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Choline Magnesium Trisalicylate

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Why is this medication prescribed?

Choline magnesium trisalicylate is used to treat sore shoulders and arthritis-related pain, tenderness, inflammation, and stiffness. Moreover, it lowers fever and relieves discomfort. Salicylates are a group of nonsteroidal anti-inflammatory drugs (NSAIDs) that include choline magnesium trisalicylate. It functions by halting the body’s production of a chemical responsible for inflammation, fever, and discomfort.

How should this medicine be used?

The oral medication choline magnesium trisalicylate is available as a tablet and a liquid. Typically, it is taken once to three times each day. Take choline magnesium trisalicylate at roughly the same time each day to help you remember to take it. Ask your doctor or pharmacist to explain any instructions on your prescription label that you are unsure about following. Choline magnesium trisalicylate should be taken exactly as prescribed. Never take it in larger or less amounts or more frequently than directed by your doctor.

Other uses for this medicine

Inquire with your doctor or pharmacist for more details if you believe this drug may be prescribed for other purposes.

What special precautions should I follow?

Before taking choline magnesium trisalicylate,

  • Inform your doctor and pharmacist if you have any drug allergies, including those to aspirin, choline magnesium trisalicylate (Arthropan), diflunisal (Dolobid), salicylate (Argesic, Disalcid, Salgesic), and magnesium salicylate (Doan’s, others).
  • Inform your physician and pharmacist about all prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products you are taking. Incorporate any of the following: acetazolamide (Diamox); antacids; blood-thinning medications such warfarin (Coumadin); dichlorphenamide (Daranide); oral diabetic drugs like glyburide (DiaBeta, Glynase, Micronase), tolazamide (Tolinase), and tolbutamide (Orinase); insulin; acetohexamide (Dymelor), chlorpropamide (Diabinese), glimepiride (Amaryl), glipizide (Glucotrol), and chlorpropamide (Diabinese); methazolamide (GlaucTabs, Neptazane), methotrexate (Rheumatrex), oral steroids like dexamethasone (Decadron, Dexone), methylprednisolone (Medrol), and prednisone (Deltasone), as well as gout drugs such probenecid (Benemid) and sulfinpyrazone (Anturane); aspirin, choline salicylate (Arthropan), diflunisal (Dolobid), magnesium salicylate (Doan’s, others), salsalate (Argesic, Disalcid, Salgesic), phenytoin (Dilantin), and valproic acid are further salicylate analgesics (Depakene, Depakote). Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
  • If you have or have previously had stomach issues including ulcers or kidney or liver illness, let your doctor know.
  • You should be aware that due to the risk of Reye Syndrome, a rare but serious disease, children and teenagers with chicken pox or the flu shouldn’t take choline magnesium trisalicylate.
  • Inform your doctor if you are expecting, intend to get pregnant, or are nursing a baby. Call your doctor if you become pregnant while taking choline magnesium trisalicylate.
  • Inform the surgeon or dentist that you are taking choline magnesium trisalicylate if you are having surgery, including dental surgery.
  • When taking choline magnesium trisalicylate, consult your doctor about the safe consumption of alcoholic beverages. Choline magnesium trisalicylate’s adverse effects can be made worse by alcohol.

What special dietary instructions should I follow?

Keep eating normally unless your doctor instructs you otherwise.

What should I do if I forget a dose?

If you miss a dosage, take it as soon as you recall. If the next dose is soon due, skip the missed one and carry on with your regular dosing plan. To make up for a missing dose, do not take a second one.

What side effects can this medication cause?

Side effects from choline magnesium trisalicylate are possible. If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Uneasy stomach
  • Vomiting
  • Heartburn
  • Diarrhea
  • Constipation
  • Abdominal pain
  • Headache
  • Lightheadedness
  • Dizziness
  • Drowsiness
  • Not enough energy

Some adverse effects may be severe. Although the following signs are unusual, if you notice any of them, consult your doctor right away:

  • Hearing ringing
  • Loss of hearing
  • Stool that is dark and tarry
  • Bench with a reddish tint
  • Tainted vomit
  • Vomiting what appears to be coffee grounds

Further negative effects of choline magnesium trisalicylate are possible. If you experience any strange issues while taking this medicine, contact your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep this medication tightly closed in the original container and out of the reach of children. Keep it away from excessive heat and moisture at room temperature (not in the bathroom).

Unused prescriptions must be disposed of carefully to prevent pets, kids, and other people from ingesting them. You should not, however, dispose of this medication in the toilet. Instead, utilising a medicine take-back programme is the easiest approach to get rid of your medication. To find out about take-back programmes in your area, speak with your pharmacist or the garbage/recycling department in your city. If you do not have access to a take-back programme, see the FDA’s Safe Disposal of Medications website at for additional information.

Although many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Always lock safety caps and promptly stash medication up and away from young children where it is out of their sight and reach to prevent poisoning.

In case of emergency/overdose

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Moreover, information can be found online at Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

Overdose symptoms could include:

  • Headache
  • Dizziness
  • Hearing ringing
  • Loss of hearing
  • Confusion
  • Drowsiness
  • Sweating
  • Vomiting
  • Diarrhea
  • Quickly breathing

What other information should I know?

Keep all of your appointments with your physician and the lab. To determine how your body is reacting to choline magnesium trisalicylate, your doctor may request specific lab tests.

Inform the lab staff and your doctor that you are taking choline magnesium trisalicylate prior to any laboratory test.

No one else should take your medication. Any queries you may have regarding medication refills should be directed to your pharmacist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • Trilisate®
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