Ceftolozane and tazobactam are used together to treat a variety of illnesses, such as infections of the abdomen and urinary tract (stomach area). Moreover, it is used to treat specific types of pneumonia that patients who are on ventilators or who were hospitalised developed. Ceftolozane is a member of the cephalosporin family of antibiotics. It kills bacteria to work. Tazobactam belongs to the beta-lactamase inhibitor class of drugs. It functions by halting the bacterial oxidation of ceftolozane. The flu, the common cold, or any other viral diseases cannot be treated with antibiotics.

The injection of ceftolozane and tazobactam is available as a powder that must be combined with fluids and administered intravenously (into a vein) over around one hour every eight hours for four to fourteen days. The sort of illness you have and how well you respond to the medication will determine how long your treatment will last. Ceftolozane with tazobactam injection can be administered at home or in a medical facility. Your doctor will demonstrate how to use the medication if you will be taking ceftolozane and tazobactam injection at home. Make sure you comprehend these instructions, and if you have any issues, consult your healthcare professional.

The first few days of your ceftolozane and tazobactam injectable treatment should see an improvement in your condition. Inform your doctor if your symptoms don’t go away or develop worse. Once the ceftolozane and tazobactam injection has been completed, let your doctor know if you continue to experience signs of infection.

Ask your doctor or pharmacist for more details if you believe this drug should be used for something else.

Before receiving ceftolozane and tazobactam injection,

• If you have any of the following allergies: ceftolozane, tazobactam, piperacillin, and tazobactam (Zosyn), cephalosporin antibiotics such cefaclor, cefadroxil, cefazolin (Ancef, Kefzol), cefditoren (Spectracef), cefepime (Maxipime), cefixime (Suprax), cefotaxime (Claforan), cefuroxime (Ceftin, Zinacef), ceftazidime (Fortaz, Tazicef), ceftibuten (Cedax), ceftriaxone (Rocephin), cefuroxime (Ceftin), cephalexin (Keflex), penicillin antibiotics, any other drugs, or any of the components of ceftolozane and tazobactam injection. For a list of the ingredients, ask your pharmacist.
• Inform your doctor and pharmacist about any additional prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products you are now taking or intend to use. Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects.
• If you have renal illness now or ever have, let your doctor know.
• Inform your doctor if you are expecting, intend to get pregnant, or are nursing a baby. Call your doctor if you conceive while having an injection of ceftolozane and tazobactam.

Keep eating normally unless your doctor instructs you otherwise.

Tazobactam injection with ceftolozane may have adverse effects. If any of these symptoms are severe or do not go away, let your doctor know right once:

• Nausea
• Headache
• Constipation
• Vomiting
• Having trouble falling or staying asleep
• Abdominal pain
• Anxiety

Some adverse effects may be severe. Call your doctor right away or seek emergency medical attention if you have any of these symptoms:

• Severe diarrhoea (watery or bloody faeces) that may be accompanied by cramping in the stomach (may occur up to 2 months or more after your treatment)
• Rash
• Itching
• Hives
• Breathing or swallowing challenges
• Fever and other indications of a new or deteriorating infection

Such adverse effects could be brought on by tazobactam injection and ceftolzane. If you have any strange side effects while taking this medicine, contact your doctor right once.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

Keep all of your appointments with your physician and the lab. To monitor your body’s reaction to the ceftolozane and tazobactam injection, your doctor will request a number of lab tests.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.