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Brenzavvy (Generic Bexagliflozin)

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Why is this medication prescribed?

Brenzavvy, also known as generic Bexagliflozin, is prescribed primarily for the treatment of type 2 diabetes mellitus. It belongs to a class of medications called SGLT2 inhibitors (sodium-glucose co-transporter 2 inhibitors). These drugs work by helping the kidneys remove glucose from the bloodstream through the urine, thereby lowering blood sugar levels.

In addition to lowering blood sugar levels, Brenzavvy has been shown to have other potential benefits such as weight loss and reduction in blood pressure. It is typically prescribed as part of a comprehensive treatment plan that includes diet, exercise, and possibly other diabetes medications.

How should this medicine be used?

As for how it should be used, Brenzavvy tablets are usually taken once daily, with or without food. The dosage prescribed by your healthcare provider will depend on various factors such as your medical condition, response to treatment, and other medications you may be taking.

It’s essential to follow your doctor’s instructions carefully when taking Brenzavvy. Do not take more or less of it than prescribed, and do not stop taking it without consulting your healthcare provider, even if you feel well. Consistent use is crucial for managing diabetes effectively.

If you miss a dose of Brenzavvy, take it as soon as you remember. However, if it’s almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double dose to make up for a missed one.

It’s also important to monitor your blood sugar levels regularly while taking Brenzavvy, as directed by your doctor. Be aware of any signs of low blood sugar (hypoglycemia) or high blood sugar (hyperglycemia) and report any concerns to your healthcare provider promptly.

Always store Brenzavvy tablets at room temperature, away from moisture and heat, and keep them out of the reach of children. If you have any questions or concerns about how to use Brenzavvy, don’t hesitate to discuss them with your doctor or pharmacist.

Other uses for this medicine

While Brenzavvy (Bexagliflozin) is primarily prescribed for the management of type 2 diabetes, there might be other potential uses that are being explored or off-label uses that your healthcare provider may consider based on your individual circumstances. However, it’s important to note that using medications for off-label purposes should always be done under the guidance and supervision of a healthcare professional.

What special precautions should I follow?

As for special precautions to follow when taking Brenzavvy:

  • Kidney Function: Since Brenzavvy works by affecting kidney function to lower blood sugar levels, it’s essential to monitor kidney function regularly while taking this medication. Your healthcare provider will likely perform kidney function tests before starting Brenzavvy and periodically thereafter.
  • Dehydration: Brenzavvy can increase the risk of dehydration, particularly in older adults or individuals with existing kidney problems. It’s important to drink plenty of fluids while taking this medication and to be aware of signs of dehydration such as dizziness, lightheadedness, or decreased urination.
  • Genital Infections: Some individuals may experience genital yeast infections or urinary tract infections while taking Brenzavvy. Be mindful of any symptoms such as itching, burning, or unusual discharge and promptly report them to your healthcare provider if they occur.
  • Low Blood Sugar (Hypoglycemia): While Brenzavvy primarily works by removing excess glucose from the bloodstream, it can occasionally lead to low blood sugar levels, especially when combined with other diabetes medications such as insulin or sulfonylureas. Be aware of symptoms of hypoglycemia such as sweating, shaking, fast heartbeat, confusion, and hunger, and have a plan in place for managing low blood sugar episodes.
  • Other Medications and Medical Conditions: Inform your healthcare provider about all medications you are taking, including over-the-counter drugs and supplements, as well as any medical conditions you have, particularly if you have a history of kidney problems, urinary tract infections, or dehydration.

Always follow your healthcare provider’s instructions and recommendations regarding the use of Brenzavvy, including dosage, timing, and any additional precautions specific to your situation. If you have any questions or concerns about Brenzavvy or its potential uses, don’t hesitate to discuss them with your healthcare provider.

What special dietary instructions should I follow?

  • Healthy Eating: Follow a healthy diet as recommended by your healthcare provider or dietitian. This typically includes plenty of fruits, vegetables, whole grains, lean proteins, and healthy fats.
  • Carbohydrate Intake: Monitor your carbohydrate intake as part of your overall diabetes management plan. Brenzavvy helps lower blood sugar levels by removing glucose from the bloodstream, but controlling carbohydrate intake can also help stabilize blood sugar levels.

