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Candesartan

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WARNING

If you are pregnant or want to become pregnant, let your doctor know. If you are pregnant, avoid using candesartan. If you become pregnant while using candesartan, notify your doctor right away and stop taking the medication. When used in the final six months of pregnancy, candesartan may result in the fetus’s death or severe damage.

Why is this medication prescribed?

Candesartan is used to treat high blood pressure either alone or in combination with other drugs. Congestive heart failure is also treated with candesartan, either by itself or in conjunction with other drugs (a condition when your heart can not pump enough blood to the other parts of the body). A group of drugs known as angiotensin II receptor antagonists includes candesartan. It functions by preventing the tightening of blood arteries caused by several natural chemicals, allowing blood to flow more freely and the heart to pump more effectively.

High blood pressure is a common illness that, if left untreated, can harm the kidneys, brain, heart, blood vessels, and other organs. Heart disease, a heart attack, heart failure, a stroke, renal failure, eyesight loss, and other issues may result from damage to these organs. Making lifestyle modifications will help you control your blood pressure in addition to taking medication. These adjustments include quitting smoking, drinking alcohol in moderation, eating a diet low in fat and salt, keeping a healthy weight, and exercising for at least 30 minutes most days.

How should this medicine be used?

An oral pill is available for candesartan. With or without food, it is often taken once or twice day. Take candesartan at about the same time(s) every day to make it easier for you to remember to take it. Ask your doctor or pharmacist to explain any instructions on your prescription label that you are unsure about following. Follow the candesartan directions precisely. Never take it in larger or less amounts or more frequently than directed by your doctor.

A modest dose of candesartan will likely be prescribed by your doctor, who will then likely progressively raise it not more frequently than once every two weeks.

Although it doesn’t treat high blood pressure, candesartan manages it. Although your blood pressure may drop during the first two weeks of treatment, it could take up to six weeks before you get candesartan’s full benefits. Even if you feel good, keep taking candesartan. Without consulting your doctor, do not discontinue taking candesartan.

Other uses for this medicine

Treatment for diabetic nephropathy with candesartan is also occasionally employed (kidney disease in people with diabetes and high blood pressure). Discuss the dangers of using this drug for your illness with your doctor.

Ask your doctor or pharmacist for more details if you believe this drug may be recommended for another purpose.

What special precautions should I follow?

Before taking candesartan,

  • If you have an allergy to candesartan, any other drugs, or any of the ingredients in candesartan tablets, let your doctor and pharmacist know right away. Get a list of the components from your pharmacist.
  • If you are taking aliskiren and have diabetes (high blood sugar), let your doctor know (Tekturna, in Amturnide, Tekamlo, Tekturna HCT). If you have diabetes and are also on aliskiren, your doctor will likely advise against taking candesartan.
  • Inform your doctor and pharmacist about any additional prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products you are now taking or intend to use. Incorporate any of the following: Benazepril (Lotensin, in Lotrel), captopril (Capoten, in Capozide), enalapril (Vasotec), fosinopril, lisinopril (in Prinzide, in Zestoretic), moexipril (Univasc, in Uniretic), perindopril (Aceon), and quinapril are examples of ACE inhibitors (Accupril, in Accuretic, in Quinaretic), aspirin and other NSAIDs including ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn), ramipril (Altace), and trandolapril (Mavik, in Tarka); diuretics (often known as “water pills”); lithium (Lithobid); drugs for diabetes; other prescriptions for high blood pressure; and potassium supplements. The dosage of your drugs may need to be adjusted, and your health may need to be closely watched for any negative effects.
  • Inform your physician if you now have or have ever had liver, renal, or cardiac illness.
  • If you are breastfeeding, let your doctor know.
  • Inform the surgeon or dentist that you are taking candesartan if you are undergoing surgery, including dental surgery.
  • When you get up too rapidly from a resting position while taking candesartan, you should be aware that these side effects could occur. When you initially start taking candesartan, this is more typical. Get out of bed gradually, resting your feet on the floor for a few minutes before rising up, to help prevent this issue.
  • You should be aware that a reduction in blood pressure might result from diarrhoea, vomiting, dehydration, and excessive perspiration, which can make you feel faint and dizzy. If you have any of these issues or if any emerge while you are receiving treatment, let your doctor know.

What special dietary instructions should I follow?

Do not use salt substitutes containing potassium without talking to your doctor. If your doctor prescribes a low-salt or low-sodium diet, follow these directions carefully.

What should I do if I forget a dose?

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What side effects can this medication cause?

Candesartan may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • Headache
  • Back pain
  • Sore throat

Some side effects can be serious. If you experience any of these symptoms or those listed in the SPECIAL PRECAUTIONS section, call your doctor immediately:

  • Swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
  • Hoarseness
  • Difficulty breathing or swallowing
  • Decreased urination

Candesartan may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting program online or by phone (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA’s Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

Although many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Always lock safety caps and promptly stash medication up and away from young children where it is out of their sight and reach to prevent poisoning. http://www.upandaway.org

In case of emergency/overdose

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can’t be awakened, immediately call emergency services at 911.

Symptoms of overdose may include the following:

  • Dizziness
  • Fainting
  • Fast or slow heart beat

What other information should I know?

Keep all appointments with your doctor and the laboratory. Your blood pressure should be checked regularly to determine your response to candesartan.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Brand names

  • Atacand®
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