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Patients with congestive heart failure had a higher chance of dying from drugs identical to cilostazol (condition in which the heart is unable to pump enough blood to the other parts of the body). If you have congestive heart failure now or ever had it, let your doctor know. Most likely, your doctor will advise against taking cilostazol.

The dangers of using cilostazol should be discussed with your doctor.

Why is this medication prescribed?

While treating intermittent claudication, clostazol is used (pain in the legs that worsens when walking and improves when resting that is caused by narrowing of the blood vessels that supply blood to the legs). Plaquelet-aggregation inhibitors, which include clostazol, are a class of drugs (antiplatelet medications). It enhances blood flow to the legs, which is how it works.

How should this medicine be used?

Cilostazol is available as an oral tablet. It is often taken twice day, at least two hours prior to or following breakfast and dinner. Cilostazol should be taken every day at roughly the same time. Ask your doctor or pharmacist to explain any instructions on the prescription label that you do not understand, and carefully follow their instructions. Follow the prescription for cilostazol strictly. Never take it in larger or less amounts or more frequently than directed by your doctor.

Intermittent claudication cannot be cured, however clostazol can manage the symptoms. Even while you may start to feel better in two to four weeks, it could take up to 12 weeks before you start to experience the full benefits of cilostazol (increased walking distance). Regardless of how you feel, keep taking cilostazol. Cilostazol shouldn’t be stopped without first consulting your doctor.

Other uses for this medicine

Ask your doctor or pharmacist for more details if you’re interested in using this drug for any other conditions.

What special precautions should I follow?

Before taking cilostazol,

  • If you have an allergy to cilostazol, any other drugs, or any of the substances in cilostazol, inform your doctor right away. Get a list of the components from your pharmacist.
  • Inform your doctor and pharmacist about any additional prescription and over-the-counter medications, vitamins, herbal items, nutritional supplements, and any drugs you are now taking or intend to take. Any of the following should be mentioned: Aspirin, clopidogrel (Plavix), diltiazem (Cardizem, Dilacor, Tiazac, among others), erythromycin (E-mycin, Ery-Tab, among others), fluoxetine (Prozac), fluvoxamine (Luvox), nefazadone, and omeprazole (Prilosec) are examples of anticoagulants (‘blood thinners’), which include warfar (Zoloft). Your doctor might need to adjust your medication doses or keep a close eye out for any negative side effects.
  • Inform your physician if you experience significant bleeding due to bleeding ulcers (sores in the lining of the stomach or small intestine that are bleeding), bleeding in the brain, bleeding from any other area of your body, low platelet counts, or any other ailment. Most likely, your doctor will advise against taking cilostazol.
  • If you have or have had had heart, renal, or liver disease, let your doctor know.
  • Inform your doctor if you are expecting, intend to get pregnant, or are nursing a baby. Call your doctor if you get pregnant while taking cilostazol.

What should I do if I forget a dose?

If you miss a dosage, take it as soon as you recall. If the next dose is soon due, skip the missed one and carry on with your regular dosing plan. To make up for a missing dose, do not take a second one.

What side effects can this medication cause?

Cilostazol could have negative effects. If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Headache
  • Diarrhea
  • Dizziness
  • Heartburn
  • Nausea
  • Abdominal pain
  • Muscular ache

Certain adverse effects can be very harmful. Call your doctor right away if you have any of the following symptoms:

  • Rapid or erratic heartbeat
  • Uncommon bruising or bleeding
  • Edoema of the lower legs, lower arms, feet, ankles, or hands

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep this medication tightly closed in the original container and out of the reach of children. Keep it away from excessive heat and moisture at room temperature (not in the bathroom).

Unused prescriptions must be disposed of carefully to prevent pets, kids, and other people from ingesting them. You should not, however, dispose of this medication in the toilet. Instead, utilising a medicine take-back programme is the easiest approach to get rid of your medication. To find out about take-back programmes in your area, speak with your pharmacist or the garbage/recycling department in your city. If you do not have access to a take-back programme, see the FDA’s Safe Disposal of Medications website at for additional information.

Although many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Always lock safety caps and promptly stash medication up and away from young children where it is out of their sight and reach to prevent poisoning.

In case of emergency/overdose

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Moreover, information can be found online at Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

Symptoms of overdose may include the following:

  • Terrible headache
  • Dizziness
  • Fainting
  • Diarrhea
  • Rapid or erratic heartbeat

What other information should I know?

Keep all of your doctor’s appointments.

No one else should take your medication. Any queries you may have regarding medication refills should be directed to your pharmacist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • Pletal®
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