experience any strange issues while taking this medicine, contact your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

What should I know about storage and disposal of this medication?

This medication will be kept by your doctor at their office.

In case of emergency/overdose

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Moreover, information can be found online at Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

What other information should I know?

Keep all of your appointments with your physician and the lab. To determine how well your body has responded to the cyanocobalamin injection, your doctor will request a few lab tests.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • Berubigen®
  • Betalin 12®
  • Cobavite®
  • Redisol®
  • Rubivite®
  • Ruvite®
  • Vi-twel®
  • Vibisone®
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