Important word of caution for elderly people with dementia:

Research have indicated that older persons taking antipsychotics (medications for mental illness) like cariprazine had an increased risk of dying while receiving treatment for dementia, a brain ailment that affects memory, thinking clearly, communicating, and performing daily tasks. Moreover, older people with dementia may be more likely to get a stroke or mini-stroke while receiving treatment.

The Food and Drug Administration (FDA) has not approved capiprazole for the management of behavioural issues in dementia-affected older individuals. If you, a member of your family, or a person you are caring for has dementia and is taking cariprazine, talk to the doctor who recommended it. Visit the FDA website at http://www.fda.gov/Drugs for further details.

Important caution for those experiencing depressive episodes:

In clinical investigations, a tiny proportion of youngsters, teenagers, and young adults (up to 24 years old) who took mood-elevating antidepressants like cariprazine developed suicidal thoughts (thinking about harming or killing oneself or planning or trying to do so). Antidepressants may increase the risk of suicidality in children, adolescents, and young adults who are depressed or suffering from other mental diseases as compared to those who do not take these medications. The risks of not treating a child’s or teen’s depression exist as well, though. The hazards involved and whether your child needs to take an antidepressant can be discussed with your child’s doctor. Children under the age of 18 have not been studied in cariprazine studies.

Even if you are an adult older than 24, you should be aware that taking cariprazine or other antidepressants could cause unanticipated changes in your mental health. Particularly at the start of your treatment and if your dose is changed, you may experience suicidal thoughts. If you encounter any of the following symptoms, you, your family, or your caretaker should contact your doctor straight away: Increased anxiety, agitation, panic attacks, trouble falling or staying asleep, aggressive conduct, irritability, acting without thinking, intense restlessness, and frenetic abnormal excitement are some of the symptoms of new or worsening depression. Make sure your family or carer is aware of any symptoms that could be significant so they can contact the doctor on your behalf if you are unable to call for help.

If you are taking cariprazine, your doctor will want to visit you frequently, especially at the start of your treatment. Make sure to show up for all of your doctor’s appointment times.

As you start your cariprazine treatment, your doctor or pharmacist will give you the patient information sheet (Medication Guide) from the manufacturer. If you have any questions, carefully read the material and contact your doctor or pharmacist. The Medication Guide is also available on the FDA website.

No of your age, before taking an antidepressant, you or your carer should discuss the advantages and disadvantages of treating your disease with an antidepressant or with alternative medications with your doctor. Discuss the advantages and disadvantages of not treating your condition as well. You should be aware that the likelihood that you may commit suicide increases significantly if you suffer from depression or any mental disorder. This risk is increased if you or a family member currently has, or previously had, bipolar illness (a mood condition that causes mood swings between depressed and abnormally excited), mania (a frantic, abnormally excited mood), or has attempted or thought about attempting suicide. Your illness, symptoms, and personal and family medical history should all be discussed with your doctor. The best course of therapy for you will be decided by you and your doctor.

You should discuss the dangers of taking cariprazine with your doctor.

Schizophrenia is treated with ciprofrazine (a mental illness that causes disturbed or unusual thinking, loss of interest in life, and strong or inappropriate emotions). Those with bipolar I disorder who experience depressive episodes are also treated with cariprazine (manic depressive disorder; a disease that causes episodes of mania, episodes of depression and other abnormal moods). Moreover, it is utilised as a short-term treatment for mixed episodes (manic symptoms combined with depressive symptoms) in persons with bipolar I disorder. Adults with major depressive disorder may potentially take ciprofrazine in addition to other drugs to address their depressed symptoms (MDD). Cariprazine belongs to the group of drugs known as atypical antipsychotics. It functions by altering the way that a few organic brain chemicals behave.

Cariprazine is available as a pill to swallow. Typically, it is taken once day, with or without food. Take cariprazine every day at roughly the same time. Ask your doctor or pharmacist to explain any instructions on your prescription label that you are unsure about following. Take cariprazine as prescribed by your doctor. Never take it in larger or less amounts or more frequently than directed by your doctor.

Based on how well the drug works for you and any adverse effects, your doctor will likely start you on a low dose of cariprazine and gradually raise it.

Although it won’t treat your disease, cariprazine may help you manage your symptoms. Before you experience the full benefits of cariprazine, it could take a few weeks or longer. Cariprazine should still be taken even if you feel OK. Without consulting your doctor, do not discontinue taking cariprazine. If you do not feel like you are improving while receiving cariprazine medication, consult your doctor.

Ask your doctor or pharmacist for more details if you believe this drug should be used for something else.