What should I do if I forget a dose?

  • Take it as Soon as Possible: If you forget a dose, take it as soon as you remember. However, if it’s almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule.
  • Do Not Double Dose: Do not take a double dose to make up for a missed one, as this can increase the risk of side effects.
  • Follow Up with Healthcare Provider: If you have questions or concerns about missed doses, contact your healthcare provider for guidance.

What side effects can this medication cause?

Brenzavvy (Bexagliflozin) can cause various side effects, although not everyone experiences them. Common side effects may include:

  • Genital Infections: This can include yeast infections in women and men, as well as urinary tract infections.
  • Dehydration: Since Brenzavvy works by increasing urine output to remove glucose from the body, it can lead to dehydration, especially if fluid intake is not sufficient.
  • Low Blood Sugar (Hypoglycemia): While less common than with some other diabetes medications, Brenzavvy can still occasionally cause low blood sugar levels, especially when used in combination with insulin or other blood sugar-lowering drugs.
  • Increased Urination: Due to its mechanism of action, Brenzavvy may cause an increase in urination.
  • Dizziness or Lightheadedness: Some individuals may experience dizziness or lightheadedness, particularly when standing up quickly, due to changes in blood pressure or dehydration.
  • Nausea: Nausea can occur as a side effect of Brenzavvy in some individuals.
  • Increased Cholesterol Levels: Brenzavvy may lead to increases in cholesterol levels, particularly low-density lipoprotein (LDL) cholesterol.
  • Bone Fractures: There may be an increased risk of bone fractures, particularly in the hands and feet, associated with long-term use of Brenzavvy.
  • Ketoacidosis: Although rare, Brenzavvy can increase the risk of a serious condition called diabetic ketoacidosis, particularly in individuals with type 1 diabetes or those with severely elevated blood sugar levels.

It’s important to note that this is not an exhaustive list of side effects, and other side effects may occur. Additionally, some side effects may require medical attention, while others may resolve on their own as your body adjusts to the medication.

If you experience any side effects while taking Brenzavvy, it’s essential to notify your healthcare provider. They can help determine whether the side effect is serious and provide guidance on how to manage it.

What should I know about storage and disposal of this medication?

When it comes to the storage and disposal of Brenzavvy (Bexagliflozin), here are some important points to keep in mind:


  • Store Brenzavvy at room temperature, away from moisture and heat.
  • Keep the medication in its original container with the lid tightly closed.
  • Store Brenzavvy out of reach of children and pets, as it can be harmful if ingested.


  • Dispose of any unused or expired Brenzavvy tablets properly according to local regulations or guidelines.
  • Do not flush Brenzavvy down the toilet or pour it down the drain unless instructed to do so by a healthcare professional or pharmacist.
  • Check with your pharmacist or local waste disposal facility for instructions on how to properly dispose of Brenzavvy.

In case of emergency/overdose

  • Contact emergency medical services (911 in the United States) or your local poison control center immediately.
  • If possible, provide them with information about the medication, including the name (Brenzavvy), dosage strength, and how much was taken.
  • Do not attempt to treat an overdose of Brenzavvy at home without medical guidance.

What other information should I know?

  • Keep all appointments with your healthcare provider for monitoring and follow-up visits while taking Brenzavvy.
  • Inform your healthcare provider about all medications you are currently taking, including over-the-counter drugs and supplements, to avoid potential interactions.
  • It’s essential to follow your healthcare provider’s instructions regarding diet, exercise, and other lifestyle changes while taking Brenzavvy to effectively manage your diabetes.
  • If you experience any new or worsening symptoms while taking Brenzavvy, such as persistent urinary tract infections, genital infections, or signs of dehydration, notify your healthcare provider promptly.
  • Carry identification or wear a medical alert bracelet indicating that you have diabetes and are taking Brenzavvy in case of emergencies.

By adhering to these guidelines and staying informed about Brenzavvy, you can safely and effectively manage your diabetes while minimizing the risk of complications.

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