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Capmatinib

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Why is this medication prescribed?

A specific kind of non-small cell lung cancer (NSCLC) that has spread to the body is treated with capmatinib. The drug capmatinib belongs to the group of drugs known as kinase inhibitors. It functions by preventing the action of a problematic protein that instructs cancer cells to proliferate. This aids in containing or halting the spread of cancer cells.

How should this medicine be used?

Capmatinib is available as an oral tablet. Most people take it twice a day, with or without food. Take capmatinib every day at around the same time(s). Ask your doctor or pharmacist to explain any instructions on your prescription label that you are unsure about following. Follow the capmatinib directions exactly. Never take it in larger or less amounts or more frequently than directed by your doctor.

Do not chew, break, or crush the tablets; instead, swallow them whole.

Do not take another dose of capmatinib if you vomit after taking it. Continue taking your medication as usual.

Your therapy may need to be stopped temporarily or permanently by your doctor, or your capmatinib dosage may need to be reduced while you are receiving it. The effectiveness of the drug and any negative side effects you encounter will determine this. While you receive capmatinib treatment, be sure to discuss your feelings with your doctor.

For a copy of the manufacturer’s information for the patient, ask your pharmacist or doctor.

Other uses for this medicine

Ask your doctor or pharmacist for more details if you think this drug may be recommended for other conditions.

What special precautions should I follow?

Before taking capmatinib,

  • If you have an allergy to capmatinib, any other medications, or any of the ingredients in capmatinib tablets, let your doctor and pharmacist know right away. Get a list of the components from your pharmacist.
  • Inform your doctor and pharmacist about any additional prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products you are now taking or intend to use. Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects.
  • Capmatinib may interact with the nonprescription or natural products listed below: John’s Wort. Before beginning capmatinib therapy, be careful to inform your physician and pharmacist that you are taking these medications. While taking capmatinib, avoid starting any of these medications without first consulting your doctor.
  • Inform your doctor if you have or have previously had lung illness or breathing issues unrelated to liver disease, pancreatitis (pancreatic edema), or lung cancer.
  • If you are pregnant or plan to become pregnant, inform your doctor right away. Pregnancy should not occur when taking capmatinib. Before beginning therapy, you must have a pregnancy test, and you must take birth control to avoid becoming pregnant while receiving treatment and for at least a week after your last dosage. Use birth control to prevent pregnancy if you’re a guy with a female partner who might get pregnant both during treatment and for at least a week following your last dosage. Your unborn child could be harmed by capmatinib. Call your doctor right away if you or your partner become pregnant while taking capmatinib.
  • If you are breastfeeding, let your doctor know. While using capmatinib and for at least a week following your last dose, breastfeeding should be avoided.
  • Plan to limit your time in the sun and to cover up with a hat, additional UV-protective clothes, sunglasses, and sunscreen.

What special dietary instructions should I follow?

Keep eating normally unless your doctor instructs you otherwise.

What should I do if I forget a dose?

Ignore the missed dose and carry on with my normal dosing routine. To make up for a missing dose, do not take a second one.

What side effects can this medication cause?

Side effects with capmatinib are possible. If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Vomiting
  • Nausea
  • Diarrhea
  • Constipation
  • Back, bone, or muscular pain
  • Reduced appetite
  • Fatigue and fragility
  • Dizziness
  • Edema in the lower legs, ankles, feet, or h
  • Rash

Some adverse effects may be severe. Call your doctor right away or seek emergency medical attention if you have any of these symptoms:

  • Breathing difficulties, cough, fever, or other infection-related symptoms
  • Chest ache
  • Right upper stomach pain, stomach swelling, unusual bruising or bleeding, dark urine, skin and eye yellowing, nausea, vomiting, and light-colored feces; reduced appetite
  • Persistent stomach pain that occasionally radiates to the back, along with nauseousness, vomiting, and weight loss

Other adverse effects of capmatinib could occur. If you have any strange side effects while taking this medicine, call your doctor right away.

You or your doctor can report a significant side effect to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting program by phone or online at http://www.fda.gov/Safety/MedWatch.

What should I know about storage and disposal of this medication?

Keep this medication out of the reach of children, tightly closed in the container it comes in. Keep it away from excessive heat and moisture at room temperature. Keep the desiccant in your bottle; it is a tiny cartridge that is included with the tablets to absorb moisture. All unused pills should be thrown away six weeks after the bottle is first opened.

Although many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Always lock safety caps and promptly stash medication up and away from young children where it is out of their sight and reach to prevent poisoning. http://www.upandaway.org

Unused prescriptions must be disposed of carefully to prevent pets, kids, and other people from ingesting them. You should not, however, dispose of this medication in the toilet. Instead, utilizing a medicine take-back program is the easiest approach to get rid of your medication. To find out about take-back programs in your area, speak with your pharmacist or the garbage/recycling department in your city. If you do not have access to a take-back program, see the FDA’s Safe Disposal of Medications website at http://goo.gl/c4Rm4p for additional information.

In case of emergency/overdose

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Moreover, information can be found online at https://www.poisonhelp.org/help. Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

What other information should I know?

Keep all of your appointments with your physician and the lab. To monitor your body’s reaction to capmatinib, your doctor will request specific lab tests.

No one else should take your medication. Any queries you may have regarding medication refills should be directed to your pharmacist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • Tabrecta®
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