Before taking cariprazine,

• If you have an allergy to cariprazine, any other drugs, or any of the chemicals in cariprazine capsules, inform your doctor right away. Get a list of the components from your pharmacist.
• Inform your doctor and pharmacist about any prescription and over-the-counter drugs, vitamins, and dietary supplements you are currently taking or intend to take. Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects.
• Cariprazine may interact with the nonprescription or natural products listed below: Weed of Saint. John. When beginning to take cariprazine, make sure to inform your doctor and pharmacist that you are taking this medicine. Without first consulting your doctor, do not begin taking this medicine while taking cariprazine.
• Inform your doctor if you, anybody in your family, or anyone else has ever had diabetes or impaired fasting glucose. Moreover, let your doctor know if you have a low white blood cell count or if you’ve ever experienced one as a side effect of a medicine you took. Inform your physician if you suffer from or have ever suffered from epilepsy, a stroke, a ministroke, a heart attack, heart failure, an irregular heartbeat, low or high blood pressure, high levels of cholesterol and other fatty substances in the blood, balance issues, trouble swallowing, or conditions affecting your heart, liver, or kidneys. Moreover, let your physician know if you are now experiencing severe diarrhoea, vomiting, or any other symptoms of dehydration, or if you ever experience these conditions while on therapy.
• Inform your doctor if you are expecting, especially if you are in the last few months of your pregnancy. Also let them know if you plan to get pregnant or if you are nursing a baby. Call your doctor if you become pregnant while taking cariprazine. If taken throughout the final months of pregnancy, capiprazole may have negative effects on babies after birth.
• You should be aware that cariprazine may cause drowsiness and impair your capacity to reason clearly, decide, and act fast. Until you are aware of how cariprazine will effect you, avoid operating machinery or driving a car while undergoing therapy.
• You should be aware that even if you do not currently have diabetes, you could develop hyperglycemia (increases in blood sugar) while taking this drug. Diabetes is more likely to occur in people with schizophrenia than in non-schizophrenics, and taking cariprazine or other comparable drugs may make diabetes more likely. If you experience any of the following symptoms while receiving treatment: intense thirst, frequent urination, intense hunger, blurred vision, or weakness, call your doctor right once. Calling your doctor as soon as you experience any of these symptoms is crucial because elevated blood sugar can result in the deadly disease known as ketoacidosis. If ketoacidosis is not treated right away, it could become life-threatening. Dry mouth, nausea, vomiting, shortness of breath, fruity-smelling breath, and diminished consciousness are all signs of ketoacidosis.
• You should be aware that cariprazine can make you feel weak, lightheaded, and dizzy if you stand up suddenly from a reclining position. When you initially start taking cariprazine, this happens more frequently. Get out of bed gradually, resting your feet on the floor for a few minutes before standing up, to avoid this issue.
• You should be aware that cariprazine may hinder your body’s ability to cool down when it becomes really hot. If you want to engage in strenuous activity or be exposed to high temperatures, let your doctor know. If you have any of the following symptoms, make sure to drink lots of water and contact your doctor: feeling extremely hot, heavily perspiring, not perspiration even though it is hot, dry mouth, excessive thirst, or decreased urination.

Keep eating normally unless your doctor instructs you otherwise.

If you miss a dosage, take it as soon as you recall. If the next dose is soon due, skip the missed one and carry on with your regular dosing plan. To make up for a missing dose, do not take a second one.

Cariprazine could have negative effects. If any of these symptoms are severe or do not go away, let your doctor know right once:

• Extreme fatigue
• Restlessness
• Anxiety
• Agitation
• Having trouble falling or staying asleep
• Feeling lightheaded, unstable, or having difficulties balancing
• Higher appetite
• Gaining weight
• Constipation
• Indigestion
• Nausea
• Increased drooling or salivation
• Fuzzy vision

Some adverse effects may be severe. Call your doctor right away or seek emergency medical attention if you develop any of the signs or symptoms detailed in the sections titled “IMPORTANT WARNING” or “SPECIAL PRECAUTIONS”:

• Seizures
• Unusual, uncontrollable movements of your face or body
• Slow motion or a shuffled gait
• Being unable to move
• Falling
• Fever, perspiration, dizziness, rapid breathing, erratic heartbeat, and extreme muscle stiffness
• Muscular ache or weakness
• Blank look on the face
• Breathing or swallowing challenges
• Throat constriction
• Tongue protruding from the mouth
• Rash
• Itching
• Hives
• Swelling of the lips, eyes, tongue, cheeks, or throat
• Urine with a cola or dark hue
• Swelling of the feet and legs
• Less urinations

Further negative effects of cariprazine are possible. If you experience any strange issues while taking this medicine, contact your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

Keep this medication tightly closed in the original container and out of the reach of children. Keep it away from excessive heat and moisture at room temperature (not in the bathroom).

Unused prescriptions must be disposed of carefully to prevent pets, kids, and other people from ingesting them. You should not, however, dispose of this medication in the toilet. Instead, utilising a medicine take-back programme is the easiest approach to get rid of your medication. To find out about take-back programmes in your area, speak with your pharmacist or the garbage/recycling department in your city. If you do not have access to a take-back programme, see the FDA’s Safe Disposal of Medications website at http://goo.gl/c4Rm4p for additional information.

Although many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Always lock safety caps and promptly stash medication up and away from young children where it is out of their sight and reach to prevent poisoning. http://www.upandaway.org

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Moreover, information can be found online at https://www.poisonhelp.org/help. Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

Overdose signs could include the following:

• Sedation
• Feeling sick or lightheaded when getting out of a seated or lying down position

Keep all of your appointments with your physician and the lab. To determine how your body is responding to cariprazine, your doctor may request specific lab tests.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.