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Cisapride

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WARNING

Only selected patients who have been authorised by their doctors can obtain cisapride in the United States. If you’re unsure if you should be taking cisapride, consult your doctor or pharmacist.

Cisapride may result in fatally dangerous irregular heartbeats. If you have or have ever had irregular heartbeats, heart disease, severe dehydration, vomiting, eating disorders, kidney failure, or lung failure, let your doctor know.

Inform your doctor of all prescription and over-the-counter medications you are using. Cisapride should not be taken if you are also taking bepridil (Vascor), chlorpromazine (Thorazine), clarithromycin (Biaxin), erythromycin (E.E.S., E-Mycin, Ery-Tab), fluconazole (Diflucan), fluphenazine (Prolixin), itraconazole (Sporanox), ketoconazole (Nizoral), fluphenazine (Prolixin); drugs for depression, such as amitriptyline (Elavil), amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Adapin, Sinequan), imipramine (Tofranil), maprotiline (Ludiomil), nefazodone (Serzone), nortriptyline (Pamelor), protriptyline (Vivactil); mesoridazine (Serentil), perphenazine (Trilafon), prochlorperazine (Compazine), amiodarone (Cordarone), disopyramide (Norpace), quinidine (Quinidex), procainamide (Procanbid, Pronestyl), and sotalol (Betapace) are drugs for irregular heartbeats. Sertindole (Serlect), sparfloxacin (Zagam), thioridazine (Mellaril), thiothixene (Navane), trifluoperazine (Stelazine), or troleandomycin are protease inhibitors. Promethazine (Phenergan) is another example (Tao). When taking cisapride, avoid drinking grapefruit juice.

Never take cisapride in larger or more frequent doses than recommended by your doctor. Keep all of your appointments with your physician and the lab. To monitor your body’s reaction to cisapride, your doctor will request specific lab tests.

Call your doctor right away if you have any of the following symptoms: dizziness or rapid or irregular heartbeats.

Why is this medication prescribed?

Cisapride is used to treat nocturnal heartburn symptoms in patients who have not improved with previous medications.

How should this medicine be used?

Cisapride is available as a liquid and tablet for oral consumption. Cisapride is often given four times a day, once before sleep and twice 15 minutes before meals. Ask your doctor or pharmacist to explain any instructions on your prescription label that you are unsure about following. Consume cisapride as prescribed. Never take it in larger or less amounts or more frequently than directed by your doctor.

Other uses for this medicine

Ask your doctor or pharmacist for more details if you want to use this drug for something else.

What special precautions should I follow?

Before taking cisapride,

  • If you have any medicine or cisapride allergies, notify your doctor and pharmacist right away.
  • Tell your doctor and pharmacist what prescription and nonprescription medications, notably anticholinergics (atropine, belladonna, benztropine, dicyclomine, etc.), antianxiety medications, and other medications you are taking in addition to those specified in the IMPORTANT WARNING section. Diuretics (also known as “water pills”), miconazole (Monistat), warfarin (Coumadin), azithromycin (Zithromax), cimetidine (Tagamet), and scopolamine are examples of anticoagulants (also known as “blood thinners”). Vitamins and tranquillizers are also included in this list.
  • If you have digestive issues or bleeding ulcers, let your doctor know.
  • Inform your doctor if you are expecting, intend to get pregnant, or are nursing a baby. Call your doctor if you become pregnant while taking cisapride.
  • You should be aware that this medication might make you sleepy. Until you are certain of how this medication affects you, do not operate machinery or drive a car.
  • Keep in mind that drinking can exacerbate the effects of this drug’s sedation.

What should I do if I forget a dose?

If you miss a dosage, take it as soon as you recall. If the next dose is soon due, skip the missed one and carry on with your regular dosing plan. To make up for a missing dose, do not take a second one.

What side effects can this medication cause?

Cisapride could have negative effects. If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Diarrhoea
  • Uneasy stomach
  • Digestive discomfort
  • Headache
  • Blocked nose
  • Constipation
  • Coughing

Call your doctor right away if you have any of the following symptoms or any of those in the IMPORTANT WARNING section:

  • Vision alterations
  • Chest pain

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep this medication tightly closed in the original container and out of the reach of children. Keep it away from excessive heat and moisture at room temperature (not in the bathroom).

Although many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Always lock safety caps and promptly stash medication up and away from young children where it is out of their sight and reach to prevent poisoning. http://www.upandaway.org

Unused prescriptions must be disposed of carefully to prevent pets, kids, and other people from ingesting them. You should not, however, dispose of this medication in the toilet. Instead, utilising a medicine take-back programme is the easiest approach to get rid of your medication. To find out about take-back programmes in your area, speak with your pharmacist or the garbage/recycling department in your city. If you do not have access to a take-back programme, see the FDA’s Safe Disposal of Medications website at http://goo.gl/c4Rm4p for additional information.

In case of emergency/overdose

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Information is also available online at https://www.poisonhelp.org/help. Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

What other information should I know?

Keep all of your appointments with your physician and the lab. To monitor how you are responding to cisapride, your doctor will request a few lab tests.

Do not let anyone else take your medicine. Any queries you may have regarding medication refills should be directed to your pharmacist.

It is vital for you to keep a documented list of all of the prescription and nonprescription (over-the-counter) drugs you are taking, as well as any items such as vitamins, minerals, or other dietary supplements. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • Propulsid®
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