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Clorpres (Generic Chlorthalidone)

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Why is this medication prescribed?

Chlorthalidone, also known as a “water pill,” is used to treat fluid retention and high blood pressure brought on by a variety of illnesses, including heart disease. It makes the kidneys flush out salt and water from the body through the urine.

Ask your doctor or pharmacist for more details if you’re interested in using this drug for any other conditions.

How should this medicine be used?

Chlorthalidone is available as an oral tablet. It is often taken after a meal, especially breakfast, once daily or every other day. To minimise having to use the restroom at night, it is preferable to take this medication in the morning. Ask your doctor or pharmacist to explain any instructions on your prescription label that you are unsure about following. Follow the medication’s directions precisely. Never take it in larger or less amounts or more frequently than directed by your doctor.

Chlorthalidone manages hypertension but does not treat it. Chlorthalidone should still be used even if you feel fine. Without consulting your doctor, do not stop taking chlorthalidone.

Other uses for this medicine

Chlorthalidone may also be used to avoid kidney stones in patients with excessive blood calcium levels, treat patients with diabetes insipidus, treat some electrolyte imbalances, and treat people with diabetes insipidus. Discuss the potential dangers of using this medicine for your illness with your doctor.

What special precautions should I follow?

Before taking chlorthalidone,

  • If you have an allergy to chlorthalidone, sulfa medications, or any other medications, tell your doctor and pharmacist.
  • Inform your doctor and pharmacist about all prescription and over-the-counter medications you are taking, especially any other high blood pressure medications, aspirin, ibuprofen, naproxen, lithium (Eskalith, Lithobid), corticosteroids (e.g., prednisone), diabetes medications, probenecid (Benemid), and vitamins. Take cholestyramine or colestipol at least one hour after taking chlorthalidone if you are also taking these medications.
  • Inform your doctor if you currently have or previously had renal, liver, thyroid, parathyroid, or diabetes.
  • Inform your doctor if you are expecting, intend to get pregnant, or are nursing a baby. Call your doctor right away if you get pregnant while taking chlorthalidone.
  • You should let your doctor or dentist know that you are taking chlorthalidone if you are having surgery, including dental surgery.
  • You should be aware that this medication might make you sleepy. Until you are certain of how this medication affects you, do not operate machinery or drive a car.
  • Keep in mind that drinking can exacerbate the effects of this drug’s sedation.
  • Have a plan to limit your time spent in the sun and to use sunscreen, sunglasses, and protective clothes. Your skin could become sun-sensitive if you use chlorthalidone.

What special dietary instructions should I follow?

Observe your doctor’s recommendations. A daily exercise routine, a low-sodium or low-salt diet, potassium supplements, and consuming more potassium-rich foods (such as bananas, prunes, raisins, and orange juice) are a few examples.

What should I do if I forget a dose?

If you miss a dosage, take it as soon as you recall. If your next dose is approaching, skip the missed one and carry on with your regular dosing regimen. To make up for a missing dose, do not take a second one.

What side effects can this medication cause?

You should experience less frequent urination after taking chlorthalidone for a few weeks.

If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Muscular tremor
  • Dizziness
  • Cramps
  • Thirst
  • Abdominal pain
  • Uneasy stomach
  • Vomiting
  • Diarrhea
  • Reduced appetite
  • Headache
  • Hair fall

Call your doctor right away if you have any of the following symptoms:

  • Throat infection with fever
  • Uncommon bruising or bleeding
  • Severe skin rash with skin that is peeling
  • Breathing or swallowing challenges

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep this medication tightly closed in the original container and out of the reach of children. Keep it away from excessive heat and moisture at room temperature (not in the bathroom).

Unused prescriptions must be disposed of carefully to prevent pets, kids, and other people from ingesting them. You should not, however, dispose of this medication in the toilet. Instead, utilising a medicine take-back programme is the easiest approach to get rid of your medication. To find out about take-back programmes in your area, speak with your pharmacist or the garbage/recycling department in your city. If you do not have access to a take-back programme, see the FDA’s Safe Disposal of Medications website at for additional information.

Although many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Always lock safety caps and promptly stash medication up and away from young children where it is out of their sight and reach to prevent poisoning.

In case of emergency/overdose

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Moreover, information can be found online at Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

What other information should I know?

Keep all of your appointments with your physician and the lab. Blood tests should be performed occasionally, and your blood pressure should be checked often.

No one else should take your medication. Any queries you may have regarding medication refills should be directed to your pharmacist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • Hygroton®
  • Thalitone®
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