WARNING

GHB is also known as calcium, magnesium, potassium, and sodium oxybate. It is a drug that is frequently marketed illegally and taken excessively, particularly by young adults in public places like nightclubs. Inform your physician if you use or have ever used street drugs, excessively utilized prescription medications, or consume a lot of alcohol. It can be dangerous to take calcium, magnesium, potassium, and sodium oxybate for purposes other than those for which it was recommended. It is illegal to share or sell calcium, magnesium, potassium, and sodium oxybate, so please don’t do either. Keep sodium, potassium, magnesium, and calcium oxybate in a secure location, like a closed cabinet or box, to prevent accidental or intentional theft. To ensure you are aware of any lost liquid, keep note of the amount remaining in your bottle.

Prolonged usage of calcium, magnesium, potassium, and sodium oxybate may result in severe adverse effects, which include potentially fatal respiratory issues. During your therapy with calcium, magnesium, potassium, and sodium oxybate, taking certain medications may raise your chance of experiencing severe or fatal breathing issues, drowsiness, or fainting. Inform your physician if you use sleeping drugs. When using this drug, your doctor will usually advise against taking calcium, magnesium, potassium, and sodium oxybate. Inform your physician about any antidepressants you may be taking, as well as benzodiazepines like temazepam (Restoril), clonazepam (Klonopin), diazepam (Diastat, Valium), estazolam, flurazepam, lorazepam (Ativan), oxazepam, temazepam (Xanax), and triazolam (Halcion); medications for muscle relaxants, mental illness, nausea, or seizures, or opioid painkillers. Your doctor might need to closely monitor you and adjust the dosages of your drugs. If you take calcium, magnesium, potassium, and sodium oxybate, avoid drinking alcohol.

Retail pharmacies do not carry sodium, potassium, magnesium, calcium, or oxybate products. Only through the Xywav and Xyrem REMS Program, a restricted distribution program, is calcium, magnesium, potassium, and sodium oxybate accessible. The drug is being distributed as part of a unique initiative that also offers information on the medication. After you have read the instructions and spoken with a pharmacist, your medication will be mailed to you from a central pharmacy. If you have any concerns about how your prescription will be administered, speak with your doctor.

The manufacturer’s patient information sheet (Medication Guide), which you will receive from your doctor or pharmacist when you start therapy with calcium, magnesium, potassium, and sodium oxybate, as well as each time you refill your prescription. If you have any questions, make sure to approach your pharmacist or doctor after thoroughly reading the material. Keep all of your doctor’s appointments.

Discuss the dangers of taking potassium, sodium oxybate, magnesium, and calcium with your physician.

Why is this medication prescribed?

In adults and children aged 7 and older with narcolepsy, calcium, magnesium, potassium, and sodium oxybate are used to treat excessive daytime sleepiness and cataplexy (sudden, uncontrollably sudden episodes of muscle weakness) (a sleep disorder that may cause sudden, uncontrollable urge to sleep during daily activities, and cataplexy). Adults with idiopathic hypersomnia (IH; a sleep disorder that may produce extreme daytime sleepiness and an insatiable drive to sleep throughout everyday activities despite adequate or prolonged nightly sleep) can also be treated with calcium, magnesium, potassium, and sodium oxybate. Sodium oxybate, potassium, magnesium, calcium, and sodium belong to a class of drugs known as central nervous system depressants. By decreasing brain activity, calcium, magnesium, potassium, and sodium oxybate help cure narcolepsy, cataplexy, and idiopathic hypersomnia.

How should this medicine be used?

The oxybate minerals calcium, magnesium, potassium, and sodium are available as a liquid that can be diluted with water and consumed orally. When calcium, magnesium, potassium, and sodium oxybate are used to treat cataplexy and excessive daytime sleepiness in cataplexy patients, they are typically taken twice a night because the effects of one dose will not last the entire night and the effects wear off quickly. When treating idiopathic hypersomnia, calcium, magnesium, potassium, and sodium oxybate are typically administered once or twice a night. A second dose is taken between two and three quarters of an hour following the first dose, which is taken at bedtime. The initial dose of calcium, magnesium, potassium, and sodium oxybate needs to be given at least two hours after meals because they must be taken on an empty stomach. Pay close attention to the instructions on the label of your prescription and ask your pharmacist or doctor to explain anything you do not understand.

Calcium, magnesium, potassium, and sodium oxybate dosages should not be taken before you and your child are in bed and prepared for sleep for the night. Within five to fifteen minutes of consumption, calcium, magnesium, potassium, and sodium oxybate start to act. Put your second dose of calcium, magnesium, potassium, and sodium oxybate in a secure location close to your bed (or in a secure location to give it to your kid) before going to bed if your doctor has instructed you to do so. Make sure you wake up in time to take the second dose by setting an alarm clock. Take your second dose, turn off the alarm, and return to sleep if you or your child wakes up before the alarm goes off and it has been at least two and a half hours since you took your first dose.

