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Ciloprost (Generic Iloprost)

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Why is this medication prescribed?

In some cases of pulmonary arterial hypertension, iloprost is utilised as a treatment (PAH; high blood pressure in the vessels carrying blood to the lungs, causing shortness of breath, dizziness, and tiredness). In PAH patients, iloprost may enhance exercise capacity and lessen disease progression. Iloprost belongs to the vasodilators class of drugs. It functions by allowing blood vessels, notably those in the lungs, to relax.

How should this medicine be used?

Iloprost is sold as a mouth-to-lung solution. During the waking hours, it is typically breathed six to nine times daily. Implement iloprost exactly as advised. Never take it in larger or less amounts or more frequently than directed by your doctor.

You will be shown how to utilise your delivery device and iloprost inhalation solution by your doctor or nurse. Iloprost preparation and administration instructions must be carefully studied before use. If you have any concerns regarding how to prepare or inhale this drug, be sure to see your doctor, nurse, or pharmacist. Discard any residual medication solution in the delivery device after each dose, and then carefully adhere to the manufacturer’s cleaning recommendations for the delivery system’s components. Iloprost solution shouldn’t be taken with any other drugs.

Iloprost solution should not be ingested. Iloprost solution should never be applied to the skin or eyes without first rinsing them with water. Iloprost inhalers should not be used too close to other people, especially babies and expectant women, to prevent them from inhaling the medicine.

Iloprost inhalers should only be used once every two hours. You might need to change the schedule of your dosages to cover your planned activities because the medication’s effects might not continue for two hours.

Using specific inhaler devices, iloprost solution is used. If your delivery gadget malfunctions for whatever reason, be sure you can quickly obtain a replacement.

Retail pharmacies do not sell iloprost. You will receive your medication via mail from a speciality pharmacy. If you have any concerns about receiving your medication, speak with your doctor.

Although not curing PAH, iloprost manages it. Iloprost should still be taken even if you feel fine. Without consulting your doctor, do not discontinue taking iloprost.

For a copy of the manufacturer’s information for the patient and the user’s manual for the inhaler device, ask your pharmacist or doctor.

Other uses for this medicine

Ask your doctor or pharmacist for more details if you believe this drug should be used for something else.

What special precautions should I follow?

Before taking iloprost,

  • If you have an allergy to iloprost, any other drugs, or any of the substances in iloprost solution, inform your doctor and pharmacist right away. For a list of the ingredients, consult your pharmacist or the manufacturer’s patient information.
  • Inform your doctor and pharmacist about any additional prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products you are now taking or intend to use. Incorporate any of the following: drugs for high blood pressure or other cardiac issues; and anticoagulants (“blood thinners”) such warfarin (Coumadin).
  • Inform your doctor if you have or have ever had kidney or liver illness, asthma, COPD, low blood pressure, or any other medical conditions. If you have an infection in your lungs, let your doctor know as well.
  • Inform your doctor if you are expecting, intend to get pregnant, or are nursing a baby. Call your doctor if you get pregnant while taking iloprost.
  • Iloprost may produce dizziness, lightheadedness, or fainting, particularly if you stand up too fast after lying down or while exerting yourself physically or exercising. Get out of bed gradually and rest your feet on the floor for a few minutes before standing up to help prevent this issue. Until you are certain of how this medication affects you, avoid operating machinery or tools, including an automobile. If you continue to experience fainting while taking iloprost, let your doctor know.

What special dietary instructions should I follow?

Keep eating normally unless your doctor instructs you otherwise.

What should I do if I forget a dose?

If you miss a dosage, take it as soon as you recall. If the next dose is soon due, skip the missed one and carry on with your regular dosing plan. To make up for a missing dose, do not take a second one.

What side effects can this medication cause?

Iloprost could have negative effects. If any of these symptoms, or those listed in the SPECIAL PRECAUTIONS section, are severe or do not go away, consult your doctor:

  • Flushing
  • Cough
  • fuzzy vision
  • Nausea
  • Vomiting
  • Headache
  • Jaw muscles are tense, making it difficult to open your mouth.
  • Having trouble falling or staying asleep
  • Tongue ache

Some adverse effects may be severe. Stop taking iloprost and seek emergency medical attention if you encounter any of these signs:

  • Having trouble breathing
  • Breathing that makes a bubbling, wheezing, or gasping noise
  • Spitting up pink, foamy mucus
  • Greyish-blue hue of the lips or skin

Further adverse effects of iloprost are possible. If you experience any strange issues while taking this medicine, contact your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep this medication tightly closed in the original container and out of the reach of children. Keep it away from excessive heat and moisture at room temperature (not in the bathroom).

Unused prescriptions must be disposed of carefully to prevent pets, kids, and other people from ingesting them. You should not, however, dispose of this medication in the toilet. Instead, utilising a medicine take-back programme is the easiest approach to get rid of your medication. To find out about take-back programmes in your area, speak with your pharmacist or the garbage/recycling department in your city. If you do not have access to a take-back programme, see the FDA’s Safe Disposal of Medications website at for additional information.

Although many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Always lock safety caps and promptly stash medication up and away from young children where it is out of their sight and reach to prevent poisoning.

In case of emergency/overdose

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Moreover, information can be found online at Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

Overdose signs could include the following:

  • Fainting
  • Dizziness
  • fuzzy vision
  • Nausea
  • Vomiting
  • Diarrhea
  • Headache
  • Flushing

What other information should I know?

Keep all of your doctor’s appointments.

No one else should take your medication. Any queries you may have regarding medication refills should be directed to your pharmacist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • Ventavis®
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