Why is this medication prescribed?

Cardene SR (sustained-release formulation of nicardipine) is typically prescribed to manage high blood pressure (hypertension) in adults. Nicardipine belongs to a class of medications known as calcium channel blockers. It works by relaxing blood vessels, allowing blood to flow more easily, thus lowering blood pressure.

How should this medicine be used?

Cardene SR (nicardipine) is usually prescribed for the treatment of hypertension (high blood pressure). The medication comes in extended-release capsules, and it should be used exactly as prescribed by a healthcare professional. Here’s a general guideline on how Cardene SR should be used:

• Dosage: The dosage of Cardene SR varies depending on individual medical conditions and response to treatment. Your healthcare provider will determine the appropriate dosage for you based on factors such as your age, weight, overall health, and the severity of your hypertension.
• Administration: Cardene SR capsules are usually taken orally, with or without food. Swallow the capsules whole with a full glass of water. Do not crush, chew, or break the capsules, as this can alter the extended-release mechanism and may lead to an increased risk of side effects.
• Frequency: Cardene SR is typically taken once daily. Follow the dosing schedule provided by your healthcare provider. It’s essential to take the medication at the same time each day to maintain consistent levels of the drug in your bloodstream.
• Adherence: It’s crucial to adhere to the prescribed dosage and schedule. Do not skip doses or double up on doses to make up for missed ones unless instructed by your doctor.
• Monitoring: Your healthcare provider may periodically monitor your blood pressure and overall response to Cardene SR treatment. Attend all follow-up appointments as scheduled and report any concerns or side effects to your doctor promptly.
• Duration: Continue taking Cardene SR for as long as prescribed by your healthcare provider, even if you feel well. Stopping the medication abruptly could lead to a sudden increase in blood pressure.
• Interactions: Inform your healthcare provider about all medications, supplements, and herbal products you are currently taking, as they may interact with Cardene SR.
• Side Effects: Be aware of potential side effects of Cardene SR, such as dizziness, headache, flushing, swelling, or constipation. If you experience any severe or persistent side effects, contact your healthcare provider.

Always follow your healthcare provider’s instructions precisely when using Cardene SR or any medication. If you have any questions or concerns about how to use Cardene SR, consult your doctor or pharmacist for clarification.

Other uses for this medicine

While Cardene SR (nicardipine) is primarily prescribed for the treatment of hypertension (high blood pressure), it may also be used off-label or for other medical conditions as determined by a healthcare professional. Some potential off-label uses may include the management of certain types of angina (chest pain) or Raynaud’s phenomenon (a condition causing decreased blood flow to the fingers and toes).

What special precautions should I follow?

When taking Cardene SR, it’s essential to follow special precautions to ensure safe and effective use. Here are some key precautions to keep in mind:

• Allergies: Inform your healthcare provider if you have any allergies to nicardipine or any other medications.
• Medical History: Before starting Cardene SR, provide your healthcare provider with a comprehensive medical history, including any past or present medical conditions such as liver disease, heart disease, kidney disease, or any conditions affecting the blood vessels.
• Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the potential risks and benefits of using Cardene SR with your healthcare provider. Nicardipine may not be recommended during pregnancy or breastfeeding unless the benefits outweigh the risks.
• Interactions: Cardene SR may interact with other medications, including prescription drugs, over-the-counter medicines, herbal supplements, and vitamins. Inform your healthcare provider about all medications and supplements you are currently taking to avoid potential interactions.
• Driving and Operating Machinery: Cardene SR may cause dizziness or lightheadedness, especially when starting treatment or changing the dosage. Avoid driving, operating machinery, or engaging in activities requiring mental alertness until you know how this medication affects you.
• Alcohol: Limit or avoid alcohol consumption while taking Cardene SR, as it may worsen certain side effects such as dizziness or fainting.
• Grapefruit: Avoid consuming grapefruit or grapefruit juice while taking Cardene SR, as it may increase the levels of nicardipine in your bloodstream, potentially leading to an increased risk of side effects.
• Monitoring: Your healthcare provider may periodically monitor your blood pressure, heart rate, and overall response to Cardene SR treatment. Attend all follow-up appointments as scheduled and report any concerns or side effects to your doctor promptly.