Probably once a week at most, your doctor will start you on a modest amount of potassium, sodium oxybate, magnesium, calcium, and magnesium and gradually increase it.

Potassium, sodium oxybate, magnesium, calcium, and potassium may establish habits. Never take more of it or take it more frequently than your doctor has instructed. Overdosing on calcium, magnesium, potassium, and sodium oxybate can result in potentially fatal symptoms such as seizures, shallow or halted breathing, unconsciousness, and coma. Additionally, you might feel the need to take ever-higher dosages of calcium, magnesium, potassium, and sodium oxybate, develop a need for these nutrients, or decide to keep taking them despite experiencing unpleasant side effects. You may experience withdrawal symptoms, such as trouble falling or staying asleep, restlessness, anxiety, abnormal thinking, loss of contact with reality, sleepiness, upset stomach, shaking of a part of your body that you cannot control, sweating, muscle cramps, and fast heartbeat, if you have taken calcium, magnesium, potassium, and sodium oxybate in amounts greater than those prescribed by your doctor and you suddenly stop taking it.

Sodium oxybate, potassium, magnesium, calcium, and magnesium may assist manage your symptoms but cannot treat your illness. Even if you feel better, keep taking sodium oxybate, potassium, magnesium, and calcium supplements. Consult your doctor before ceasing to use potassium, sodium oxybate, magnesium, calcium, or magnesium supplements. It’s likely that your doctor will want to progressively reduce your dosage. You may have more cataplexy episodes, feel anxious, and have trouble falling or keeping asleep if you abruptly stop taking calcium, magnesium, potassium, and sodium oxybate.

Use these procedures to prepare dosages of potassium, sodium oxybate, magnesium, and calcium:

• Take out the measuring tool and the drug bottle from the carton your medication arrived in.
• Take the measuring gadget out of its packaging.
• Pressing down on the cap and simultaneously rotating it counterclockwise (to the left) will open the bottle.
• On a table, place the open bottle upright.
• With one hand, hold the bottle upright. Position the measuring device’s tip in the middle of the bottle’s top opening using your free hand. Firmly press the tip into the aperture.
• Using one hand, hold the measurement tool and the bottle. Pull the plunger back with your other hand until the marking corresponds to the dosage that your doctor has prescribed. To enable the medication to enter the measuring equipment, make sure the bottle is upright.
• Take out the measurement tool from the bottle’s top. Insert the measuring device’s tip into one of the dose cups that come with the prescription.
• To transfer the drug into the dosage cup, depress the plunger.
• Fill the dosing cup with 2 ounces (60 milliliters, 1/4 cup, or around 4 teaspoons) of tap water. Avoid combining the prescription with other liquids, such as fruit juice or soft drinks.
• Put the dosage cup’s cap on. Till the cap clicks and latches into place, turn it clockwise, or to the right.
• Repeat steps 5 through 10 to produce a second dose in a second dosing cup with sodium oxybate, potassium, magnesium, and calcium.
• Use water to rinse the measurement gadget.
• Put the measurement equipment and bottle of calcium, magnesium, potassium, and sodium oxybate back in a secure location away from kids and animals after replacing the cap. The prepared medication dosing cup(s) should be placed in a secure location next to your bed or somewhere safe that is out of your child’s and pets’ reach.
• When it’s time to take the first dose of sodium oxybate, potassium, magnesium, and calcium oxybate, turn the cap counterclockwise (to the left) by applying pressure. Sitting on your bed, drink the entire contents of the bottle. Replace the cup’s cap, spin it clockwise (to the right) to secure it, and then immediately lie down.
• In the event that you need to take a second dose, repeat step 14 when you wake up between two and four hours later.

Other uses for this medicine

Ask your doctor or pharmacist for more information if you think this medicine could be recommended for something else.

What special precautions should I follow?

When using Calcium, Magnesium, Potassium supplements or Sodium Oxybate, it’s important to follow these precautions:

• Dosage: Take these medications exactly as prescribed by your healthcare provider. Dosages vary depending on the specific condition being treated and individual needs.
• Monitoring: Regular monitoring of blood levels (e.g., calcium, magnesium, potassium) may be necessary to ensure that levels are within the therapeutic range and to prevent toxicity.
• Interaction with Other Medications: Inform your healthcare provider about all medications you are taking, including over-the-counter drugs and supplements, as interactions can occur.
• Side Effects: Be aware of potential side effects such as gastrointestinal upset (e.g., constipation with calcium), allergic reactions, and specific side effects related to each medication (e.g., CNS depression with Sodium Oxybate).
• Medical Conditions: Certain medical conditions may require adjustments in dosage or careful monitoring when using these supplements or medications. For instance, patients with kidney disease may need adjusted dosages of potassium and calcium supplements.
• Pregnancy and Lactation: Consult with your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding, as special considerations may apply for the use of these medications.

