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Brethine (Generic Terbutaline Injection)

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WARNING

Although the Food and Drug Administration has not given its approval for this application, terbutaline injection is occasionally used to stop or prevent premature labour in pregnant women. Terbutaline injection shouldn’t be used to treat premature labour for more than 48 to 72 hours unless a woman is already receiving care in a hospital. When terbutaline was utilised for this purpose, it has resulted in fatal side effects in pregnant women. Infants whose moms used terbutaline to induce or stop labour have also experienced severe negative effects.

Why is this medication prescribed?

Terbutaline injection is used to treat asthma, chronic bronchitis, and emphysema-related wheezing, shortness of breath, coughing, and chest tightness. Beta agonists are a group of drugs that includes terbutaline. It facilitates breathing by calming down and widening the airways.

How should this medicine be used?

Terbutaline injection is available as a solution (liquid) to administer intravenously. When necessary, it is typically administered by a doctor or nurse in a medical setting to treat the signs and symptoms of emphysema, chronic bronchitis, or asthma. A second dose may be used if the symptoms do not subside within 15 to 30 minutes of the initial dose. A alternative form of treatment needs to be used if the symptoms do not disappear within 15 to 30 minutes of the second dose.

Other uses for this medicine

Terbutaline injection may also be administered to pregnant patients who are experiencing premature labour for a brief period of time (less than 48 to 72 hours). The dangers of using this drug for your illness should be discussed with your doctor.

Ask your doctor or pharmacist for more details if you believe this drug should be used for something else.

What special precautions should I follow?

Before receiving terbutaline injection,

  • If you have an allergy to terbutaline, any other drugs, or any of the components in terbutaline injection, let your doctor and pharmacist know right away. Request a list of the components from your pharmacist.
  • Inform your doctor and pharmacist about all prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products that you are now taking or intend to use. Incorporate any of the following: beta blockers such labetalol, atenolol (Tenormin), and carteolol (Normodyne, Trandate), metoprolol (Lopressor), nadolol (Corgard), propranolol (Inderal), sotalol (Betapace), and timolol (Blocadren); some diuretics (‘water pills’); additional asthma treatments; medications for colds; medications for appetite control; and drugs for attention-deficit hyperactivity disorder. Also let your physician know if you are currently taking any of the following drugs or if you have stopped taking them within the previous two weeks: tricyclic antidepressants like amitriptyline, amoxapine, clomipramine (Anafranil), desipramine (Norpramin), doxepin, imipramine (Tofranil), maprotiline, nortriptyline (Pamelor), protriptyline (Vivactil), and (Parnate). Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects.
  • Inform your doctor if you currently have or have ever had seizures, diabetes, high blood pressure, an overactive thyroid gland, an irregular heartbeat, or heart problems.
  • Inform your doctor if you are expecting, intend to get pregnant, or are nursing a baby. Call your doctor if you become pregnant while receiving terbutaline injections.

What special dietary instructions should I follow?

Keep eating normally unless your doctor instructs you otherwise.

What side effects can this medication cause?

Side effects from terbutaline injection are possible. If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Body part shaking that is uncontrollable
  • Nervousness
  • Dizziness
  • Drowsiness
  • Weakness
  • Headache
  • Nausea
  • Vomiting
  • Sweating
  • Flushing (sense of warmth)
  • Pain from an injection

Some adverse effects can be very harmful. Call your doctor right away if any of these symptoms occur to you:

  • Increased breathing difficulty
  • Throat tightening sensation
  • Hammering, rapid, or erratic heartbeat
  • Chest pain
  • Seizures

Other negative consequences from terbutaline injection are possible. If you have any strange side effects while taking this medicine, call your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

In case of emergency/overdose

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Additionally, information can be found online at https://www.poisonhelp.org/help. Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

Overdose symptoms could include:

  • Chest pain
  • Hammering, rapid, or erratic heartbeat
  • Fainting or vertigo
  • Nervousness
  • Headache
  • Body part shaking that is uncontrollable
  • Excessive fatigue
  • Having trouble falling or staying asleep
  • Weakness
  • Mouth ache
  • Seizures

What other information should I know?

Keep all of your doctor’s appointments.

If you have any inquiries regarding terbutaline injection, ask your pharmacist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • Brethine®
  • Bricanyl®
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