Always adhere to your healthcare provider’s instructions and consult them if you have any questions or concerns about the use of Cardene SR or any medication.

What special dietary instructions should I follow?

Regarding dietary instructions, there are no specific dietary restrictions associated with Cardene SR. However, maintaining a healthy diet low in sodium and saturated fats can complement the treatment of hypertension.

What should I do if I forget a dose?

If you forget to take a dose of Cardene SR, take it as soon as you remember. However, if it’s almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double up on doses to make up for a missed one. If you’re unsure about what to do, consult your healthcare provider or pharmacist for guidance.

What side effects can this medication cause?

Cardene SR (nicardipine) may cause side effects in some individuals. Common side effects include:

• Dizziness: Feeling lightheaded or dizzy is a common side effect of Cardene SR, especially when standing up from a sitting or lying position.
• Headache: Some people may experience headaches while taking Cardene SR.
• Flushing: A temporary sensation of warmth or flushing of the skin may occur.
• Peripheral Edema: Swelling of the hands, ankles, or feet may occur due to fluid retention.
• Hypotension: Cardene SR may lower blood pressure, leading to symptoms such as weakness, fatigue, or fainting.
• Nausea: Some individuals may experience nausea or stomach discomfort.
• Constipation: Cardene SR may cause constipation in some people.
• Palpitations: A sensation of rapid or irregular heartbeat may occur.
• Rash: Skin rash or itching may occur in rare cases.
• Other: Other less common side effects may include nervousness, insomnia, muscle cramps, and visual disturbances.

It’s important to note that not everyone will experience these side effects, and some individuals may experience different or additional side effects. If you experience severe or persistent side effects while taking Cardene SR, or if you have any concerns about side effects, contact your healthcare provider for further evaluation and guidance. Additionally, if you experience any symptoms of a serious allergic reaction, such as rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, or difficulty breathing, seek immediate medical attention.

What should I know about storage and disposal of this medication?

Storage and disposal of Cardene SR:

• Storage: Store Cardene SR capsules at room temperature, away from moisture and heat. Keep the medication in its original container, tightly closed, and out of reach of children.
• Disposal: Dispose of unused or expired Cardene SR capsules properly according to local regulations or guidelines. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Consult your pharmacist or local waste disposal company for proper disposal instructions.

In case of emergency/overdose

• Seek Medical Assistance: If you suspect an overdose or experience symptoms such as severe dizziness, fainting, rapid or irregular heartbeat, or difficulty breathing, seek immediate medical attention or contact your local poison control center.
• Symptomatic Treatment: Emergency medical personnel will provide supportive care and treatment based on the symptoms present. Treatment may include close monitoring of vital signs, administration of intravenous fluids, and other supportive measures as needed.

What other information should I know?

• Regular Monitoring: Your healthcare provider may periodically monitor your blood pressure, heart rate, and overall response to Cardene SR treatment. Attend all follow-up appointments as scheduled.
• Avoid Alcohol: Limit alcohol consumption while taking Cardene SR, as it may worsen certain side effects such as dizziness or lightheadedness.
• Avoid Grapefruit: Avoid consuming grapefruit or grapefruit juice while taking Cardene SR, as it may affect drug levels in the bloodstream.
• Inform Healthcare Providers: Inform all healthcare providers involved in your care about your use of Cardene SR, including dentists and pharmacists, to avoid potential interactions with other medications.
• Keep a List of Medications: Maintain an updated list of all medications, supplements, and herbal products you are taking and share it with your healthcare provider to prevent potential drug interactions.
• Follow Instructions: Follow your healthcare provider’s instructions precisely regarding dosage, administration, and any special precautions or dietary instructions.
• Do Not Share: Do not share Cardene SR with others, even if they have similar symptoms or medical conditions, as it may not be suitable or safe for them.

Always consult your healthcare provider or pharmacist if you have any questions or concerns about the use of Cardene SR or any medication.