Always seek guidance from a healthcare professional regarding the appropriate use, dosage, and precautions specific to your medical condition and individual health needs.

What special dietary instructions should I follow?

Maintain your regular diet unless advised otherwise by your physician.

What should I do if I forget a dose?

If you forget to take your second dose of potassium, sodium oxybate, magnesium, calcium, or magnesium, just omit the missing dose and take your regular amount the following night. Never take two doses to make up for something you forgot to take. Between dosages of calcium, magnesium, potassium, and sodium oxybate, always give yourself at least 2 1/2 hours.

What side effects can this medication cause?

Here are the potential side effects associated with Calcium, Magnesium, Potassium supplements, and Sodium Oxybate:

• Bedwetting
• Headache
• Dizziness
• Shaking of a part of your body that you cannot control
• Feelings of numbness, tingling, pricking, burning, or creeping on the skin
• Difficulty moving when sleeping or upon waking
• Nausea
• Vomiting
• Diarrhea
• Dry mouth
• Irritability
• Weakness
• Muscle spasms
• Sweating

Certain adverse effects may be dangerous. Although not common, if you encounter any of the following symptoms, get emergency care or contact your doctor right away:

• Sleepwalking
• Abnormal dreams
• Agitation
• Aggression
• Anxiety
• Depression
• Confusion or memory problems
• Changes in weight or appetite
• Feelings of guilt
• Thoughts of harming or killing yourself
• Feeling that others want to harm you
• Hallucinations (seeing things or hearing voices that do not exist)
• Loss of contact with reality
• Breathing problems, snoring, or sleep apnea
• Excessive drowsiness during the day

It’s important to note that these side effects can vary in severity and occurrence depending on the individual and the dosage of the medication or supplement. Always follow your healthcare provider’s recommendations regarding dosage and be vigilant for any unusual symptoms while taking these medications or supplements. If you experience severe or persistent side effects, contact your healthcare provider promptly.

What should I know about storage and disposal of this medication?

Storage and Disposal: Store this prescription tightly closed in the original container, out of the reach of kids and animals. Keep it out of the bathroom and at room temperature, away from sources of heat and moisture. If the medication was prepared more than 24 hours ago, flush any leftovers down the sink. Using a marker, cross out the bottle’s label, then throw the empty bottle in the garbage. If you have any doubts regarding how to properly dispose of your prescription that is no longer needed or expired, ask your doctor or give the central pharmacy a call.

Since many prescription containers including weekly pill minders and those for eye drops, creams, patches, and inhalers are not child-resistant and are readily opened by small children, it is crucial to keep all medication out of children’s sight and access. Always lock safety caps on medications to prevent poisoning in small children, and store them right away in a secure spot that is out of their reach and sight.

It is important to dispose of unnecessary prescriptions in a specific manner so that children, dogs, and other people cannot ingest them. But this drug is not something you should flush down the toilet. The best way to get rid of your medication is to use a service called medicine take-back. To find out more about take-back initiatives in your area, speak with your pharmacist or get in touch with the recycling and trash department.

In case of emergency/overdose

In Case of Emergency or Overdose:

• Call Emergency Services: If you suspect an overdose or experience severe symptoms, such as difficulty breathing, loss of consciousness, irregular heartbeat, or severe gastrointestinal distress, call emergency services immediately (e.g., 911 in the United States).
• Poison Control: Contact your local poison control center or emergency department for guidance on what to do next. Have the medication container or label with you if possible to provide accurate information.

What other information should I know?

• Follow Prescribed Dosage: Always take these medications as prescribed by your healthcare provider. Do not exceed the recommended dosage unless instructed to do so.
• Regular Monitoring: Attend all follow-up appointments as scheduled to monitor your response to treatment and check for any potential side effects or complications.
• Medication Interactions: Inform your healthcare provider about all medications (prescription, over-the-counter, herbal supplements) you are taking, as they can interact with calcium, magnesium, potassium supplements, and sodium oxybate.
• Avoid Alcohol: Especially with sodium oxybate (Xyrem), avoid alcohol and other central nervous system depressants, as they can increase the risk of severe side effects.
• Driving and Operating Machinery: Sodium oxybate can cause dizziness and drowsiness. Avoid driving or operating machinery until you know how this medication affects you.

By understanding these aspects of storage, disposal, emergencies/overdose, and other relevant information, you can safely manage your medication regimen and seek appropriate help if needed. Always consult your healthcare provider for personalized advice regarding your specific health needs.