Daunorubicin injection must be administered in a hospital or other healthcare institution under the guidance of a physician with training in administering chemotherapy drugs for cancer.

Any time throughout therapy, as well as months to years after it has ended, daunorubicin has the potential to induce serious or life-threatening heart issues. To determine whether your heart is functioning properly enough for you to safely receive daunorubicin, your doctor will prescribe tests both before and throughout your therapy. These procedures could involve an echocardiogram (a test that utilises sound waves to gauge your heart’s blood-pump efficiency) and an electrocardiogram (ECG), which measures the electrical activity of the heart. In the event that tests reveal a decline in your heart’s capacity to pump blood, your doctor might advise against using this drug. If you have or have previously had a form of heart illness or radiation (x-ray) therapy to the chest area, let your doctor know. Inform your doctor and pharmacist if you are now taking or have ever taken certain cancer chemotherapy drugs including mitoxantrone (Novantrone), cyclophosphamide (Cytoxan), doxorubicin (Doxil), epirubicin (Ellence), idarubicin (Idamycin), or trastuzumab (Herceptin). Call your doctor right away if you have any of the following symptoms: breathing difficulties, hand, foot, ankle, or lower leg edoema, or a rapid, erratic, or pounding heartbeat.

Your bone marrow’s ability to produce blood cells may be severely affected by daunorubicin. This could result in specific symptoms and raise your risk of getting a major infection or bleeding. Call your doctor right away if you have any of the following symptoms: Unusual bleeding or bruises; fever, sore throat, persistent cough, and congestion, among other infection-related symptoms.

If you have kidney or liver problems now or in the past, let your doctor know. If you have liver or kidney illness, your doctor might need to change your dosage.

Keep all of your appointments with your physician and the lab. To monitor your body’s reaction to daunorubicin, your doctor will prescribe a number of tests.

To treat a specific form of acute myeloid leukaemia, daunorubicin is combined with other chemotherapy medicines (AML; a type of cancer of the white blood cells). A specific form of acute lymphocytic leukaemia is also treated with dunorubicin in combination with other chemotherapy medicines (ALL; a type of cancer of the white blood cells). The drug daunorubicin belongs to the anthracycline drug class. It functions by reducing or halting the development of cancer cells within your body.

In a hospital setting, a doctor or nurse will administer daunorubicin intravenously (into a vein) together with other chemotherapy drugs. Daunorubicin is available as a liquid solution or as a powder that must be combined with liquid. Daunorubicin is typically injected once daily on specific days during your treatment period when it is used to treat AML. Daunorubicin is typically injected once per week while treating ALL. The sort of drugs you are taking, how well your body reacts to them, and the type of cancer you have will all affect how long your treatment will last.

For a copy of the manufacturer’s information for the patient, ask your pharmacist or doctor.

Inquire with your doctor or pharmacist for more details if you believe this drug may be prescribed for other purposes.

Before receiving daunorubicin injection,

• If you have an allergy to daunorubicin, any other drugs, or any of the ingredients in daunorubicin injection, let your doctor and pharmacist know right away. Get a list of the components from your pharmacist.
• Inform your doctor and pharmacist about any additional prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products you are now taking or intend to use. Azithromycin (Imuran), cyclosporine (Neoral, Sandimmune), methotrexate (Rheumatrex, Trexall), sirolimus (Rapamune), tacrolimus, and any of the following medications should be mentioned (Prograf). Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects. Daunorubicin may also interfere with other drugs, so be sure to let your doctor know about all the ones you’re taking, even if they’re not on this list.
• Inform your doctor of any medical conditions you now have or have ever had.
• Inform your doctor if you are expecting, intend to get pregnant, or are nursing a baby. Pregnancy should not occur while you are getting an injection of daunorubicin. Call your doctor if you conceive while taking daunorubicin. The foetus could suffer from daunorubicin.

Keep eating normally unless your doctor instructs you otherwise.

Side effects from daunorubicin are possible. If any of these symptoms are severe or do not go away, let your doctor know right once:

• Nausea
• Vomiting
• Mouth- and throat-related sores
• Diarrhea
• Abdominal pain
• Hair fall
• Red faeces

Some adverse effects may be severe. Call your doctor right away if you have any of the following symptoms or any of the ones detailed in the IMPORTANT CAUTION section:

• At the injection site, there may be swelling, burning, discomfort, or redness
• Rash
• Hives
• Itching
• Difficulties swallowing or breathing

Daunorubicin may make you more likely to get other malignancies. The dangers of using this drug should be discussed with your doctor.

Further negative effects of daunorubicin are possible. If you experience any strange issues while taking this medicine, contact your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Moreover, information can be found online at https://www.poisonhelp.org/help. Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.