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Chlordiazachel (Generic Chlordiazepoxide)

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Chlordiazepoxide may increase the risk of serious or life-threatening breathing problems, sedation, or coma if used along with certain medications. Tell your doctor if you are taking or plan to take certain opiate medications for cough such as codeine (in Triacin-C, in Tuzistra XR) or hydrocodone (in Anexsia, in Norco, in Zyfrel) or for pain such as codeine (in Fiorinal), fentanyl (Actiq, Duragesic, Subsys, others), hydromorphone (Dilaudid, Exalgo), meperidine (Demerol), methadone (Dolophine, Methadose), morphine (Astramorph, Duramorph PF, Kadian), oxycodone (in Oxycet, in Percocet, in Roxicet, others), and tramadol (Conzip, Ultram, in Ultracet). Your doctor may need to change the dosages of your medications and will monitor you carefully. If you take chlordiazepoxide with any of these medications and you develop any of the following symptoms, call your doctor immediately or seek emergency medical care immediately: unusual dizziness, lightheadedness, extreme sleepiness, slowed or difficult breathing, or unresponsiveness. Be sure that your caregiver or family members know which symptoms may be serious so they can call the doctor or emergency medical care if you are unable to seek treatment on your own.

Drinking alcohol or using street drugs during your treatment with chlordiazepoxide also increases the risk that you will experience these serious, life-threatening side effects. Do not drink alcohol or use street drugs during your treatment.

Why is this medication prescribed?

Chlordiazepoxide is used to calm agitation brought on by alcohol withdrawal and to reduce anxiety. Chlordiazepoxide belongs to the group of drugs known as benzodiazepines. It functions by reducing the brain’s aberrant electrical activity.

How should this medicine be used?

Chlordiazepoxide is available as an oral tablet and capsule. With or without food, it is often taken once to four times each day. Ask your doctor or pharmacist to explain any instructions on your prescription label that you are unsure about following. Just as prescribed, take chlordiazepoxide.

Other uses for this medicine

Irritable bowel syndrome can also be treated with chlordiazepoxide. Discuss the potential dangers of using this medicine for your illness with your doctor.

You should speak with your doctor or pharmacist for more details if you want to take this drug for a different purpose.

What special precautions should I follow?

Before taking chlordiazepoxide,

  • If you have an allergy to chlordiazepoxide, alprazolam (Xanax), clonazepam (Klonopin), clorazepate (Gen-Xene, Tranxene), or diazepam, tell your doctor right away (Diastat, Valium), estazolam, flurazepam, lorazepam (Ativan), oxazepam, temazepam (Restoril), triazolam (Halcion), or any other drug or component of a pill or capsule. Get a list of the components from your pharmacist.
  • Inform your doctor and pharmacist about any vitamins, nutritional supplements, herbal items, and prescription and over-the-counter medicines you are now taking or intend to take. Any of the following should be mentioned: Antihistamines, cimetidine (Tagamet), digoxin (Lanoxin), disulfiram (Antabuse), fluoxetine (Prozac, Sarafem, Selfemra), isoniazid (Laniazid, in Rifamate, in Rifater), ketoconazole (Nizoral), and levodopa (in Ritary, Sinemet, and Stalevo), among others; medications for anxiety, depression, Parkinson’s disease, asthma, allergies, or seizures; metoprolol (Lopressor, Toprol XL, others); muscle relaxants; oral contraceptives; probenecid (Probalan, in Col-Probenecid); propranolol (Inderal, Innopran); rifampin (Rifadin, Rimactane, in Rifamate, in Rifater); sedatives; sleeping pills; (Depakene). Your doctor might need to adjust your medication doses or keep a close eye out for any negative side effects.
  • If you have or have had had glaucoma, seizures, lung, heart, or liver illness, let your doctor know.
  • Inform your physician if you are nursing a baby, intend to get pregnant, or are already pregnant. Call your doctor right away if you become pregnant while taking chlordiazepoxide.
  • If you are 65 years of age or older, discuss the advantages and disadvantages of taking chlordiazepoxide with your doctor. Chlordiazepoxide should typically not be taken by older adults because it is neither as safe nor as effective as alternative drugs that can be used to treat the same illness.
  • You should let your doctor or dentist know if you are taking chlordiazepoxide if you are having surgery, including dental surgery.
  • You should be aware that this medicine may cause you to feel sleepy. Prior to understanding how this drug affects you, avoid using machinery or driving a car.

What should I do if I forget a dose?

You should skip the missing dose and carry on with your regular dosing regimen if you take multiple doses throughout the day. To make up for a missing dose, do not take a second one.

What side effects can this medication cause?

Side effects from chlordiazepoxide are possible. If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Drowsiness
  • Dizziness
  • Tiredness
  • Weakness
  • Mouth ache
  • Diarrhoea
  • Ineasy stomach
  • Alterations in appetite

If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Agitation or excitement
  • Constipation
  • Having trouble urinating
  • Excessive urination
  • Fuzzy vision
  • Alterations in sex drive or capacity

Some adverse effects may be severe. Get emergency medical assistance or call your doctor right away if you develop any of the following symptoms or any of those noted in the IMPORTANT WARNING section:

  • Shuffled walking
  • Inability to sit still or a continuous, fine tremor
  • Fever
  • Breathing or swallowing challenges
  • Severely itchy skin
  • Eyes or skin that have a yellow tint
  • Unsteady heartbeat

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep this medication tightly closed in the original container and out of the reach of children. Keep it away from excessive heat and moisture at room temperature (not in the bathroom).

Although many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Always lock safety caps and promptly stash medication up and away from young children where it is out of their sight and reach to prevent poisoning.

Unused prescriptions must be disposed of carefully to prevent pets, kids, and other people from ingesting them. You should not, however, dispose of this medication in the toilet. Instead, utilising a medicine take-back programme is the easiest approach to get rid of your medication. To find out about take-back programmes in your area, speak with your pharmacist or the garbage/recycling department in your city. If you do not have access to a take-back programme, see the FDA’s Safe Disposal of Medications website at for additional information.

In case of emergency/overdose

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Moreover, information can be found online at Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

What other information should I know?

Keep all of your doctor’s appointments.

Using the Gravindex pregnancy test can produce erroneous results if chlordiazepoxide is present.

No one else should take your medication. Any queries you may have regarding medication refills should be directed to your pharmacist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • A-poxide®
  • Chlordiazachel®
  • H-Tran®
  • Librelease®
  • Libritabs®
  • Librium®
  • Lygen®
  • Mitran®
  • Poxi®
  • Librax® (as a combination product containing Clidinium, Chlordiazepoxide)
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